Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner
De Silva, Enoli, Devine, Dana V, Jan, Eric, Roskelley, Calvin D, Kim, Hugh
Published in Biochemical journal (30.11.2022)
Published in Biochemical journal (30.11.2022)
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Journal Article
Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease
Refaeli, Ido, Hughes, Michael R., Wong, Alvin Ka-Wai, Bissonnette, Mei Lin Z., Roskelley, Calvin D., Wayne Vogl, A., Barbour, Sean J., Freedman, Benjamin S., McNagny, Kelly M.
Published in Scientific reports (10.06.2020)
Published in Scientific reports (10.06.2020)
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Journal Article
Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation
Cait, Jessica, Hughes, Michael R., Zeglinski, Matthew R., Chan, Allen W., Osterhof, Sabrina, Scott, R. Wilder, Hernaez, Diana Canals, Cait, Alissa, Vogl, A. Wayne, Bernatchez, Pascal, Underhill, T. Michael, Granville, David J., Murphy, Timothy H., Roskelley, Calvin D., McNagny, Kelly M.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
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Journal Article
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation
Freeman, Spencer A, Lei, Victor, Dang-Lawson, May, Mizuno, Kensaku, Roskelley, Calvin D, Gold, Michael R
Published in The Journal of immunology (1950) (01.12.2011)
Published in The Journal of immunology (1950) (01.12.2011)
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Journal Article
CD44 Loss Disrupts Lung Lipid Surfactant Homeostasis and Exacerbates Oxidized Lipid-Induced Lung Inflammation
Dong, Yifei, Arif, Arif A, Guo, Jian, Ha, Zongyi, Lee-Sayer, Sally S M, Poon, Grace F T, Dosanjh, Manisha, Roskelley, Calvin D, Huan, Tao, Johnson, Pauline
Published in Frontiers in immunology (30.01.2020)
Published in Frontiers in immunology (30.01.2020)
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Journal Article
Loukoumasomes Are Distinct Subcellular Structures from Rods and Rings and Are Structurally Associated with MAP2 and the Nuclear Envelope in Retinal Cells
Noble, Jake W, Hunter, Diana V, Roskelley, Calvin D, Chan, Edward K L, Mills, Julia
Published in PloS one (31.10.2016)
Published in PloS one (31.10.2016)
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Journal Article
Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy
Snyder, Kimberly A, Hughes, Michael R, Hedberg, Bradley, Brandon, Jill, Hernaez, Diana Canals, Bergqvist, Peter, Cruz, Frederic, Po, Kelvin, Graves, Marcia L, Turvey, Michelle E, Nielsen, Julie S, Wilkins, John A, McColl, Shaun R, Babcook, John S, Roskelley, Calvin D, McNagny, Kelly M
Published in Breast cancer research : BCR (27.03.2015)
Published in Breast cancer research : BCR (27.03.2015)
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Journal Article
Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor
Freeman, Spencer A, Jaumouillé, Valentin, Choi, Kate, Hsu, Brian E, Wong, Harikesh S, Abraham, Libin, Graves, Marcia L, Coombs, Daniel, Roskelley, Calvin D, Das, Raibatak, Grinstein, Sergio, Gold, Michael R
Published in Nature communications (03.02.2015)
Published in Nature communications (03.02.2015)
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Journal Article
A premalignant cell-based model for functionalization and classification of PTEN variants
Chao, Jesse T, Hollman, Rocio, Meyers, Warren M, Meili, Fabian, Matreyek, Kenneth A, Dean, Pamela, Fowler, Douglas M, Haas, Kurt, Roskelley, Calvin D, Loewen, Christopher J R
Published in Cancer research (Chicago, Ill.) (01.07.2020)
Published in Cancer research (Chicago, Ill.) (01.07.2020)
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Journal Article
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma
Tognon, Cristina, Knezevich, Stevan R, Huntsman, David, Roskelley, Calvin D, Melnyk, Natalya, Mathers, Joan A, Becker, Laurence, Carneiro, Fatima, MacPherson, Nicol, Horsman, Doug, Poremba, Christopher, Sorensen, Poul H.B
Published in Cancer cell (01.11.2002)
Published in Cancer cell (01.11.2002)
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Journal Article
Inflammation-Induced Metastatic Colonization of the Lung Is Facilitated by Hepatocyte Growth Factor-Secreting Monocyte-Derived Macrophages
Arif, Arif A, Huang, Yu-Hsuan, Freeman, Spencer A, Atif, Jawairia, Dean, Pamela, Lai, Jacqueline C Y, Blanchet, Marie-Renee, Wiegand, Kimberly C, McNagny, Kelly M, Underhill, T Michael, Gold, Michael R, Johnson, Pauline, Roskelley, Calvin D
Published in Molecular cancer research (01.12.2021)
Published in Molecular cancer research (01.12.2021)
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Journal Article
Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor
Freeman, Spencer A, Christian, Sonja, Austin, Pamela, Iu, Irene, Graves, Marcia L, Huang, Lin, Tang, Shuo, Coombs, Daniel, Gold, Michael R, Roskelley, Calvin D
Published in Journal of cell science (01.01.2017)
Published in Journal of cell science (01.01.2017)
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Journal Article
Antibody-Drug Conjugates Targeting Tumor-Specific Mucin Glycoepitopes
Brassard, Julyanne, Hughes, Michael R, Roskelley, Calvin D, McNagny, Kelly M
Published in Frontiers in bioscience (Landmark. Print) (04.11.2022)
Published in Frontiers in bioscience (Landmark. Print) (04.11.2022)
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Journal Article
A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma
Brassard, Julyanne, Hughes, Michael R, Dean, Pamela, Hernaez, Diana Canals, Thornton, Shelby, Banville, Allyson C, Smazynski, Julian, Warren, Mary, Zhang, Kevin, Milne, Katy, Gilks, C Blake, Mes-Masson, Anne-Marie, Huntsman, David G, Nelson, Brad H, Roskelley, Calvin D, McNagny, Kelly M
Published in Frontiers in oncology (2023)
Published in Frontiers in oncology (2023)
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Journal Article
The CD34-related molecule podocalyxin is a potent inducer of microvillus formation
Nielsen, Julie S, Graves, Marcia L, Chelliah, Shierley, Vogl, A Wayne, Roskelley, Calvin D, McNagny, Kelly M
Published in PloS one (21.02.2007)
Published in PloS one (21.02.2007)
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Journal Article
The cell surface mucin podocalyxin regulates collective breast tumor budding
Graves, Marcia L, Cipollone, Jane A, Austin, Pamela, Bell, Erin M, Nielsen, Julie S, Gilks, C Blake, McNagny, Kelly M, Roskelley, Calvin D
Published in Breast cancer research : BCR (22.01.2016)
Published in Breast cancer research : BCR (22.01.2016)
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Journal Article
Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models
Canals Hernaez, Diana, Hughes, Michael R, Li, Yicong, Mainero Rocca, Ilaria, Dean, Pamela, Brassard, Julyanne, Bell, Erin M, Samudio, Ismael, Mes-Masson, Anne-Marie, Narimatsu, Yoshiki, Clausen, Henrik, Blixt, Ola, Roskelley, Calvin D, McNagny, Kelly M
Published in Frontiers in oncology (04.05.2022)
Published in Frontiers in oncology (04.05.2022)
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Journal Article