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Published in Journal of medicinal chemistry (09.06.2016)
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Structure–activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonists
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Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model
Ho, Koc-Kan, Beasley, James R., Belanger, Laura, Black, Darcey, Chan, Jui-Hsiang, Dunn, David, Hu, Bing, Klon, Anthony, Kultgen, Steven G., Ohlmeyer, Michael, Parlato, Susan M., Ray, Peter C., Pham, Quynhchi, Rong, Yajing, Roughton, Andrew L., Walker, Tiffany L., Wright, Jane, Xu, Kai, Xu, Yan, Zhang, Limei, Webb, Maria
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
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Nonionic Analogs of RNA with Dimethylene Sulfone Bridges
Richert, Clemens, Roughton, Andrew L, Benner, Steven A
Published in Journal of the American Chemical Society (15.05.1996)
Published in Journal of the American Chemical Society (15.05.1996)
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Crystal Structure of a Dimethylene Sulfone-Linked Ribodinucleotide Analog
Roughton, Andrew L, Portmann, Stefan, Benner, Steven A, Egli, Martin
Published in Journal of the American Chemical Society (01.07.1995)
Published in Journal of the American Chemical Society (01.07.1995)
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47 HOMODETIC CYCLIC PEPTIDES TARGETING 47 1NTEGRIN
MORSHED MONZUR M, VAZQUEZ MANUEL PEREZ, ROUGHTON ANDREW, HICKEY JENNIFER L, KAFAL ADAM PAUL
Year of Publication 07.06.2023
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Year of Publication 07.06.2023
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Predicting cyclic peptide chemical shifts using quantum mechanical calculations
Zaretsky, Serge, Hickey, Jennifer L., St. Denis, Megan A., Scully, Conor C.G., Roughton, Andrew L., Tantillo, Dean J., Lodewyk, Michael W., Yudin, Andrei K.
Published in Tetrahedron (21.10.2014)
Published in Tetrahedron (21.10.2014)
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α4β7 인테그린을 타겟팅하는 호모데틱 사이클릭 펩타이드
MORSHED MONZUR M, VAZQUEZ MANUEL PEREZ, ROUGHTON ANDREW, HICKEY JENNIFER L, KAFAL ADAM PAUL
Year of Publication 12.02.2020
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Year of Publication 12.02.2020
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Stereocontrolled construction of 1,7-dimethyl A.B.C.[6.6.6] tricycles. Part II. Transannular Diels-Alder reaction of 14-membered macrocycles containing cis-dienophiles
Xu, Yao-Chang, Roughton, Andrew L, Soucy, Pierre, Goldstein, Solo, Deslongchamps, Pierre
Published in Canadian journal of chemistry (01.08.1993)
Published in Canadian journal of chemistry (01.08.1993)
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Stereocontrolled construction of 1,7-dimethyl A.B.C.[6.6.6] tricycles. Part I. Transannular Diels-Alder reactions of 14-membered macrocycles containing trans-dienophiles
Xu, Yao-Chang, Roughton, Andrew L, Plante, Raymond, Goldstein, Solo, Deslongchamps, Pierre
Published in Canadian journal of chemistry (01.08.1993)
Published in Canadian journal of chemistry (01.08.1993)
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Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity
Lukkarila, Julie L., da Silva, Sara R., Ali, Mohsin, Shahani, Vijay M., Xu, G. Wei, Berman, Judd, Roughton, Andrew, Dhe-Paganon, Sirano, Schimmer, Aaron D., Gunning, Patrick T.
Published in ACS medicinal chemistry letters (11.08.2011)
Published in ACS medicinal chemistry letters (11.08.2011)
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α4β7 인테그린을 표적으로 하는 고리형 펩타이드
ROUGHTON ANDREW L, POUPART MARC ANDRE, VAZQUEZ MANUEL PEREZ, YANG GAOQIANG, GILLARD JAMES, MORSHED M. MONZUR, HICKEY JENNIFER L, KAFAL ADAM PAUL, PATEL NARENDRA, CHAKKA SAI KUMAR
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Year of Publication 28.08.2018
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Cyclization of protected N-acylhydroxyguanidine to 3-amino-1,2,4-oxadiazole
Côté, Jamie B., Roughton, Andrew, Nasielski, Joanna, Wilson, Jeff, You, Ji Chang, Berman, Judd M.
Published in Tetrahedron letters (02.11.2011)
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Discovery of potent, soluble and orally active TRPV1 antagonists. Structure–activity relationships of a series of isoxazoles
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Published in Bioorganic & medicinal chemistry letters (01.08.2011)
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
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Imidazolylpyrimidine based CXCR2 chemokine receptor antagonists
Ho, Koc-Kan, Auld, Douglas S., Bohnstedt, Adolph C., Conti, Paolo, Dokter, Wim, Erickson, Shawn, Feng, Daming, Inglese, Jim, Kingsbury, Celia, Kultgen, Steven G., Liu, Rong-Qiang, Masterson, Christopher M., Ohlmeyer, Michael, Rong, Yajing, Rooseboom, Martijn, Roughton, Andrew, Samama, Philippe, Smit, Martin-Jan, Son, Ellen, van der Louw, Jaap, Vogel, Gerard, Webb, Maria, Wijkmans, Jac, You, Ming
Published in Bioorganic & medicinal chemistry letters (15.05.2006)
Published in Bioorganic & medicinal chemistry letters (15.05.2006)
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COMPOSITIONS AND METHODS FOR INHIBITION OF EXPRESSION OF ANGIOTENSINOGEN (AGT) GENES
FANG, Zhou, ZHANG, Tianbu, MONTERO, Saul Martinez, ROUGHTON, Andrew L, LIN, Luping, PARATHATH, Sajesh, YANG, Jing
Year of Publication 12.09.2024
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A Statistical-Based Approach To Assessing the Fidelity of Combinatorial Libraries Encoded with Electrophoric Molecular Tags. Development and Application of Tag Decode-Assisted Single Bead LC/MS Analysis
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Published in Journal of combinatorial chemistry (01.11.2000)
Published in Journal of combinatorial chemistry (01.11.2000)
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Cyclic peptides multimers targeting α4β7 integrin
Vazquez, Manuel Perez, Chakka, Sai Kumar, Morshed, Mohammed Monzur, Roughton, Andrew, Hickey, Jennifer L, Patel, Narendrakumar B, Kafal, Adam Paul
Year of Publication 03.09.2024
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Year of Publication 03.09.2024
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