Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
Gerlinger, Marco, Horswell, Stuart, Larkin, James, Rowan, Andrew J, Salm, Max P, Varela, Ignacio, Fisher, Rosalie, McGranahan, Nicholas, Matthews, Nicholas, Santos, Claudio R, Martinez, Pierre, Phillimore, Benjamin, Begum, Sharmin, Rabinowitz, Adam, Spencer-Dene, Bradley, Gulati, Sakshi, Bates, Paul A, Stamp, Gordon, Pickering, Lisa, Gore, Martin, Nicol, David L, Hazell, Steven, Futreal, P Andrew, Stewart, Aengus, Swanton, Charles
Published in Nature genetics (01.03.2014)
Published in Nature genetics (01.03.2014)
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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
Gerlinger, Marco, Rowan, Andrew J, Horswell, Stuart, Larkin, James, Endesfelder, David, Gronroos, Eva, Martinez, Pierre, Matthews, Nicholas, Stewart, Aengus, Tarpey, Patrick, Varela, Ignacio, Phillimore, Benjamin, Begum, Sharmin, McDonald, Neil Q, Butler, Adam, Jones, David, Raine, Keiran, Latimer, Calli, Santos, Claudio R, Nohadani, Mahrokh, Eklund, Aron C, Spencer-Dene, Bradley, Clark, Graham, Pickering, Lisa, Stamp, Gordon, Gore, Martin, Szallasi, Zoltan, Downward, Julian, Futreal, P. Andrew, Swanton, Charles
Published in The New England journal of medicine (08.03.2012)
Published in The New England journal of medicine (08.03.2012)
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Replication stress links structural and numerical cancer chromosomal instability
Burrell, Rebecca A., McClelland, Sarah E., Endesfelder, David, Groth, Petra, Weller, Marie-Christine, Shaikh, Nadeem, Domingo, Enric, Kanu, Nnennaya, Dewhurst, Sally M., Gronroos, Eva, Chew, Su Kit, Rowan, Andrew J., Schenk, Arne, Sheffer, Michal, Howell, Michael, Kschischo, Maik, Behrens, Axel, Helleday, Thomas, Bartek, Jiri, Tomlinson, Ian P., Swanton, Charles
Published in Nature (London) (28.02.2013)
Published in Nature (London) (28.02.2013)
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Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution
Dewhurst, Sally M, McGranahan, Nicholas, Burrell, Rebecca A, Rowan, Andrew J, Grönroos, Eva, Endesfelder, David, Joshi, Tejal, Mouradov, Dmitri, Gibbs, Peter, Ward, Robyn L, Hawkins, Nicholas J, Szallasi, Zoltan, Sieber, Oliver M, Swanton, Charles
Published in Cancer discovery (01.02.2014)
Published in Cancer discovery (01.02.2014)
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Systematic Evaluation of the Prognostic Impact and Intratumour Heterogeneity of Clear Cell Renal Cell Carcinoma Biomarkers
Gulati, Sakshi, Martinez, Pierre, Joshi, Tejal, Birkbak, Nicolai Juul, Santos, Claudio R, Rowan, Andrew J, Pickering, Lisa, Gore, Martin, Larkin, James, Szallasi, Zoltan, Bates, Paul A, Swanton, Charles, Gerlinger, Marco
Published in European urology (01.11.2014)
Published in European urology (01.11.2014)
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Chromosomal Instability Confers Intrinsic Multidrug Resistance
LEE, Alvin J. X, ENDESFELDER, David, KSCHISCHO, Maik, SWANTON, Charles, ROWAN, Andrew J, WALTHER, Axel, BIRKBAK, Nicolai J, ANDREW FUTREAL, P, DOWNWARD, Julian, SZALLASI, Zoltan, TOMLINSON, Ian P. M, HOWELL, Michael
Published in Cancer research (Chicago, Ill.) (01.03.2011)
Published in Cancer research (Chicago, Ill.) (01.03.2011)
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BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer
López-García, Carlos, Sansregret, Laurent, Domingo, Enric, McGranahan, Nicholas, Hobor, Sebastijan, Birkbak, Nicolai Juul, Horswell, Stuart, Grönroos, Eva, Favero, Francesco, Rowan, Andrew J., Matthews, Nicholas, Begum, Sharmin, Phillimore, Benjamin, Burrell, Rebecca, Oukrif, Dahmane, Spencer-Dene, Bradley, Kovac, Michal, Stamp, Gordon, Stewart, Aengus, Danielsen, Havard, Novelli, Marco, Tomlinson, Ian, Swanton, Charles
Published in Cancer cell (09.01.2017)
Published in Cancer cell (09.01.2017)
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Expansion of airway basal epithelial cells from primary human non‐small cell lung cancer tumors
Hynds, Robert E., Ben Aissa, Assma, Gowers, Kate H.C., Watkins, Thomas B.K., Bosshard‐Carter, Leticia, Rowan, Andrew J., Veeriah, Selvaraju, Wilson, Gareth A., Quezada, Sergio A., Swanton, Charles, Janes, Sam M.
Published in International journal of cancer (01.07.2018)
Published in International journal of cancer (01.07.2018)
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CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction
Lee, Alvin J. X., Roylance, Rebecca, Sander, Jil, Gorman, Patricia, Endesfelder, David, Kschischo, Maik, Jones, Neil P., East, Philip, Nicke, Barbara, Spassieva, Stefka, Obeid, Lina M., Birkbak, Nicolai Juul, Szallasi, Zoltan, McKnight, Nicole C., Rowan, Andrew J., Speirs, Valerie, Hanby, Andrew M., Downward, Julian, Tooze, Sharon A., Swanton, Charles
Published in The Journal of pathology (01.02.2012)
Published in The Journal of pathology (01.02.2012)
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Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers
GAASENBEEK, Michelle, HOWARTH, Kimberley, CARTER, Nigel P, ROYLANCE, Rebecca R, TOMLINSON, Ian P. M, ROWAN, Andrew J, GORMAN, Patricia A, JONES, Angela, CHAPLIN, Tracy, YING LIU, BICKNELL, David, DAVISON, Eleanor J, FIEGLER, Heike
Published in Cancer research (Chicago, Ill.) (01.04.2006)
Published in Cancer research (Chicago, Ill.) (01.04.2006)
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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
de Bruin, Elza C., McGranahan, Nicholas, Mitter, Richard, Salm, Max, Wedge, David C., Yates, Lucy, Jamal-Hanjani, Mariam, Shafi, Seema, Murugaesu, Nirupa, Rowan, Andrew J., Grönroos, Eva, Muhammad, Madiha A., Horswell, Stuart, Gerlinger, Marco, Varela, Ignacio, Jones, David, Marshall, John, Voet, Thierry, Van Loo, Peter, Rassl, Doris M., Rintoul, Robert C., Janes, Sam M., Lee, Siow-Ming, Forster, Martin, Ahmad, Tanya, Lawrence, David, Falzon, Mary, Capitanio, Arrigo, Harkins, Timothy T., Lee, Clarence C., Tom, Warren, Teefe, Enock, Chen, Shann-Ching, Begum, Sharmin, Rabinowitz, Adam, Phillimore, Benjamin, Spencer-Dene, Bradley, Stamp, Gordon, Szallasi, Zoltan, Matthews, Nik, Stewart, Aengus, Campbell, Peter, Swanton, Charles
Published in Science (American Association for the Advancement of Science) (10.10.2014)
Published in Science (American Association for the Advancement of Science) (10.10.2014)
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Parallel evolution of tumour subclones mimics diversity between tumours
Martinez, Pierre, Birkbak, Nicolai Juul, Gerlinger, Marco, McGranahan, Nicholas, Burrell, Rebecca A, Rowan, Andrew J, Joshi, Tejal, Fisher, Rosalie, Larkin, James, Szallasi, Zoltan, Swanton, Charles
Published in The Journal of pathology (01.08.2013)
Published in The Journal of pathology (01.08.2013)
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Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas
Gerlinger, Marco, Quezada, Sergio A, Peggs, Karl S, Furness, Andrew JS, Fisher, Rosalie, Marafioti, Teresa, Shende, Vishvesh H, McGranahan, Nicholas, Rowan, Andrew J, Hazell, Steven, Hamm, David, Robins, Harlan S, Pickering, Lisa, Gore, Martin, Nicol, David L, Larkin, James, Swanton, Charles
Published in The Journal of pathology (01.12.2013)
Published in The Journal of pathology (01.12.2013)
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Germline Mutations but Not Somatic Changes at the MYH Locus Contribute to the Pathogenesis of Unselected Colorectal Cancers
Halford, Sarah E.R., Rowan, Andrew J., Lipton, Lara, Sieber, Oliver M., Pack, Kevin, Thomas, Huw J.W., Hodgson, Shirley V., Bodmer, Walter F., Tomlinson, Ian P.M.
Published in The American journal of pathology (01.05.2003)
Published in The American journal of pathology (01.05.2003)
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The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours
Sawyer, Elinor J., Hanby, Andrew M., Rowan, Andrew J., Gillett, Cheryl E., Thomas, Rachel E., Poulsom, Richard, Lakhani, Sunil R., Ellis, Ian O., Ellis, Paul, Tomlinson, Ian P. M.
Published in The Journal of pathology (01.04.2002)
Published in The Journal of pathology (01.04.2002)
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Comprehensive Analysis of SMAD4 Mutations and Protein Expression in Juvenile Polyposis : Evidence for a Distinct Genetic Pathway and Polyp Morphology in SMAD4 Mutation Carriers
Woodford-Richens, Kelly L, Rowan, Andrew J, Poulsom, Richard, Bevan, Stephen, Salovaara, Reijo, Aaltonen, Lauri A, Houlston, Richard S, Wright, Nicholas A, Tomlinson, Ian P. M
Published in The American journal of pathology (01.10.2001)
Published in The American journal of pathology (01.10.2001)
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Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
Hiley, Crispin T., Wilson, Gareth A., Birkbak, Nicolai J., Veeriah, Selvaraju, Herrero, Javier, Swanton, Charles, Swanton, Charles, Czyzewska-Khan, Justyna, Gorman, Pat, Wilson, Gareth, Watkins, Thomas B.K., McGranahan, Nicholas, Mitter, Richard, Escudero, Mickael, Rowan, Andrew, Xu, Hang, Turajlic, Samra, Stone, Richard Kevin, Denner, Tamara, Costa, Marta, Phillimore, Ben, Joshi, Kroopa, Furness, Andrew, Ben Aissa, Assma, Wong, Yien Ning Sophia, Quezada, Sergio, Hartley, John A., Lowe, Helen L., Herrero, Javier, Lawrence, David, Falzon, Mary, Borg, Elaine, Marafioti, Teresa, Janes, Sam M., Thakrar, Ricky, Papadatos-Pastos, Dionysis, Choudhary, Junaid, Califano, Raffaele, Taylor, Paul, Crosbie, Phil, Moss, Stuart, Idries, Faiza, Bishop, Paul, Chaturved, Anshuman, Quinn, Anne Marie, Doran, Helen, Leek, Angela, Blackhall, Fiona, Chemi, Francesca, Gulati, Sakshi, Naidu, Babu, Trotter, Simon, Bellamy, Mary, Bancroft, Hollie, Middleton, Gary, Shaw, Jacqui A., Le Quesne, John, Rathinam, Sridhar, Monteiro, William, Marshall, Hilary, Riley, Joan, Primrose, Lindsay, Anand, Girija, Nicolson, Marianne, Palmer, Shirley, Buchan, Keith, Chetty, Mahendran, Edwards, Alison, Morgan, Fiona, Davies, Helen, Verjee, Azmina, MacKenzie, Mairead, Hackshaw, Allan, Smith, Sean, Alzetani, Aiman, Shaw, Emily, Rice, Alexandra, Raubenheimer, Hilgardt, Proli, Chiara, Cufari, Maria Elena, Bhayani, Harshil, Bakar, Yusura, Mensah, Natalie, Ambrose, Lyn, Devaraj, Anand, Chavan, Hema, Lau, Kelvin, Sheaff, Michael, Schmid, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-sellers, Melanie, Prakash, Vineet, Horey, Tracey, Hill, Jennifer, Suvarna, Kim, Keerio, Allah Dino, Feeney, Sarah, Asante-Siaw, Julius, Dessimoz, Christophe
Published in Cell (30.11.2017)
Published in Cell (30.11.2017)
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Clinical features of multiple cutaneous and uterine leiomyomatosis: an underdiagnosed tumor syndrome
Alam, N Afrina, Barclay, Ella, Rowan, Andrew J, Tyrer, Jonathan P, Calonje, Eduardo, Manek, Sanjiv, Kelsell, David, Leigh, Irene, Olpin, Simon, Tomlinson, Ian P M
Published in Archives of dermatology (1960) (01.02.2005)
Published in Archives of dermatology (1960) (01.02.2005)
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Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models
Hynds, Robert E., Huebner, Ariana, Pearce, David R., Hill, Mark S., Akarca, Ayse U., Moore, David A., Ward, Sophia, Gowers, Kate H. C., Karasaki, Takahiro, Al Bakir, Maise, Wilson, Gareth A., Pich, Oriol, Martínez-Ruiz, Carlos, Hossain, A. S. Md Mukarram, Pearce, Simon P., Sivakumar, Monica, Ben Aissa, Assma, Grönroos, Eva, Chandrasekharan, Deepak, Kolluri, Krishna K., Towns, Rebecca, Wang, Kaiwen, Cook, Daniel E., Bosshard-Carter, Leticia, Naceur-Lombardelli, Cristina, Rowan, Andrew J., Veeriah, Selvaraju, Litchfield, Kevin, Crosbie, Philip A. J., Dive, Caroline, Quezada, Sergio A., Janes, Sam M., Jamal-Hanjani, Mariam, Marafioti, Teresa, McGranahan, Nicholas, Swanton, Charles
Published in Nature communications (31.05.2024)
Published in Nature communications (31.05.2024)
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