Amylin: Pharmacology, Physiology, and Clinical Potential
Hay, Debbie L, Chen, Steve, Lutz, Thomas A, Parkes, David G, Roth, Jonathan D
Published in Pharmacological reviews (01.07.2015)
Published in Pharmacological reviews (01.07.2015)
Get full text
Journal Article
Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment
Clapper, Jason R, Hendricks, Michelle D, Gu, Guibao, Wittmer, Carrie, Dolman, Carrie S, Herich, John, Athanacio, Jennifer, Villescaz, Christiane, Ghosh, Soumitra S, Heilig, Joseph S, Lowe, Carolyn, Roth, Jonathan D
Published in American journal of physiology: Gastrointestinal and liver physiology (01.10.2013)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.10.2013)
Get full text
Journal Article
Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice
Trevaskis, James L, Griffin, Peter S, Wittmer, Carrie, Neuschwander-Tetri, Brent A, Brunt, Elizabeth M, Dolman, Carrie S, Erickson, Mary R, Napora, James, Parkes, David G, Roth, Jonathan D
Published in American journal of physiology: Gastrointestinal and liver physiology (15.04.2012)
Published in American journal of physiology: Gastrointestinal and liver physiology (15.04.2012)
Get full text
Journal Article
FXR activation by obeticholic acid or nonsteroidal agonists induces a human-like lipoprotein cholesterol change in mice with humanized chimeric liver
Papazyan, Romeo, Liu, Xueqing, Liu, Jingwen, Dong, Bin, Plummer, Emily M., Lewis, Ronald D., Roth, Jonathan D., Young, Mark A.
Published in Journal of lipid research (01.06.2018)
Published in Journal of lipid research (01.06.2018)
Get full text
Journal Article
Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies
Roth, Jonathan D, Roland, Barbara L, Cole, Rebecca L, Trevaskis, James L, Weyer, Christian, Koda, Joy E, Anderson, Christen M, Parkes, David G, Baron, Alain D
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
Get full text
Journal Article
Mechanisms of Amylin/Leptin Synergy in Rodent Models
Turek, Victoria F, Trevaskis, James L, Levin, Barry E, Dunn-Meynell, Ambrose A, Irani, Boman, Gu, Guibao, Wittmer, Carrie, Griffin, Peter S, Vu, Calvin, Parkes, David G, Roth, Jonathan D
Published in Endocrinology (Philadelphia) (01.01.2010)
Published in Endocrinology (Philadelphia) (01.01.2010)
Get full text
Journal Article
Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms
Trevaskis, James L, Coffey, Todd, Cole, Rebecca, Lei, Chunli, Wittmer, Carrie, Walsh, Brandon, Weyer, Christian, Koda, Joy, Baron, Alain D, Parkes, David G, Roth, Jonathan D
Published in Endocrinology (Philadelphia) (01.11.2008)
Published in Endocrinology (Philadelphia) (01.11.2008)
Get full text
Journal Article
Effects of amylin and bupropion/naltrexone on food intake and body weight are interactive in rodent models
Clapper, Jason R., Athanacio, Jennifer, Wittmer, Carrie, Griffin, Pete S., D'Souza, Lawrence, Parkes, David G., Roth, Jonathan D.
Published in European journal of pharmacology (05.01.2013)
Published in European journal of pharmacology (05.01.2013)
Get full text
Journal Article
Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH
Roth, Jonathan D, Veidal, Sanne S, Fensholdt, Louise K D, Rigbolt, Kristoffer T G, Papazyan, Romeo, Nielsen, Jens Christian, Feigh, Michael, Vrang, Niels, Young, Mark, Jelsing, Jacob, Adorini, Luciano, Hansen, Henrik H
Published in Scientific reports (21.06.2019)
Published in Scientific reports (21.06.2019)
Get full text
Journal Article
GLP‐1R and amylin agonism in metabolic disease: complementary mechanisms and future opportunities
Roth, Jonathan D, Erickson, Mary R, Chen, Steve, Parkes, David G
Published in British journal of pharmacology (01.05.2012)
Published in British journal of pharmacology (01.05.2012)
Get full text
Journal Article
Antiobesity Effects of the β-Cell Hormone Amylin in Diet-Induced Obese Rats: Effects on Food Intake, Body Weight, Composition, Energy Expenditure, and Gene Expression
Roth, Jonathan D, Hughes, Heather, Kendall, Eric, Baron, Alain D, Anderson, Christen M
Published in Endocrinology (Philadelphia) (01.12.2006)
Published in Endocrinology (Philadelphia) (01.12.2006)
Get full text
Journal Article
Insights into amylin–leptin synergy
Trevaskis, James L, Parkes, David G, Roth, Jonathan D
Published in Trends in endocrinology and metabolism (01.08.2010)
Published in Trends in endocrinology and metabolism (01.08.2010)
Get full text
Journal Article
Simultaneous quantification of the glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) receptor agonists in rodent plasma by on-line solid phase extraction and LC–MS/MS
Wang, Yan, Roth, Jonathan D., Taylor, Steven W.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.04.2014)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.04.2014)
Get full text
Journal Article
Noradrenergic neurons of the area postrema mediate amylin's hypophagic action
Potes, Catarina S, Turek, Victoria F, Cole, Rebecca L, Vu, Calvin, Roland, Barbara L, Roth, Jonathan D, Riediger, Thomas, Lutz, Thomas A
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.08.2010)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.08.2010)
Get full text
Journal Article
Enhanced Amylin-Mediated Body Weight Loss in Estradiol-Deficient Diet-Induced Obese Rats
Trevaskis, James L, Turek, Victoria F, Wittmer, Carrie, Griffin, Peter S, Wilson, Julie K, Reynolds, James M, Zhao, Yu, Mack, Christine M, Parkes, David G, Roth, Jonathan D
Published in Endocrinology (Philadelphia) (01.12.2010)
Published in Endocrinology (Philadelphia) (01.12.2010)
Get full text
Journal Article
“Weighing in” on synergy: Preclinical research on neurohormonal anti-obesity combinations
Roth, Jonathan D, Trevaskis, James L, Turek, Victoria F, Parkes, David G
Published in Brain research (02.09.2010)
Published in Brain research (02.09.2010)
Get full text
Journal Article
Combination Therapy with Amylin and Peptide YY[3–36] in Obese Rodents: Anorexigenic Synergy and Weight Loss Additivity
Roth, Jonathan D, Coffey, Todd, Jodka, Carolyn M, Maier, Holly, Athanacio, Jennifer R, Mack, Christine M, Weyer, Christian, Parkes, David G
Published in Endocrinology (Philadelphia) (01.12.2007)
Published in Endocrinology (Philadelphia) (01.12.2007)
Get full text
Journal Article