Mono-Oxidation of Bidentate Bis-phosphines in Catalyst Activation: Kinetic and Mechanistic Studies of a Pd/Xantphos-Catalyzed C–H Functionalization
Ji, Yining, Plata, R. Erik, Regens, Christopher S, Hay, Michael, Schmidt, Michael, Razler, Thomas, Qiu, Yuping, Geng, Peng, Hsiao, Yi, Rosner, Thorsten, Eastgate, Martin D, Blackmond, Donna G
Published in Journal of the American Chemical Society (21.10.2015)
Published in Journal of the American Chemical Society (21.10.2015)
Get full text
Journal Article
Highly Efficient Asymmetric Synthesis of Sitagliptin
Hansen, Karl B, Hsiao, Yi, Xu, Feng, Rivera, Nelo, Clausen, Andrew, Kubryk, Michele, Krska, Shane, Rosner, Thorsten, Simmons, Bryon, Balsells, Jaume, Ikemoto, Nori, Sun, Yongkui, Spindler, Felix, Malan, Christophe, Grabowski, Edward J. J, Armstrong, Joseph D
Published in Journal of the American Chemical Society (01.07.2009)
Published in Journal of the American Chemical Society (01.07.2009)
Get full text
Journal Article
An Efficient Asymmetric Synthesis of an Estrogen Receptor Modulator by Sulfoxide-Directed Borane Reduction
Song, Zhiguo J., King, Anthony O., Waters, Marjorie S., Lang, Fengrui, Zewge, Daniel, Bio, Matthew, Leazer, Johnnie L., Javadi, Gary, Kassim, Amude, Tschaen, David M., Reamer, Robert A., Rosner, Thorsten, Chilenski, Jennifer R., Mathre, David J., Volante, R. P., Tillyer, Richard, Trost, Barry M.
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2004)
Get full text
Journal Article
Asymmetric synthesis of ENT-03, the predicted mammalian ortholog of the dog fish shark aminosterol trodusquemine (MSI-1436)
Kinney, William A., Phillip Cox, D., Jones, Stephen R., Hessler, Edward J., Karnes, Harold A., Fevig, Thomas L., Hewitt, Bradley D., Sullivan, Ryan, Tseng, Nai-Wen, Pasion, Edward, Beale, Thomas, Rosner, Thorsten, Crouch, Ian T., D’Ambrosio, Stephen, Wade, Peter, Chen, Hui, Gao, Qi, Thompson, Andrew S., Muzzio, Miguel, Barbut, Denise, Zasloff, Michael A.
Published in Tetrahedron letters (19.09.2024)
Published in Tetrahedron letters (19.09.2024)
Get full text
Journal Article
Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes
Beutner, Gregory, Carrasquillo, Ronald, Geng, Peng, Hsiao, Yi, Huang, Eric C, Janey, Jacob, Katipally, Kishta, Kolotuchin, Sergei, La Porte, Thomas, Lee, Andrew, Lobben, Paul, Lora-Gonzalez, Federico, Mack, Brendan, Mudryk, Boguslaw, Qiu, Yuping, Qian, Xinhua, Ramirez, Antonio, Razler, Thomas M, Rosner, Thorsten, Shi, Zhongping, Simmons, Eric, Stevens, Jason, Wang, Jianji, Wei, Carolyn, Wisniewski, Steven R, Zhu, Ye
Published in Organic letters (06.07.2018)
Published in Organic letters (06.07.2018)
Get full text
Journal Article
C–H Arylation in the Formation of a Complex Pyrrolopyridine, the Commercial Synthesis of the Potent JAK2 Inhibitor, BMS-911543
Fox, Richard J, Cuniere, Nicolas L, Bakrania, Lopa, Wei, Carolyn, Strotman, Neil A, Hay, Michael, Fanfair, Dayne, Regens, Christopher, Beutner, Gregory L, Lawler, Michael, Lobben, Paul, Soumeillant, Maxime C, Cohen, Benjamin, Zhu, Keming, Skliar, Dimitri, Rosner, Thorsten, Markwalter, Chester E, Hsiao, Yi, Tran, Kristy, Eastgate, Martin D
Published in Journal of organic chemistry (19.04.2019)
Published in Journal of organic chemistry (19.04.2019)
Get full text
Journal Article
Enantioselective Synthesis of a γ‑Secretase Modulator via Vinylogous Dynamic Kinetic Resolution
Strotman, Neil A, Ramirez, Antonio, Simmons, Eric M, Soltani, Omid, Parsons, Andrew T, Fan, Yu, Sawyer, James R, Rosner, Thorsten, Janey, Jacob M, Tran, Kristy, Li, Jun, La Cruz, Thomas E, Pathirana, Charles, Ng, Alicia T, Deerberg, Joerg
Published in Journal of organic chemistry (21.09.2018)
Published in Journal of organic chemistry (21.09.2018)
Get full text
Journal Article
Correction to “Highly Efficient Asymmetric Synthesis of Sitagliptin”
Hansen, Karl B, Hsiao, Yi, Xu, Feng, Rivera, Nelo, Clausen, Andrew, Kubryk, Michele, Krska, Shane, Rosner, Thorsten, Simmons, Bryon, Balsells, Jaume, Ikemoto, Nori, Sun, Yongkui, Spindler, Felix, Malan, Christophe, Grabowski, Edward J. J
Published in Journal of the American Chemical Society (05.08.2020)
Published in Journal of the American Chemical Society (05.08.2020)
Get full text
Journal Article
Combining Solid-State and Solution Calorimetry for the Gibbs Free Energy Calculation of Polymorphs To Determine the Relative Stability and Solubility
Hsieh, Daniel S, Roberts, Daniel, Rosner, Thorsten, Rosenbaum, Tamar, Lai, Chiajen, Gao, Qi
Published in Crystal growth & design (06.01.2016)
Published in Crystal growth & design (06.01.2016)
Get full text
Journal Article
Development of a scalable palladium-catalyzed α-arylation process for the synthesis of a CGRP antagonist
Desai, Lopa V., Hay, Michael B., Leahy, David K., Wei, Carolyn, Fanfair, Dayne, Rosner, Thorsten, Hsiao, Yi
Published in Tetrahedron (08.07.2013)
Published in Tetrahedron (08.07.2013)
Get full text
Journal Article
Highly Efficient Synthesis of β-Amino Acid Derivatives via Asymmetric Hydrogenation of Unprotected Enamines
Hsiao, Yi, Rivera, Nelo R, Rosner, Thorsten, Krska, Shane W, Njolito, Eugenia, Wang, Fang, Sun, Yongkui, Armstrong, Joseph D, Grabowski, Edward J. J, Tillyer, Richard D, Spindler, Felix, Malan, Christophe
Published in Journal of the American Chemical Society (18.08.2004)
Published in Journal of the American Chemical Society (18.08.2004)
Get full text
Journal Article
Efficient and Scalable Enantioselective Synthesis of a CGRP Antagonist
Leahy, David K, Fan, Yu, Desai, Lopa V, Chan, Collin, Zhu, Jason, Luo, Guanglin, Chen, Ling, Hanson, Ronald L, Sugiyama, Masano, Rosner, Thorsten, Cuniere, Nicolas, Guo, Zhiwei, Hsiao, Yi, Gao, Qi
Published in Organic letters (21.09.2012)
Published in Organic letters (21.09.2012)
Get full text
Journal Article
Kinetic Studies of Heck Coupling Reactions Using Palladacycle Catalysts: Experimental and Kinetic Modeling of the Role of Dimer Species
Rosner, Thorsten, Le Bars, Joel, Pfaltz, Andreas, Blackmond, Donna G
Published in Journal of the American Chemical Society (07.03.2001)
Published in Journal of the American Chemical Society (07.03.2001)
Get full text
Journal Article
Discovery of Indazoles as Potent, Orally Active Dual Neurokinin 1 Receptor Antagonists and Serotonin Transporter Inhibitors for the Treatment of Depression
Degnan, Andrew P, Tora, George O, Huang, Hong, Conlon, David A, Davis, Carl D, Hanumegowda, Umesh M, Hou, Xiaoping, Hsiao, Yi, Hu, Joanna, Krause, Rudolph, Li, Yu-Wen, Newton, Amy E, Pieschl, Rick L, Raybon, Joseph, Rosner, Thorsten, Sun, Jung-Hui, Taber, Matthew T, Taylor, Sarah J, Wong, Michael K, Zhang, Huiping, Lodge, Nicholas J, Bronson, Joanne J, Macor, John E, Gillman, Kevin W
Published in ACS chemical neuroscience (21.12.2016)
Published in ACS chemical neuroscience (21.12.2016)
Get full text
Journal Article
On the mechanism of an asymmetric alpha,beta-unsaturated carboxylic acid hydrogenation: Application to the synthesis of a PGD(2) receptor antagonist
Tellers, David M., McWilliams, J. Christopher, Humphrey, Guy, Journet, Michel, DiMichele, Lisa, Hinksmon, Joseph, McKeown, Arlene E., Rosner, Thorsten, Sun, Yongkui, Tillyer, Richard D.
Published in Journal of the American Chemical Society (27.12.2006)
Published in Journal of the American Chemical Society (27.12.2006)
Get full text
Journal Article
On the Mechanism of an Asymmetric α,β-Unsaturated Carboxylic Acid Hydrogenation: Application to the Synthesis of a PGD2 Receptor Antagonist
Tellers, David M, McWilliams, J. Christopher, Humphrey, Guy, Journet, Michel, DiMichele, Lisa, Hinksmon, Joseph, McKeown, Arlene E, Rosner, Thorsten, Sun, Yongkui, Tillyer, Richard D
Published in Journal of the American Chemical Society (27.12.2006)
Published in Journal of the American Chemical Society (27.12.2006)
Get full text
Journal Article