Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study
Yao, James C, Dr, Fazio, Nicola, MD, Singh, Simron, MD, Buzzoni, Roberto, MD, Carnaghi, Carlo, MD, Wolin, Edward, MD, Tomasek, Jiri, MD, Raderer, Markus, MD, Lahner, Harald, MD, Voi, Maurizio, MD, Pacaud, Lida Bubuteishvili, MD, Rouyrre, Nicolas, MSc, Sachs, Carolin, RN, Valle, Juan W, MD, Fave, Gianfranco Delle, MD, Van Cutsem, Eric, MD, Tesselaar, Margot, MD, Shimada, Yasuhiro, MD, Oh, Do-Youn, MD, Strosberg, Jonathan, MD, Kulke, Matthew H, MD, Pavel, Marianne E, MD
Published in The Lancet (British edition) (05.03.2016)
Published in The Lancet (British edition) (05.03.2016)
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Long-term efficacy and safety of siponimod in patients with secondary progressive multiple sclerosis: Analysis of EXPAND core and extension data up to >5 years
Cree, Bruce AC, Arnold, Douglas L, Fox, Robert J, Gold, Ralf, Vermersch, Patrick, Benedict, Ralph HB, Bar-Or, Amit, Piani-Meier, Daniela, Rouyrre, Nicolas, Ritter, Shannon, Kilaru, Ajay, Karlsson, Goeril, Giovannoni, Gavin, Kappos, Ludwig
Published in Multiple sclerosis (01.09.2022)
Published in Multiple sclerosis (01.09.2022)
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Siponimod: Disentangling disability and relapses in secondary progressive multiple sclerosis
Cree, Bruce AC, Magnusson, Baldur, Rouyrre, Nicolas, Fox, Robert J, Giovannoni, Gavin, Vermersch, Patrick, Bar-Or, Amit, Gold, Ralf, Piani Meier, Daniela, Karlsson, Göril, Tomic, Davorka, Wolf, Christian, Dahlke, Frank, Kappos, Ludwig
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Published in Multiple sclerosis (01.09.2021)
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Phase I Dose Escalation and Pharmacokinetic Study of BI 2536, a Novel Polo-Like Kinase 1 Inhibitor, in Patients With Advanced Solid Tumors
MROSS, Klaus, FROST, Annette, STEINBILD, Simone, HEDBOM, Susanne, RENTSCHLER, Jochen, KAISER, Rolf, ROUYRRE, Nicolas, TROMMESHAUSER, Dirk, HOESI, Cornelia E, MUNZERT, Gerd
Published in Journal of clinical oncology (01.12.2008)
Published in Journal of clinical oncology (01.12.2008)
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Abstract CT-01: BYL719, a next generation PI3K alpha specific inhibitor: Preliminary safety, PK, and efficacy results from the first-in-human study
Juric, Dejan, Rodon, Jordi, Gonzalez-Angulo, Ana M., Burris, Howard A., Bendell, Johanna, Berlin, Jordan D., Middleton, Mark R., Bootle, Douglas, Boehm, Markus, Schmitt, Antonin, Rouyrre, Nicolas, Quadt, Cornelia, Baselga, Jose
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Bayesian inference for a principal stratum estimand to assess the treatment effect in a subgroup characterized by postrandomization event occurrence
Magnusson, Baldur P., Schmidli, Heinz, Rouyrre, Nicolas, Scharfstein, Daniel O.
Published in Statistics in medicine (15.10.2019)
Published in Statistics in medicine (15.10.2019)
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Matching-adjusted indirect treatment comparison of siponimod and other disease modifying treatments in secondary progressive multiple sclerosis
Samjoo, Imtiaz A., Worthington, Evelyn, Haltner, Anja, Cameron, Chris, Nicholas, Richard, Rouyrre, Nicolas, Dahlke, Frank, Adlard, Nicholas
Published in Current medical research and opinion (02.07.2020)
Published in Current medical research and opinion (02.07.2020)
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043 Efficacy of siponimod in secondary progressive multiple sclerosis with active disease: EXPAND study subgroup analysis
Gold, Ralf, Kappos, Ludwig, Bar-Or, Amit, Vermersch, Patrick, Giovannoni, Gavin, Fox, Robert J, Rouyrre, Nicolas, Karlsson, Goril, Cree, Bruce AC
Published in Journal of neurology, neurosurgery and psychiatry (01.06.2022)
Published in Journal of neurology, neurosurgery and psychiatry (01.06.2022)
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Siponimod vs placebo in active secondary progressive multiple sclerosis: a post hoc analysis from the phase 3 EXPAND study
Gold, Ralf, Piani-Meier, Daniela, Kappos, Ludwig, Bar-Or, Amit, Vermersch, Patrick, Giovannoni, Gavin, Fox, Robert J., Arnold, Douglas L., Benedict, Ralph H. B., Penner, Iris-Katharina, Rouyrre, Nicolas, Kilaru, Ajay, Karlsson, Göril, Ritter, Shannon, Dahlke, Frank, Hach, Thomas, Cree, Bruce A. C.
Published in Journal of neurology (01.09.2022)
Published in Journal of neurology (01.09.2022)
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A proof of concept phase II non-inferiority criterion
Neuenschwander, Beat, Rouyrre, Nicolas, Hollaender, Norbert, Zuber, Emmanuel, Branson, Michael
Published in Statistics in medicine (15.06.2011)
Published in Statistics in medicine (15.06.2011)
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Everolimus in ileum neuroendocrine tumours – Authors' reply
Yao, James C, Voi, Maurizio, Rouyrre, Nicolas, Singh, Simron
Published in The Lancet (British edition) (16.07.2016)
Published in The Lancet (British edition) (16.07.2016)
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Stomatitis incidence and its relationship with efficacy: A meta-analysis of everolimus clinical studies
Rugo, Hope S., Yao, James C., Pavel, Marianne, Ravaud, Alain, Franz, David Neal, Taran, Tanya, Gallo, Jorge, Rouyrre, Nicolas, Anak, Oezlem, Motzer, Robert J.
Published in Journal of clinical oncology (10.09.2014)
Published in Journal of clinical oncology (10.09.2014)
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Meta-analysis of stomatitis incidence in everolimus (EVE) clinical studies and its relationship with efficacy
Rugo, Hope S., Yao, James C., Hortobagyi, Gabriel N., Pavel, Marianne E., Franz, David Neal, Ravaud, Alain, Taran, Tanya, Gallo, Jorge, Rouyrre, Nicolas, Anak, Oezlem, Motzer, Robert J.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Everolimus for the treatment of advanced, nonfunctional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study
Yao, James C, Fazio, Nicola, Singh, Simron, Buzzoni, Roberto, Carnaghi, Carlo, Wolin, Edward, Tomasek, Jiri, Raderer, Markus, Lahner, Harald, Voi, Maurizio, Pacaud, Lida Bubuteishvili, Rouyrre, Nicolas, Sachs, Carolin, Valle, Juan W, Fave, Gianfranco Delle, Van Cutsem, Eric, Tesselaar, Margot, Shimada, Yasuhiro, Oh, Do-Youn, Strosberg, Jonathan, Kulke, Matthew H, Pavel, Marianne E
Published in The Lancet (British edition) (17.12.2015)
Published in The Lancet (British edition) (17.12.2015)
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Assessment of nevirapine bioavailability from targeted sites in the human gastrointestinal tract
Macha, Sreeraj, Yong, Chan-Loi, MacGregor, Thomas R, Castles, Mark, Quinson, Anne-Marie, Rouyrre, Nicolas, Wilding, Ian
Published in Journal of clinical pharmacology (01.12.2009)
Published in Journal of clinical pharmacology (01.12.2009)
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Immunogenicity and safety of low-dose intradermal rabies vaccination given during an Expanded Programme on Immunization session in Viet Nam: results of a comparative randomized trial
Lang, Jean, Hoa, Duong Q., Gioi, Nguyen V., Tho, Le Than, Vien, Nguyen C., Rouyrre, Nicolas, Forrat, Remi
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01.03.1999)
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01.03.1999)
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