Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania
Bhattacharya, Arijit, Leprohon, Philippe, Bigot, Sophia, Padmanabhan, Prasad Kottayil, Mukherjee, Angana, Roy, Gaétan, Gingras, Hélène, Mestdagh, Anais, Papadopoulou, Barbara, Ouellette, Marc
Published in Nature communications (09.12.2019)
Published in Nature communications (09.12.2019)
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Journal Article
Genome-wide stochastic adaptive DNA amplification at direct and inverted DNA repeats in the parasite Leishmania
Ubeda, Jean-Michel, Raymond, Frédéric, Mukherjee, Angana, Plourde, Marie, Gingras, Hélène, Roy, Gaétan, Lapointe, Andréanne, Leprohon, Philippe, Papadopoulou, Barbara, Corbeil, Jacques, Ouellette, Marc
Published in PLoS biology (01.05.2014)
Published in PLoS biology (01.05.2014)
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Journal Article
Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species
Raymond, Frédéric, Boisvert, Sébastien, Roy, Gaétan, Ritt, Jean-François, Légaré, Danielle, Isnard, Amandine, Stanke, Mario, Olivier, Martin, Tremblay, Michel J., Papadopoulou, Barbara, Ouellette, Marc, Corbeil, Jacques
Published in Nucleic acids research (01.02.2012)
Published in Nucleic acids research (01.02.2012)
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Journal Article
The γ‐glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants
Mukherjee, Angana, Roy, Gaétan, Guimond, Chantal, Ouellette, Marc
Published in Molecular microbiology (01.11.2009)
Published in Molecular microbiology (01.11.2009)
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Journal Article
High-throughput Cos-Seq screen with intracellular Leishmania infantum for the discovery of novel drug-resistance mechanisms
Fernandez-Prada, Christopher, Sharma, Mansi, Plourde, Marie, Bresson, Eva, Roy, Gaétan, Leprohon, Philippe, Ouellette, Marc
Published in International journal for parasitology -- drugs and drug resistance (01.08.2018)
Published in International journal for parasitology -- drugs and drug resistance (01.08.2018)
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Journal Article
Decreased glutamate transport in acivicin resistant Leishmania tarentolae
Roy, Gaétan, Bhattacharya, Arijit, Leprohon, Philippe, Ouellette, Marc
Published in PLoS neglected tropical diseases (01.12.2021)
Published in PLoS neglected tropical diseases (01.12.2021)
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Journal Article
Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms
Fernandez-Prada, Christopher, Vincent, Isabel M, Brotherton, Marie-Christine, Roberts, Mathew, Roy, Gaétan, Rivas, Luis, Leprohon, Philippe, Smith, Terry K, Ouellette, Marc
Published in PLoS neglected tropical diseases (02.12.2016)
Published in PLoS neglected tropical diseases (02.12.2016)
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Journal Article
Role of ABC transporter MRPA, γ-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani
Mukherjee, Angana, Padmanabhan, Prasad K., Singh, Sushma, Roy, Gaétan, Girard, Isabelle, Chatterjee, Mitali, Ouellette, Marc, Madhubala, Rentala
Published in Journal of antimicrobial chemotherapy (01.02.2007)
Published in Journal of antimicrobial chemotherapy (01.02.2007)
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Journal Article
Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes
EL FADILI, Karima, MESSIER, Nadine, LEPROHON, Philippe, ROY, Gaétan, GUIMOND, Chantal, TRUDEL, Nathalie, SARAVIA, Nancy G, PAPADOPOULOU, Barbara, LEGARE, Danielle, OUELLETTE, Marc
Published in Antimicrobial Agents and Chemotherapy (01.05.2005)
Published in Antimicrobial Agents and Chemotherapy (01.05.2005)
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Journal Article
Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum
Genois, Marie-Michelle, Mukherjee, Angana, Ubeda, Jean-Michel, Buisson, Rémi, Paquet, Eric, Roy, Gaétan, Plourde, Marie, Coulombe, Yan, Ouellette, Marc, Masson, Jean-Yves
Published in Nucleic acids research (01.08.2012)
Published in Nucleic acids research (01.08.2012)
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Journal Article
Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice
Santi, Ana Maria Murta, Lanza, Juliane Sousa, Tunes, Luiza Guimarães, Fiuza, Jacqueline Araújo, Roy, Gaétan, Orfanó, Alessandra da Silva, de Carvalho, Andréa Teixeira, Frézard, Frédéric, Barros, André Luís Branco de, Murta, Silvane Maria Fonseca, do Monte-Neto, Rubens Lima
Published in Scientific reports (02.08.2018)
Published in Scientific reports (02.08.2018)
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Journal Article
Modulation of Gene Expression in Human Macrophages Treated with the Anti-Leishmania Pentavalent Antimonial Drug Sodium Stibogluconate
EL FADILI, Karima, IMBEAULT, Michaël, MESSIER, Nadine, ROY, Gaétan, GOURBAL, Benjamin, BERGERON, Marc, TREMBLAY, Michel J, LEGARE, Danielle, OUELLETTE, Marc
Published in Antimicrobial Agents and Chemotherapy (01.02.2008)
Published in Antimicrobial Agents and Chemotherapy (01.02.2008)
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Journal Article
Antimony Uptake Systems in the Protozoan Parasite Leishmania and Accumulation Differences in Antimony-Resistant Parasites
BROCHU, Christian, JINGYU WANG, ROY, Gaétan, MESSIER, Nadine, WANG, Xiao-Yan, SARAVIA, Nancy G, OUELLETTE, Marc
Published in Antimicrobial Agents and Chemotherapy (01.10.2003)
Published in Antimicrobial Agents and Chemotherapy (01.10.2003)
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Journal Article
Genetic polymorphisms and drug susceptibility in four isolates of Leishmania tropica obtained from Canadian soldiers returning from Afghanistan
Plourde, Marie, Coelho, Adriano, Keynan, Yoav, Larios, Oscar E, Ndao, Momar, Ruest, Annie, Roy, Gaétan, Rubinstein, Ethan, Ouellette, Marc
Published in PLoS neglected tropical diseases (01.01.2012)
Published in PLoS neglected tropical diseases (01.01.2012)
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