Effects of Cytochrome P450 3A4 Induction and Inhibition on the Pharmacokinetics of BI 425809, a Novel Glycine Transporter 1 Inhibitor
Desch, Michael, Wunderlich, Glen, Goettel, Markus, Goetz, Sophia, Liesenfeld, Karl-Heinz, Chan, Tom S., Rosenbrock, Holger, Sennewald, Regina, Link, Jasmin, Keller, Sascha, Wind, Sven
Published in European journal of drug metabolism and pharmacokinetics (01.01.2022)
Published in European journal of drug metabolism and pharmacokinetics (01.01.2022)
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sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca2+ homeostasis and CREB1-signaling
Hesse, Raphael, von Einem, Bjoern, Wagner, Franziska, Bott, Patricia, Schwanzar, Daniel, Jackson, Rosemary J., Föhr, Karl Josef, Lausser, Ludwig, Kroker, Katja S., Proepper, Christian, Walther, Paul, Kestler, Hans A., Spires-Jones, Tara L., Boeckers, Tobias, Rosenbrock, Holger, von Arnim, Christine A.F.
Published in Experimental neurology (01.06.2018)
Published in Experimental neurology (01.06.2018)
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Journal Article
Upscaling of hiPS Cell–Derived Neurons for High-Throughput Screening
Traub, Stefanie, Stahl, Heiko, Rosenbrock, Holger, Simon, Eric, Heilker, Ralf
Published in SLAS discovery (01.03.2017)
Published in SLAS discovery (01.03.2017)
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Journal Article
PT745. Targeting the dopamine 1 receptor or its downstream signalling by inhibiting phosphodiesterase-1 improves cognitive performance
Pekcec, Anton, Schülert, Niklas, Giovannini, Riccardo, Pfau, Roland, Stierstorfer, Birgit, Hobson, Scott, Rosenbrock, Holger
Published in The international journal of neuropsychopharmacology (01.06.2016)
Published in The international journal of neuropsychopharmacology (01.06.2016)
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Journal Article
PM537. GPR52 agonists show pro-cognitive properties
von Heimendahl, Moritz, Arban, Roberto, Deiana, Serena, Hobson, Scott, Rosenbrock, Holger, Schülert, Niklas
Published in The international journal of neuropsychopharmacology (01.06.2016)
Published in The international journal of neuropsychopharmacology (01.06.2016)
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Journal Article
P4‐010: Improving Cognitive Function in Rodents Via Increasing Glycine Levels in Brain by the Novel Glycine Transporter‐1 Inhibitor BI 425809
Rosenbrock, Holger, Giovannini, Riccardo, Schmid, Bernhard, Kramer, Gert, Arban, Roberto, Dorner-Ciossek, Cornelia, Wunderlich, Glen
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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Journal Article
IMPROVING COGNITIVE FUNCTION IN RODENTS VIA INCREASING GLYCINE LEVELS IN BRAIN BY THE NOVEL GLYCINE TRANSPORTER-1 INHIBITOR BI 425809
Rosenbrock, Holger, Giovannini, Riccardo, Schmid, Bernhard, Kramer, Gert, Arban, Roberto, Dorner-Ciossek, Cornelia, Wunderlich, Glen
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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Journal Article
A randomized Phase II trial evaluating efficacy, safety, and tolerability of oral BI 409306 in attenuated psychosis syndrome: Design and rationale
Keefe, Richard S. E., Woods, Scott W., Cannon, Tyrone D., Ruhrmann, Stephan, Mathalon, Daniel H., McGuire, Philip, Rosenbrock, Holger, Daniels, Kristen, Cotton, Daniel, Roy, Dooti, Pollentier, Stephane, Sand, Michael
Published in Early intervention in psychiatry (01.10.2021)
Published in Early intervention in psychiatry (01.10.2021)
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Journal Article
Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression
Hesse, Raphael, Lausser, Ludwig, Gummert, Pauline, Schmid, Florian, Wahler, Anke, Schnack, Cathrin, Kroker, Katja S, Otto, Markus, Tumani, Hayrettin, Kestler, Hans A, Rosenbrock, Holger, von Arnim, Christine A F
Published in Alzheimer's research & therapy (09.03.2017)
Published in Alzheimer's research & therapy (09.03.2017)
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Journal Article
P2‐310: Improving synaptic plasticity and cognitive function in rodents by the novel phosphodiesterase 9A inhibitor bi 409306
Rosenbrock, Holger, Marti, Anelise, Koros, Eliza, Runge, Frank, Fuchs, Holger, Giovannini, Riccardo, Dorner-Ciossek, Cornelia
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Journal Article
Improving synaptic plasticity and cognitive function in rodents by the novel phosphodiesterase 9A inhibitor bi 409306
Rosenbrock, Holger, Marti, Anelise, Koros, Eliza, Runge, Frank, Fuchs, Holger, Giovannini, Riccardo, Dorner-Ciossek, Cornelia
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Journal Article
Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation
Fernández-Fernández, Diego, Dorner-Ciossek, Cornelia, Kroker, Katja S., Rosenbrock, Holger
Published in Journal of neuroscience research (01.03.2016)
Published in Journal of neuroscience research (01.03.2016)
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Journal Article
S25. EFFECTS OF METABOTROPIC GLUTAMATE 2/3 RECEPTOR ACTIVATION ON DEFICITS OF NEURAL NETWORK FUNCTION INDUCED BY OPTOGENETIC INHIBITION OF PARVALBUMIN-POSITIVE INTERNEURONS IN THE MOUSE PREFRONTAL CORTEX
Toader, Oana, Nissen, Wiebke, Schülert, Niklas, Heimendahl, Moritz Von, Rosenbrock, Holger
Published in Schizophrenia bulletin (09.04.2019)
Published in Schizophrenia bulletin (09.04.2019)
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Journal Article
Globular and Protofibrillar Aβ Aggregates Impair Neurotransmission by Different Mechanisms
Moreth, Jens, Kroker, Katja S, Schwanzar, Daniel, Schnack, Cathrin, von Arnim, Christine A. F, Hengerer, Bastian, Rosenbrock, Holger, Kussmaul, Lothar
Published in Biochemistry (Easton) (26.02.2013)
Published in Biochemistry (Easton) (26.02.2013)
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Journal Article
Poster #M15 PRE-SYNAPTIC LOCALIZATION OF PDE2 ENZYME AND PHARMACOLOGICAL CHARACTERIZATION OF THE PDE2 INHIBITOR PF-999 IN MODELS RELATED TO COGNITIVE SYMPTOMS OF SCHIZOPHRENIA
Rosenbrock, Holger, Kroker, Katja S, Bertani, Barbara, Stierstorfer, Birgit, Dorner-Ciossek, Cornelia, Arban, Roberto
Published in Schizophrenia research (01.04.2014)
Published in Schizophrenia research (01.04.2014)
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P1‐027: BEHAVIORAL CHARACTERIZATION OF TG2576 MICE IN TOUCHSCREEN TASKS TARGETING DIFFERENT ASPECTS OF LEARNING AND MEMORY
Dorner‐Ciossek, Cornelia, Delotterie, David, Mathis, Chantal, Cassel, Jean‐Christophe, Rosenbrock, Holger, Marti, Anelise
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
BEHAVIORAL CHARACTERIZATION OF TG2576 MICE IN TOUCHSCREEN TASKS TARGETING DIFFERENT ASPECTS OF LEARNING AND MEMORY
Dorner-Ciossek, Cornelia, Delotterie, David, Mathis, Chantal, Cassel, Jean-Christophe, Rosenbrock, Holger, Marti, Anelise
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
Expression of brain derived neurotrophic factor, activity-regulated cytoskeleton protein mRNA, and enhancement of adult hippocampal neurogenesis in rats after sub-chronic and chronic treatment with the triple monoamine re-uptake inhibitor tesofensine
Larsen, Marianne H., Rosenbrock, Holger, Sams-Dodd, Frank, Mikkelsen, Jens D.
Published in European journal of pharmacology (26.01.2007)
Published in European journal of pharmacology (26.01.2007)
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RESTORING LONG-TERM POTENTIATION IMPAIRED BY AMYLOID-BETA OLIGOMERS: COMPARISON OF A BROADLY-SPECIFIC ANTI AMYLOID-BETA NANOBODY AND A MONOMER-SPECIFIC ANTIBODY
Kroker, Katja, Hobson, Scott, Rosenbrock, Holger, Lamla, Thorsten, Vercammen, Jo, Beste, Gerald, Merchiers, Pascal, Dorner-Ciossek, Cornelia, Lenter, Martin
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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