Progranulin as a therapeutic target in neurodegenerative diseases
Rhinn, Herve, Tatton, Nadine, McCaughey, Stella, Kurnellas, Michael, Rosenthal, Arnon
Published in Trends in pharmacological sciences (Regular ed.) (01.08.2022)
Published in Trends in pharmacological sciences (Regular ed.) (01.08.2022)
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Journal Article
Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model
Wang, Shoutang, Mustafa, Meer, Yuede, Carla M, Salazar, Santiago Viveros, Kong, Philip, Long, Hua, Ward, Michael, Siddiqui, Omer, Paul, Robert, Gilfillan, Susan, Ibrahim, Adiljan, Rhinn, Hervé, Tassi, Ilaria, Rosenthal, Arnon, Schwabe, Tina, Colonna, Marco
Published in The Journal of experimental medicine (07.09.2020)
Published in The Journal of experimental medicine (07.09.2020)
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Journal Article
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Hong, Soyon, Beja-Glasser, Victoria F., Nfonoyim, Bianca M., Frouin, Arnaud, Li, Shaomin, Ramakrishnan, Saranya, Merry, Katherine M., Shi, Qiaoqiao, Rosenthal, Arnon, Barres, Ben A., Lemere, Cynthia A., Selkoe, Dennis J., Stevens, Beth
Published in Science (American Association for the Advancement of Science) (06.05.2016)
Published in Science (American Association for the Advancement of Science) (06.05.2016)
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Journal Article
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis
Cignarella, Francesca, Filipello, Fabia, Bollman, Bryan, Cantoni, Claudia, Locca, Alberto, Mikesell, Robert, Manis, Melissa, Ibrahim, Adiljan, Deng, Li, Benitez, Bruno A., Cruchaga, Carlos, Licastro, Danilo, Mihindukulasuriya, Kathie, Harari, Oscar, Buckland, Michael, Holtzman, David M., Rosenthal, Arnon, Schwabe, Tina, Tassi, Ilaria, Piccio, Laura
Published in Acta neuropathologica (01.10.2020)
Published in Acta neuropathologica (01.10.2020)
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Journal Article
Cloud computing: A new business paradigm for biomedical information sharing
Rosenthal, Arnon, Mork, Peter, Li, Maya Hao, Stanford, Jean, Koester, David, Reynolds, Patti
Published in Journal of biomedical informatics (01.04.2010)
Published in Journal of biomedical informatics (01.04.2010)
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Journal Article
Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis
Eroglu, Çagla, Allen, Nicola J., Susman, Michael W., O'Rourke, Nancy A., Park, Chan Young, Özkan, Engin, Chakraborty, Chandrani, Mulinyawe, Sara B., Annis, Douglas S., Huberman, Andrew D., Green, Eric M., Lawler, Jack, Dolmetsch, Ricardo, Garcia, K. Christopher, Smith, Stephen J., Luo, Z. David, Rosenthal, Arnon, Mosher, Deane F., Barres, Ben A.
Published in Cell (01.10.2009)
Published in Cell (01.10.2009)
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Journal Article
Targeting Progranulin as an Immuno-Neurology Therapeutic Approach
Boylan, Maria A, Pincetic, Andrew, Romano, Gary, Tatton, Nadine, Kenkare-Mitra, Sara, Rosenthal, Arnon
Published in International journal of molecular sciences (01.11.2023)
Published in International journal of molecular sciences (01.11.2023)
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Journal Article
Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia
Kurnellas, Michael, Mitra, Ananya, Schwabe, Tina, Paul, Robert, Arrant, Andrew E, Roberson, Erik D, Ward, Michael, Yeh, Felix, Long, Hua, Rosenthal, Arnon
Published in Journal of translational medicine (15.06.2023)
Published in Journal of translational medicine (15.06.2023)
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Journal Article
Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer's disease
Long, Hua, Simmons, Adam, Mayorga, Arthur, Burgess, Brady, Nguyen, Tuan, Budda, Balasubrahmanyam, Rychkova, Anna, Rhinn, Herve, Tassi, Ilaria, Ward, Michael, Yeh, Felix, Schwabe, Tina, Paul, Robert, Kenkare-Mitra, Sara, Rosenthal, Arnon
Published in Alzheimer's research & therapy (23.10.2024)
Published in Alzheimer's research & therapy (23.10.2024)
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Journal Article
Novel class of pain drugs based on antagonism of NGF
Hefti, Franz F., Rosenthal, Arnon, Walicke, Patricia A., Wyatt, Sean, Vergara, German, Shelton, David L., Davies, Alun M.
Published in Trends in pharmacological sciences (Regular ed.) (01.02.2006)
Published in Trends in pharmacological sciences (Regular ed.) (01.02.2006)
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Journal Article
Phase 1 study of latozinemab in progranulin‐associated frontotemporal dementia
Ward, Michael, Carter, Lawrence P., Huang, Julie Y., Maslyar, Daniel, Budda, Balasubrahmanyam, Paul, Robert, Rosenthal, Arnon
Published in Alzheimer's & dementia : translational research & clinical interventions (01.01.2024)
Published in Alzheimer's & dementia : translational research & clinical interventions (01.01.2024)
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Journal Article
eTuner : tuning schema matching software using synthetic scenarios
LEE, Yoonkyong, SAYYADIAN, Mayssam, DOAN, Anhai, ROSENTHAL, Amon S
Published in The VLDB journal (01.01.2007)
Published in The VLDB journal (01.01.2007)
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Conference Proceeding
Journal Article
Passive immunotherapy against A beta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage
Wilcock, Donna M, Rojiani, Amyn, Rosenthal, Arnon, Subbarao, Sangeetha, Freeman, Melissa J, Gordon, Marcia N, Morgan, Dave
Published in Journal of neuroinflammation (08.12.2004)
Published in Journal of neuroinflammation (08.12.2004)
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Journal Article
Passive Amyloid Immunotherapy Clears Amyloid and Transiently Activates Microglia in a Transgenic Mouse Model of Amyloid Deposition
Wilcock, Donna M, Rojiani, Amyn, Rosenthal, Arnon, Levkowitz, Gil, Subbarao, Sangeetha, Alamed, Jennifer, Wilson, David, Wilson, Nedda, Freeman, Melissa J, Gordon, Marcia N, Morgan, Dave
Published in The Journal of neuroscience (07.07.2004)
Published in The Journal of neuroscience (07.07.2004)
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Journal Article
Molecular Basis for Catecholaminergic Neuron Diversity
Grimm, Jan, Mueller, Anne, Hefti, Franz, Rosenthal, Arnon, Bargmann, Cornelia I.
Published in Proceedings of the National Academy of Sciences - PNAS (21.09.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (21.09.2004)
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Journal Article
FGF and Shh Signals Control Dopaminergic and Serotonergic Cell Fate in the Anterior Neural Plate
Ye, Weilan, Shimamura, Kenji, Rubenstein, John L.R, Hynes, Mary A, Rosenthal, Arnon
Published in Cell (29.05.1998)
Published in Cell (29.05.1998)
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Journal Article
TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice
Tsao, David, Thomsen, Heather Koenig, Chou, Joyce, Stratton, Jennifer, Hagen, Michael, Loo, Carole, Garcia, Carlos, Sloane, David L, Rosenthal, Arnon, Lin, John C
Published in Endocrinology (Philadelphia) (01.03.2008)
Published in Endocrinology (Philadelphia) (01.03.2008)
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Journal Article
The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons
Lin, John C, Rosenthal, Arnon, Ho, Wei-Hsien, Gurney, Austin
Published in Nature neuroscience (01.12.2003)
Published in Nature neuroscience (01.12.2003)
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Journal Article