The Complement Inhibitor Eculizumab in Paroxysmal Nocturnal Hemoglobinuria
Hillmen, Peter, Young, Neal S, Schubert, Jörg, Brodsky, Robert A, Socié, Gerard, Muus, Petra, Röth, Alexander, Szer, Jeffrey, Elebute, Modupe O, Nakamura, Ryotaro, Browne, Paul, Risitano, Antonio M, Hill, Anita, Schrezenmeier, Hubert, Fu, Chieh-Lin, Maciejewski, Jaroslaw, Rollins, Scott A, Mojcik, Christopher F, Rother, Russell P, Luzzatto, Lucio
Published in The New England journal of medicine (21.09.2006)
Published in The New England journal of medicine (21.09.2006)
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Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice
McGonigal, Rhona, Rowan, Edward G., Greenshields, Kay N., Halstead, Susan K., Humphreys, Peter D., Rother, Russell P., Furukawa, Koichi, Willison, Hugh J.
Published in Brain (London, England : 1878) (01.07.2010)
Published in Brain (London, England : 1878) (01.07.2010)
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Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization
HILL, Anita, ROTHER, Russell P, ARNOLD, Louise, KELLY, Richard, CULLEN, Matthew J, RICHARDS, Stephen J, HILLMEN, Peter
Published in Haematologica (Roma) (01.04.2010)
Published in Haematologica (Roma) (01.04.2010)
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Long-term efficacy of the complement inhibitor eculizumab in cold agglutinin disease
Röth, Alexander, Hüttmann, Andreas, Rother, Russell P., Dührsen, Ulrich, Philipp, Thomas
Published in Blood (16.04.2009)
Published in Blood (16.04.2009)
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The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab
Kelly, Richard, Arnold, Louise, Richards, Stephen, Hill, Anita, Bomken, Charlotte, Hanley, John, Loughney, Andrew, Beauchamp, Jon, Khursigara, Gus, Rother, Russell P., Chalmers, Elizabeth, Fyfe, Andrew, Fitzsimons, Edward, Nakamura, Ryotaro, Gaya, Anna, Risitano, Antonio M., Schubert, Jörg, Norfolk, Derek, Simpson, Nigel, Hillmen, Peter
Published in British journal of haematology (01.05.2010)
Published in British journal of haematology (01.05.2010)
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Sustained response and long-term safety of eculizumab in paroxysmal nocturnal hemoglobinuria
Hill, Anita, Hillmen, Peter, Richards, Stephen J., Elebute, Dupe, Marsh, Judith C., Chan, Jason, Mojcik, Christopher F., Rother, Russell P.
Published in Blood (01.10.2005)
Published in Blood (01.10.2005)
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Gastrointestinal Ischemia-Reperfusion Injury Is Lectin Complement Pathway Dependent without Involving C1q
Hart, Melanie L, Ceonzo, Kathleen A, Shaffer, Lisa A, Takahashi, Kazue, Rother, Russell P, Reenstra, Wende R, Buras, Jon A, Stahl, Gregory L
Published in The Journal of immunology (1950) (15.05.2005)
Published in The Journal of immunology (1950) (15.05.2005)
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Inhibition of Terminal Complement Components in Presensitized Transplant Recipients Prevents Antibody-Mediated Rejection Leading to Long-Term Graft Survival and Accommodation
Wang, Hao, Arp, Jacqueline, Liu, Weihua, Faas, Susan J, Jiang, Jifu, Gies, David R, Ramcharran, Siobhan, Garcia, Bertha, Zhong, Robert, Rother, Russell P
Published in Journal of Immunology (01.10.2007)
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Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease
Ataga, Kenneth I, Kutlar, Abdullah, Kanter, Julie, Liles, Darla, Cancado, Rodolfo, Friedrisch, João, Guthrie, Troy H, Knight-Madden, Jennifer, Alvarez, Ofelia A, Gordeuk, Victor R, Gualandro, Sandra, Colella, Marina P, Smith, Wally R, Rollins, Scott A, Stocker, Jonathan W, Rother, Russell P
Published in The New England journal of medicine (02.02.2017)
Published in The New England journal of medicine (02.02.2017)
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Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria
Brodsky, Robert A., Young, Neal S., Antonioli, Elisabetta, Risitano, Antonio M., Schrezenmeier, Hubert, Schubert, Jörg, Gaya, Anna, Coyle, Luke, de Castro, Carlos, Fu, Chieh-Lin, Maciejewski, Jaroslaw P., Bessler, Monica, Kroon, Henk-André, Rother, Russell P., Hillmen, Peter
Published in Blood (15.02.2008)
Published in Blood (15.02.2008)
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Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria
Hillmen, Peter, Muus, Petra, Dührsen, Ulrich, Risitano, Antonio M., Schubert, Jörg, Luzzatto, Lucio, Schrezenmeier, Hubert, Szer, Jeffrey, Brodsky, Robert A., Hill, Anita, Socié, Gerard, Bessler, Monica, Rollins, Scott A., Bell, Leonard, Rother, Russell P., Young, Neal S.
Published in Blood (01.12.2007)
Published in Blood (01.12.2007)
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Long‐term effect of the complement inhibitor eculizumab on kidney function in patients with paroxysmal nocturnal hemoglobinuria
Hillmen, Peter, Elebute, Modupe, Kelly, Richard, Urbano‐Ispizua, Alvaro, Hill, Anita, Rother, Russell P., Khursigara, Gus, Fu, Chieh‐Lin, Omine, Mitsuhiro, Browne, Paul, Rosse, Wendell
Published in American journal of hematology (01.08.2010)
Published in American journal of hematology (01.08.2010)
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Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model
Halstead, Susan K., Zitman, Femke M. P., Humphreys, Peter D., Greenshields, Kay, Verschuuren, Jan J., Jacobs, Bart C., Rother, Russell P., Plomp, Jaap J., Willison, Hugh J.
Published in Brain (London, England : 1878) (01.05.2008)
Published in Brain (London, England : 1878) (01.05.2008)
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Effect of eculizumab on haemolysis‐associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria
Hill, Anita, Rother, Russell P., Wang, Xunde, Morris, Jr, Sidney M., Quinn‐Senger, Kerry, Kelly, Richard, Richards, Stephen J., Bessler, Monica, Bell, Leonard, Hillmen, Peter, Gladwin, Mark T.
Published in British journal of haematology (01.05.2010)
Published in British journal of haematology (01.05.2010)
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Effect of Eculizumab on Hemolysis and Transfusion Requirements in Patients with Paroxysmal Nocturnal Hemoglobinuria
Hillmen, Peter, Hall, Claire, Marsh, Judith C.W, Elebute, Modupe, Bombara, Michael P, Petro, Beth E, Cullen, Matthew J, Richards, Stephen J, Rollins, Scott A, Mojcik, Christopher F, Rother, Russell P
Published in The New England journal of medicine (05.02.2004)
Published in The New England journal of medicine (05.02.2004)
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Complement Regulator CD59 Protects Against Atherosclerosis by Restricting the Formation of Complement Membrane Attack Complex
Wu, Gongxiong, Hu, Weiguo, Shahsafaei, Aliakbar, Song, Wenping, Dobarro, Martin, Sukhova, Galina K, Bronson, Rod R, Shi, Guo-ping, Rother, Russell P, Halperin, Jose A, Qin, Xuebin
Published in Circulation research (27.02.2009)
Published in Circulation research (27.02.2009)
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