Suppression of Parvalbumin Interneuron Activity in the Prefrontal Cortex Recapitulates Features of Impaired Excitatory/Inhibitory Balance and Sensory Processing in Schizophrenia
Toader, Oana, von Heimendahl, Moritz, Schuelert, Niklas, Nissen, Wiebke, Rosenbrock, Holger
Published in Schizophrenia bulletin (08.07.2020)
Published in Schizophrenia bulletin (08.07.2020)
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Journal Article
Symptomatic and preventive effects of the novel phosphodiesterase-9 inhibitor BI 409306 in an immune-mediated model of neurodevelopmental disorders
Scarborough, Joseph, Mattei, Daniele, Dorner-Ciossek, Cornelia, Sand, Michael, Arban, Roberto, Rosenbrock, Holger, Richetto, Juliet, Meyer, Urs
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2021)
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2021)
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Journal Article
Quantitative electroencephalography parameters as neurophysiological biomarkers of schizophrenia-related deficits: A Phase II substudy of patients treated with iclepertin (BI 425809)
Schultheis, Christian, Rosenbrock, Holger, Mack, Salome Rebecca, Vinisko, Richard, Schuelert, Niklas, Plano, Andrea, Süssmuth, Sigurd D.
Published in Translational psychiatry (11.08.2022)
Published in Translational psychiatry (11.08.2022)
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Journal Article
A comprehensive analysis of auditory event‐related potentials and network oscillations in an NMDA receptor antagonist mouse model using a novel wireless recording technology
Schuelert, Niklas, Dorner‐Ciossek, Cornelia, Brendel, Michael, Rosenbrock, Holger
Published in Physiological reports (01.08.2018)
Published in Physiological reports (01.08.2018)
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Journal Article
Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator
Rosenbrock, Holger, Kramer, Gert, Hobson, Scott, Koros, Eliza, Grundl, Marc, Grauert, Matthias, Reymann, Klaus G., Schröder, Ulrich H.
Published in European journal of pharmacology (10.08.2010)
Published in European journal of pharmacology (10.08.2010)
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Journal Article
Effect of chronic intermittent restraint stress on hippocampal expression of marker proteins for synaptic plasticity and progenitor cell proliferation in rats
Rosenbrock, Holger, Koros, Eliza, Bloching, Anita, Podhorna, Jana, Borsini, Franco
Published in Brain research (08.04.2005)
Published in Brain research (08.04.2005)
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Journal Article
Development of the novel GlyT1 inhibitor, iclepertin (BI 425809), for the treatment of cognitive impairment associated with schizophrenia
Rosenbrock, Holger, Desch, Michael, Wunderlich, Glen
Published in European archives of psychiatry and clinical neuroscience (01.10.2023)
Published in European archives of psychiatry and clinical neuroscience (01.10.2023)
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Journal Article
Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons
Singec, Ilyas, Knoth, Rolf, Ditter, Margarethe, Hagemeyer, Christoph E., Rosenbrock, Holger, Frotscher, Michael, Volk, Benedikt
Published in Journal of comparative neurology (1911) (14.10.2002)
Published in Journal of comparative neurology (1911) (14.10.2002)
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Journal Article
The Glycine Transport Inhibitor Bi 425809 Restores Translatable EEG Deficits in an Acute Mouse Model for Schizophrenia-Related Sensory Processing and Cortical Network Dysfunction
Schuelert, Niklas, Dorner-Ciossek, Cornelia, Rosenbrock, Holger
Published in Biological psychiatry (1969) (01.05.2021)
Published in Biological psychiatry (1969) (01.05.2021)
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Journal Article
Neuroimaging Biomarkers for Drug Discovery and Development in Schizophrenia
Preller, Katrin H., Scholpp, Joachim, Wunder, Andreas, Rosenbrock, Holger
Published in Biological psychiatry (1969) (15.10.2024)
Published in Biological psychiatry (1969) (15.10.2024)
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Journal Article
Effects of the glycine transporter-1 inhibitor iclepertin (BI 425809) on sensory processing, neural network function, and cognition in animal models related to schizophrenia
Rosenbrock, Holger, Dorner-Ciossek, Cornelia, Giovannini, Riccardo, Schmid, Bernhard, Schuelert, Niklas
Published in The Journal of pharmacology and experimental therapeutics (01.08.2022)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2022)
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Journal Article
Reply to the Letter to the Editor regarding; Not mismatch negativity modulation of sensory N1 is measured
Schuelert, Niklas, Chen-Engerer, Hsing-Jung, Rosenbrock, Holger
Published in Neuroscience (21.02.2023)
Published in Neuroscience (21.02.2023)
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Journal Article
P376. Preclinical Pharmacological Characterization of the Selective NR2b Negative Allosteric Modulator BI 1569912 With Potential to Treat MDD
Just, Stefan, Ceci, Angelo, Ferger, Boris, Draheim, Henning, Giovannini, Riccardo, Rosenbrock, Holger, Dorner-Ciossek, Cornelia
Published in Biological psychiatry (1969) (01.05.2022)
Published in Biological psychiatry (1969) (01.05.2022)
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Journal Article
Pro-cognitive effects of the GlyT1 inhibitor Bitopertin in rodents
Deiana, Serena, Hauber, Wolfgang, Munster, Alexandra, Sommer, Susanne, Ferger, Boris, Marti, Anelise, Schmid, Bernhard, Dorner-Ciossek, Cornelia, Rosenbrock, Holger
Published in European journal of pharmacology (15.11.2022)
Published in European journal of pharmacology (15.11.2022)
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Journal Article
Preclinical validation of the micropipette-guided drug administration (MDA) method in the maternal immune activation model of neurodevelopmental disorders
Scarborough, Joseph, Mueller, Flavia, Arban, Roberto, Dorner-Ciossek, Cornelia, Weber-Stadlbauer, Ulrike, Rosenbrock, Holger, Meyer, Urs, Richetto, Juliet
Published in Brain, behavior, and immunity (01.08.2020)
Published in Brain, behavior, and immunity (01.08.2020)
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Journal Article