Recombinant nematode anticoagulant protein c2, an inhibitor of tissue factor/factor VIIa, attenuates coagulation and the interleukin‐10 response in human endotoxemia
De Pont, A. C. J. M., Moons, A. H. M., De Jonge, E., Meijers, J. C. M., Vlasuk, G. P., Rote, W. E., Büller, H. R., Van Der Poll, T., Levi, M.
Published in Journal of thrombosis and haemostasis (01.01.2004)
Published in Journal of thrombosis and haemostasis (01.01.2004)
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Potent and Selective Thrombin Inhibitors Incorporating the Constrained Arginine Mimic l-3-Piperidyl(N-guanidino)alanine at P1
Levy, Odile E, Semple, J. Edward, Lim, Michael L, Reiner, John, Rote, William E, Dempsey, Erin, Richard, Brigitte M, Zhang, Erli, Tulinsky, Al, Ripka, William C, Nutt, Ruth F
Published in Journal of medicinal chemistry (08.11.1996)
Published in Journal of medicinal chemistry (08.11.1996)
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Prevention of experimental carotid artery thrombosis by applaggin
W E Rote, D X Mu, R A Roncinske, A L Frelinger, 3rd, B R Lucchesi
Published in The Journal of pharmacology and experimental therapeutics (01.11.1993)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.1993)
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Platelet GPIIb/IIIa receptor inhibition by SC-49992 prevents thrombosis and rethrombosis in the canine carotid artery
Rote, William E, Werns, Steven W, Davis, James H, Feigen, Larry P, Kilgore, Kenneth S, Lucchesi, Benedict R
Published in Cardiovascular research (01.03.1993)
Published in Cardiovascular research (01.03.1993)
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Orally effective CVS-1123 prevents coronary artery thrombosis in the conscious dog
COUSINS, G. R, FRIEDRICHS, G. S, SUDO, Y, REBELLO, S. S, ROTE, W. E, VLASUK, G. P, NOLAN, T. G, MENDOZA, C, LUCCHESI, B. R
Published in Circulation (New York, N.Y.) (01.10.1996)
Published in Circulation (New York, N.Y.) (01.10.1996)
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Journal Article
Activation of Coagulation by Administration of Recombinant Factor VIIa Elicits Interleukin 6 (IL-6) and IL-8 Release in Healthy Human Subjects
de Jonge, Evert, Friederich, Philip W, Vlasuk, George P, Rote, William E, Vroom, Margaretha B, Levi, Marcel, van der Poll, Tom
Published in Clinical and Diagnostic Laboratory Immunology (01.05.2003)
Published in Clinical and Diagnostic Laboratory Immunology (01.05.2003)
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The role of CD11/CD18 integrins in the reverse passive Arthus reaction in rat dermal tissue
Rote, William E., Dempsey, Erin, Maki, Steve, Vlasuk, George P., Moyle, Matthew
Published in Journal of leukocyte biology (01.02.1996)
Published in Journal of leukocyte biology (01.02.1996)
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Journal Article
Ability of recombinant factor VIIa to generate thrombin during inhibition of tissue factor in human subjects
FRIEDERICH, Philip W, LEVI, Marcel, BAUER, Kenneth A, VLASUK, George P, ROTE, William E, BREEDERVELD, Daan, KELLER, Tijmen, SPATARO, Marco, BARZEGAR, Samad, BÜLLER, Harry R
Published in Circulation (New York, N.Y.) (29.05.2001)
Published in Circulation (New York, N.Y.) (29.05.2001)
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Prevention of thrombosis and rethrombosis and enhancement of the thrombolytic actions of recombinant tissue‐type plasminogen activator in the canine heart by DMP728, a glycoprotein IIb/IIIa antagonist
Lucchessi, Benedict R., Rote, William E., Driscoll, Edward M., Mu, Dun‐Xue
Published in British journal of pharmacology (01.12.1994)
Published in British journal of pharmacology (01.12.1994)
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Inhibition of the Tissue Factor/Factor VIIa Pathway Does Not Influence the Inflammatory or Antibacterial Response to Abdominal Sepsis Induced by Escherichia coli in Mice
Weijer, Sebastian, Schoenmakers, Saskia H. H. F., Florquin, Sandrine, Levi, Marcel, Vlasuk, George P., Rote, William E., Reitsma, Pieter H., Spek, Arnold, Poll, Tom van der
Published in The Journal of infectious diseases (15.06.2004)
Published in The Journal of infectious diseases (15.06.2004)
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Nitroglycerin inhibits experimental thrombosis and reocclusion after thrombolysis
Werns, Steven W., Rote, William E., Davis, James H., Guevara, Tristan, Lucchesi, Benedict R.
Published in The American heart journal (01.04.1994)
Published in The American heart journal (01.04.1994)
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Journal Article
Antithrombotic Efficacy of a Recombinant Nematode Anticoagulant Peptide (rNAP5) in Canine Models of Thrombosis after Single Subcutaneous Administration
Rebello, S S, Blank, H S, Rote, W E, Vlasuk, G P, Lucchesi, B R
Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Design and synthesis of a novel class of thrombin inhibitors incorporating heterocyclic dipeptide surrogates
Tamura, Susan Y., Edward Semple, J., Reiner, John E., Goldman, Erick A., Brunck, Terence K., Lim-Wilby, Marguerita S., Carpenter, Stephen H., Rote, William E., Oldeshulte, Gerard L., Richard, Brigitte M., Nutt, Ruth F., Ripka, William C.
Published in Bioorganic & medicinal chemistry letters (17.06.1997)
Published in Bioorganic & medicinal chemistry letters (17.06.1997)
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Chimeric 7E3 prevents carotid artery thrombosis in cynomolgus monkeys
Rote, W E, Nedelman, M A, Mu, D X, Manley, P J, Weisman, H, Cunningham, M R, Lucchesi, B R
Published in Stroke (1970) (01.06.1994)
Published in Stroke (1970) (01.06.1994)
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