Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
Le, Anne, Cooper, Charles R, Gouw, Arvin M, Dinavahi, Ramani, Maitra, Anirban, Deck, Lorraine M, Royer, Robert E, Vander Jagt, David L, Semenza, Gregg L, Dang, Chi V
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2010)
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Journal Article
A chemical analog of curcumin as an improved inhibitor of amyloid Abeta oligomerization
Orlando, Robert A, Gonzales, Amanda M, Royer, Robert E, Deck, Lorraine M, Vander Jagt, David L
Published in PloS one (19.03.2012)
Published in PloS one (19.03.2012)
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Journal Article
Activation of anti-oxidant Nrf2 signaling by substituted trans stilbenes
Deck, Lorraine M., Whalen, Lisa J., Hunsaker, Lucy A., Royer, Robert E., Vander Jagt, David L.
Published in Bioorganic & medicinal chemistry (15.02.2017)
Published in Bioorganic & medicinal chemistry (15.02.2017)
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Journal Article
Comparative Structural Analysis and Kinetic Properties of Lactate Dehydrogenases from the Four Species of Human Malarial Parasites
Brown, W. Michael, Yowell, Charles A, Hoard, Anna, Vander Jagt, Thomas A, Hunsaker, Lucy A, Deck, Lorraine M, Royer, Robert E, Piper, Robert C, Dame, John B, Makler, Michael T, Vander Jagt, David L
Published in Biochemistry (Easton) (25.05.2004)
Published in Biochemistry (Easton) (25.05.2004)
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Journal Article
Inhibition of Nuclear Factor κB Activation and Cyclooxygenase-2 Expression by Aqueous Extracts of Hispanic Medicinal Herbs
Orlando, Robert A, Gonzales, Amanda M, Hunsaker, Lucy A, Franco, Carolina R, Royer, Robert E, Vander Jagt, David L, Vander Jagt, Dorothy J
Published in Journal of medicinal food (01.08.2010)
Published in Journal of medicinal food (01.08.2010)
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Journal Article
Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum
Gomez, Manuel S, Piper, Robert C, Hunsaker, Lucy A, Royer, Robert E, Deck, Lorraine M, Makler, Michael T, Vander Jagt, David L
Published in Molecular and biochemical parasitology (01.12.1997)
Published in Molecular and biochemical parasitology (01.12.1997)
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Journal Article
Activation of NFκB is inhibited by curcumin and related enones
Weber, Waylon M., Hunsaker, Lucy A., Roybal, C. Nathaniel, Bobrovnikova-Marjon, Ekaterina V., Abcouwer, Steve F., Royer, Robert E., Deck, Lorraine M., Vander Jagt, David L.
Published in Bioorganic & medicinal chemistry (01.04.2006)
Published in Bioorganic & medicinal chemistry (01.04.2006)
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Journal Article
Synthesis of hemigossypol and its derivatives
Wei, Jun, Jagt, David L. Vander, Royer, Robert E., Deck, Lorraine M.
Published in Tetrahedron letters (03.11.2010)
Published in Tetrahedron letters (03.11.2010)
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Journal Article
Synthesis of benzyl substituted naphthalenes from benzylidene tetralones
Deck, Lorraine M., Mgani, Quintino, Martinez, Andrea, Martinic, Alice, Whalen, Lisa J., Vander Jagt, David L., Royer, Robert E.
Published in Tetrahedron letters (25.01.2012)
Published in Tetrahedron letters (25.01.2012)
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Journal Article
Selective active site inhibitors of human lactate dehydrogenases A4, B4, and C4
YUE YU, DECK, Jason A, HUNSAKER, Lucy A, DECK, Lorraine M, ROYER, Robert E, GOLDBERG, Erwin, VANDER JAGT, David L
Published in Biochemical pharmacology (01.07.2001)
Published in Biochemical pharmacology (01.07.2001)
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Journal Article
Metabolism of the 2-oxoaldehyde methylglyoxal by aldose reductase and by glyoxalase-I: roles for glutathione in both enzymes and implications for diabetic complications
Vander Jagt, David L., Hassebrook, Robyn K., Hunsaker, Lucy A., Brown, William M., Royer, Robert E.
Published in Chemico-biological interactions (30.01.2001)
Published in Chemico-biological interactions (30.01.2001)
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Journal Article
Selective Inhibitors of Human Lactate Dehydrogenases and Lactate Dehydrogenase from the Malarial Parasite Plasmodium falciparum
DECK, Lorraine M., ROYER, Robert E., CHAMBLEE, Brian B., HERNANDEZ, Valerie M., MALONE, Richard R., TORRES, Jose E., HUNSAKER, Lucy A., PIPER, Robert C., MAKLER, Michael T., VANDER JAGT, David L.
Published in Journal of medicinal chemistry (24.09.1998)
Published in Journal of medicinal chemistry (24.09.1998)
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Journal Article
Substrate specificity of human aldose reductase: identification of 4-hydroxynonenal as an endogenous substrate
bander Jagt, David L., Kolb, Natasha S., bander Jagt, Timothy J., Chino, Joachim, Martinez, Francella J., Hunsaker, Lucy A., Royer, Robert E.
Published in Biochimica et biophysica acta (12.06.1995)
Published in Biochimica et biophysica acta (12.06.1995)
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Journal Article
The kinetic properties and sensitivities to inhibitors of lactate dehydrogenases (LDH1 and LDH2) from Toxoplasma gondii: comparisons with pLDH from Plasmodium falciparum
Dando, Caroline, Schroeder, Eric R, Hunsaker, Lucy A, Deck, Lorraine M, Royer, Robert E, Zhou, Xiulan, Parmley, Stephen F, Vander Jagt, David L
Published in Molecular and biochemical parasitology (01.11.2001)
Published in Molecular and biochemical parasitology (01.11.2001)
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Journal Article
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes
Vander Jagt, David L., Hunsaker, Lucy A., Vander Jagt, Timothy J., Gomez, Manuel S., Gonzales, Donna M., Deck, Lorraine M., Royer, Robert E.
Published in Biochemical pharmacology (25.04.1997)
Published in Biochemical pharmacology (25.04.1997)
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Journal Article
17-β-Hydroxysteroid dehydrogenase type 1: computational design of active site inhibitors targeted to the Rossmann fold
Brown, William M, Metzger, Louis E, Barlow, Jeremy P, Hunsaker, Lucy A, Deck, Lorraine M, Royer, Robert E, Vander Jagt, David L
Published in Chemico-biological interactions (01.02.2003)
Published in Chemico-biological interactions (01.02.2003)
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Journal Article
Synthesis of Naphthoic Acids as Potential Anticancer Agents
Deck, Lorraine M., Greenberg, Jacob A., Whalen, Lisa J., Vander Jagt, David L., Royer, Robert E.
Published in Synlett (01.01.2019)
Published in Synlett (01.01.2019)
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