A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal
Sun, James X, He, Yuting, Sanford, Eric, Montesion, Meagan, Frampton, Garrett M, Vignot, Stéphane, Soria, Jean-Charles, Ross, Jeffrey S, Miller, Vincent A, Stephens, Phil J, Lipson, Doron, Yelensky, Roman
Published in PLoS computational biology (07.02.2018)
Published in PLoS computational biology (07.02.2018)
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Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study
Sicklick, Jason K, Kato, Shumei, Okamura, Ryosuke, Schwaederle, Maria, Hahn, Michael E, Williams, Casey B, De, Pradip, Krie, Amy, Piccioni, David E, Miller, Vincent A, Ross, Jeffrey S, Benson, Adam, Webster, Jennifer, Stephens, Philip J, Lee, J Jack, Fanta, Paul T, Lippman, Scott M, Leyland-Jones, Brian, Kurzrock, Razelle
Published in Nature medicine (01.05.2019)
Published in Nature medicine (01.05.2019)
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Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study
Necchi, Andrea, Anichini, Andrea, Raggi, Daniele, Briganti, Alberto, Massa, Simona, Lucianò, Roberta, Colecchia, Maurizio, Giannatempo, Patrizia, Mortarini, Roberta, Bianchi, Marco, Farè, Elena, Monopoli, Francesco, Colombo, Renzo, Gallina, Andrea, Salonia, Andrea, Messina, Antonella, Ali, Siraj M, Madison, Russell, Ross, Jeffrey S, Chung, Jon H, Salvioni, Roberto, Mariani, Luigi, Montorsi, Francesco
Published in Journal of clinical oncology (01.12.2018)
Published in Journal of clinical oncology (01.12.2018)
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Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients
Serebriiskii, Ilya G, Connelly, Caitlin, Frampton, Garrett, Newberg, Justin, Cooke, Matthew, Miller, Vince, Ali, Siraj, Ross, Jeffrey S, Handorf, Elizabeth, Arora, Sanjeevani, Lieu, Christopher, Golemis, Erica A, Meyer, Joshua E
Published in Nature communications (19.08.2019)
Published in Nature communications (19.08.2019)
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Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers
Pozdeyev, Nikita, Gay, Laurie M, Sokol, Ethan S, Hartmaier, Ryan, Deaver, Kelsi E, Davis, Stephanie, French, Jena D, Borre, Pierre Vanden, LaBarbera, Daniel V, Tan, Aik-Choon, Schweppe, Rebecca E, Fishbein, Lauren, Ross, Jeffrey S, Haugen, Bryan R, Bowles, Daniel W
Published in Clinical cancer research (01.07.2018)
Published in Clinical cancer research (01.07.2018)
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Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
Chalmers, Zachary R, Connelly, Caitlin F, Fabrizio, David, Gay, Laurie, Ali, Siraj M, Ennis, Riley, Schrock, Alexa, Campbell, Brittany, Shlien, Adam, Chmielecki, Juliann, Huang, Franklin, He, Yuting, Sun, James, Tabori, Uri, Kennedy, Mark, Lieber, Daniel S, Roels, Steven, White, Jared, Otto, Geoffrey A, Ross, Jeffrey S, Garraway, Levi, Miller, Vincent A, Stephens, Phillip J, Frampton, Garrett M
Published in Genome medicine (19.04.2017)
Published in Genome medicine (19.04.2017)
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Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies
Necchi, Andrea, Raggi, Daniele, Gallina, Andrea, Madison, Russell, Colecchia, Maurizio, Lucianò, Roberta, Montironi, Rodolfo, Giannatempo, Patrizia, Farè, Elena, Pederzoli, Filippo, Bandini, Marco, Bianchi, Marco, Colombo, Renzo, Gandaglia, Giorgio, Fossati, Nicola, Marandino, Laura, Capitanio, Umberto, Dehò, Federico, Ali, Siraj M., Chung, Jon H., Ross, Jeffrey S., Salonia, Andrea, Briganti, Alberto, Montorsi, Francesco
Published in European urology (01.04.2020)
Published in European urology (01.04.2020)
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Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer
Mehnert, Janice M, Panda, Anshuman, Zhong, Hua, Hirshfield, Kim, Damare, Sherri, Lane, Katherine, Sokol, Levi, Stein, Mark N, Rodriguez-Rodriquez, Lorna, Kaufman, Howard L, Ali, Siraj, Ross, Jeffrey S, Pavlick, Dean C, Bhanot, Gyan, White, Eileen P, DiPaola, Robert S, Lovell, Ann, Cheng, Jonathan, Ganesan, Shridar
Published in The Journal of clinical investigation (01.06.2016)
Published in The Journal of clinical investigation (01.06.2016)
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The distribution of BRAF gene fusions in solid tumors and response to targeted therapy
Ross, Jeffrey S., Wang, Kai, Chmielecki, Juliann, Gay, Laurie, Johnson, Adrienne, Chudnovsky, Jacob, Yelensky, Roman, Lipson, Doron, Ali, Siraj M, Elvin, Julia A., Vergilio, Jo‐Anne, Roels, Steven, Miller, Vincent A, Nakamura, Brooke N., Gray, Adam, Wong, Michael K, Stephens, Philip J
Published in International journal of cancer (15.02.2016)
Published in International journal of cancer (15.02.2016)
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Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers
Singhi, Aatur D., George, Ben, Greenbowe, Joel R., Chung, Jon, Suh, James, Maitra, Anirban, Klempner, Samuel J., Hendifar, Andrew, Milind, Javle M., Golan, Talia, Brand, Randall E., Zureikat, Amer H., Roy, Somak, Schrock, Alexa B., Miller, Vincent A., Ross, Jeffrey S., Ali, Siraj M., Bahary, Nathan
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2019)
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Advances and limits of using population genetics to understand local adaptation
Tiffin, Peter, Ross-Ibarra, Jeffrey
Published in Trends in ecology & evolution (Amsterdam) (01.12.2014)
Published in Trends in ecology & evolution (Amsterdam) (01.12.2014)
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Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3
Ross, Jeffrey S., Fakih, Marwan, Ali, Siraj M., Elvin, Julia A., Schrock, Alexa B., Suh, James, Vergilio, Jo‐Anne, Ramkissoon, Shakti, Severson, Eric, Daniel, Sugganth, Fabrizio, David, Frampton, Garrett, Sun, James, Miller, Vincent A., Stephens, Philip J., Gay, Laurie M.
Published in Cancer (01.04.2018)
Published in Cancer (01.04.2018)
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Impact of EML4-ALK Variant on Resistance Mechanisms and Clinical Outcomes in ALK-Positive Lung Cancer
Lin, Jessica J, Zhu, Viola W, Yoda, Satoshi, Yeap, Beow Y, Schrock, Alexa B, Dagogo-Jack, Ibiayi, Jessop, Nicholas A, Jiang, Ginger Y, Le, Long P, Gowen, Kyle, Stephens, Philip J, Ross, Jeffrey S, Ali, Siraj M, Miller, Vincent A, Johnson, Melissa L, Lovly, Christine M, Hata, Aaron N, Gainor, Justin F, Iafrate, Anthony J, Shaw, Alice T, Ou, Sai-Hong Ignatius
Published in Journal of clinical oncology (20.04.2018)
Published in Journal of clinical oncology (20.04.2018)
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Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions
Lovly, Christine M, Gupta, Abha, Lipson, Doron, Otto, Geoff, Brennan, Tina, Chung, Catherine T, Borinstein, Scott C, Ross, Jeffrey S, Stephens, Philip J, Miller, Vincent A, Coffin, Cheryl M
Published in Cancer discovery (01.08.2014)
Published in Cancer discovery (01.08.2014)
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Impact of Molecular Subtyping and Immune Infiltration on Pathological Response and Outcome Following Neoadjuvant Pembrolizumab in Muscle-invasive Bladder Cancer
Necchi, Andrea, Raggi, Daniele, Gallina, Andrea, Ross, Jeffrey S., Farè, Elena, Giannatempo, Patrizia, Marandino, Laura, Colecchia, Maurizio, Lucianò, Roberta, Bianchi, Marco, Colombo, Renzo, Salonia, Andrea, Gandaglia, Giorgio, Fossati, Nicola, Bandini, Marco, Pederzoli, Filippo, Capitanio, Umberto, Montorsi, Francesco, de Jong, Joep J., Dittamore, Ryan, Liu, Yang, Davicioni, Elai, Boormans, Joost L., Briganti, Alberto, Black, Peter C., Gibb, Ewan A.
Published in European urology (01.06.2020)
Published in European urology (01.06.2020)
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ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer
Pietrantonio, Filippo, Di Nicolantonio, Federica, Schrock, Alexa B, Lee, Jeeyun, Tejpar, Sabine, Sartore-Bianchi, Andrea, Hechtman, Jaclyn F, Christiansen, Jason, Novara, Luca, Tebbutt, Niall, Fucà, Giovanni, Antoniotti, Carlotta, Kim, Seung Tae, Murphy, Danielle, Berenato, Rosa, Morano, Federica, Sun, James, Min, Bosun, Stephens, Philip J, Chen, Marissa, Lazzari, Luca, Miller, Vincent A, Shoemaker, Robert, Amatu, Alessio, Milione, Massimo, Ross, Jeffrey S, Siena, Salvatore, Bardelli, Alberto, Ali, Siraj M, Falcone, Alfredo, de Braud, Filippo, Cremolini, Chiara
Published in JNCI : Journal of the National Cancer Institute (01.12.2017)
Published in JNCI : Journal of the National Cancer Institute (01.12.2017)
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Understanding variants of unknown significance and classification of genomic alterations
Pavlick, Dean C, Frampton, Garrett M, Ross, Jeffrey R
Published in The oncologist (Dayton, Ohio) (05.08.2024)
Published in The oncologist (Dayton, Ohio) (05.08.2024)
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