Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing
Prystaz, Katja, Kaiser, Kathrin, Kovtun, Anna, Haffner-Luntzer, Melanie, Fischer, Verena, Rapp, Anna E., Liedert, Astrid, Strauss, Gudrun, Waetzig, Georg H., Rose-John, Stefan, Ignatius, Anita
Published in The American journal of pathology (01.02.2018)
Published in The American journal of pathology (01.02.2018)
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Inhibition of IL‐6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer
Goumas, Freya A., Holmer, Reinhild, Egberts, Jan‐Hendrik, Gontarewicz, Artur, Heneweer, Carola, Geisen, Ulf, Hauser, Charlotte, Mende, Maria‐Margarete, Legler, Karen, Röcken, Christoph, Becker, Thomas, Waetzig, Georg H., Rose‐John, Stefan, Kalthoff, Holger
Published in International journal of cancer (01.09.2015)
Published in International journal of cancer (01.09.2015)
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Natural Glycoforms of Human Interleukin 6 Show Atypical Plasma Clearance
Reif, Andreas, Lam, Kevin, Weidler, Sascha, Lott, Marie, Boos, Irene, Lokau, Juliane, Bretscher, Christian, Mönnich, Manuel, Perkams, Lukas, Schmälzlein, Marina, Graf, Christopher, Fischer, Jan‐Patrick, Lechner, Carolin, Hallstein, Kerstin, Becker, Stefan, Weyand, Michael, Steegborn, Clemens, Schultheiss, Gerhard, Rose‐John, Stefan, Garbers, Christoph, Unverzagt, Carlo
Published in Angewandte Chemie International Edition (07.06.2021)
Published in Angewandte Chemie International Edition (07.06.2021)
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Oncostatin M induces hyperalgesic priming and amplifies signaling of cAMP to ERK by RapGEF2 and PKA
Garza Carbajal, Anibal, Ebersberger, Andrea, Thiel, Alina, Ferrari, Luiz, Acuna, Jeremy, Brosig, Stephanie, Isensee, Joerg, Moeller, Katharina, Siobal, Maike, Rose‐John, Stefan, Levine, Jon, Schaible, Hans‐Georg, Hucho, Tim
Published in Journal of neurochemistry (01.06.2021)
Published in Journal of neurochemistry (01.06.2021)
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Idiopathic multicentric Castleman disease with marrow fibrosis and extramedullary hematopoiesis
Blommers, Marley, Selegean, Sorin, Wood, Richard K., Sarmiento Bustamante, Mateo, Shyamsundar, Saishravan, Wiley, E. Ashley, Comeau, Emilie, Shawwa, Allam A., Rose‐John, Stefan, Fajgenbaum, David C., Chen, Luke Y. C.
Published in European journal of haematology (01.12.2024)
Published in European journal of haematology (01.12.2024)
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ADAM17 selectively activates the IL‐6 trans‐signaling/ERK MAPK axis in KRAS‐addicted lung cancer
Saad, Mohamed I, Alhayyani, Sultan, McLeod, Louise, Yu, Liang, Alanazi, Mohammad, Deswaerte, Virginie, Tang, Ke, Jarde, Thierry, Smith, Julian A, Prodanovic, Zdenka, Tate, Michelle D, Balic, Jesse J, Watkins, D Neil, Cain, Jason E, Bozinovski, Steven, Algar, Elizabeth, Kohmoto, Tomohiro, Ebi, Hiromichi, Ferlin, Walter, Garbers, Christoph, Ruwanpura, Saleela, Sagi, Irit, Rose‐John, Stefan, Jenkins, Brendan J
Published in EMBO molecular medicine (01.04.2019)
Published in EMBO molecular medicine (01.04.2019)
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Semisynthesis of Biologically Active Glycoforms of the Human Cytokine Interleukin 6
Reif, Andreas, Siebenhaar, Sebastian, Tröster, Andrea, Schmälzlein, Marina, Lechner, Carolin, Velisetty, Phanindra, Gottwald, Karen, Pöhner, Claudia, Boos, Irene, Schubert, Volker, Rose-John, Stefan, Unverzagt, Carlo
Published in Angewandte Chemie International Edition (03.11.2014)
Published in Angewandte Chemie International Edition (03.11.2014)
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The shedding protease ADAM17: Physiology and pathophysiology
Zunke, Friederike, Rose-John, Stefan
Published in Biochimica et biophysica acta. Molecular cell research (01.11.2017)
Published in Biochimica et biophysica acta. Molecular cell research (01.11.2017)
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Single‐cell transcriptomics reveals a senescence‐associated IL‐6/CCR6 axis driving radiodermatitis
Paldor, Mor, Levkovitch‐Siany, Orr, Eidelshtein, Dana, Adar, Revital, Enk, Claes D, Marmary, Yitzhak, Elgavish, Sharona, Nevo, Yuval, Benyamini, Hadar, Plaschkes, Inbar, Klein, Shiri, Mali, Alex, Rose‐John, Stefan, Peled, Amnon, Galun, Eithan, Axelrod, Jonathan H
Published in EMBO molecular medicine (08.08.2022)
Published in EMBO molecular medicine (08.08.2022)
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Senescence-associated release of transmembrane proteins involves proteolytic processing by ADAM17 and microvesicle shedding
Effenberger, Timo, von der Heyde, Jan, Bartsch, Kareen, Garbers, Christoph, Schulze-Osthoff, Klaus, Chalaris, Athena, Murphy, Gillian, Rose-John, Stefan, Rabe, Björn
Published in The FASEB journal (01.11.2014)
Published in The FASEB journal (01.11.2014)
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Interleukin 6–dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis
Lanton, Tali, Shriki, Anat, Nechemia‐Arbely, Yael, Abramovitch, Rinat, Levkovitch, Orr, Adar, Revital, Rosenberg, Nofar, Paldor, Mor, Goldenberg, Daniel, Sonnenblick, Amir, Peled, Amnon, Rose‐John, Stefan, Galun, Eithan, Axelrod, Jonathan H.
Published in Hepatology (Baltimore, Md.) (01.05.2017)
Published in Hepatology (Baltimore, Md.) (01.05.2017)
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Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions
Martin, Praxedis, Palmer, Gaby, Vigne, Solenne, Lamacchia, Céline, Rodriguez, Emiliana, Talabot‐Ayer, Dominique, Rose‐John, Stefan, Chalaris, Athena, Gabay, Cem
Published in Journal of leukocyte biology (01.10.2013)
Published in Journal of leukocyte biology (01.10.2013)
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Genetic partitioning of interleukin‐6 signalling in mice dissociates Stat3 from Smad3‐mediated lung fibrosis
O'Donoghue, Robert J. J., Knight, Darryl A., Richards, Carl D., Prêle, Cecilia M., Lau, Hui Ling, Jarnicki, Andrew G., Jones, Jessica, Bozinovski, Steven, Vlahos, Ross, Thiem, Stefan, McKenzie, Brent S., Wang, Bo, Stumbles, Philip, Laurent, Geoffrey J., McAnulty, Robin J., Rose‐John, Stefan, Zhu, Hong Jian, Anderson, Gary P., Ernst, Matthias R., Mutsaers, Steven E.
Published in EMBO molecular medicine (01.09.2012)
Published in EMBO molecular medicine (01.09.2012)
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ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of lethal septic shock
Conrad, Udo, Plagmann, Ingo, Malchow, Sven, Sack, Markus, Floss, Doreen M, Kruglov, Andrei A, Nedospasov, Sergei A, Rose-John, Stefan, Scheller, Jürgen
Published in Plant biotechnology journal (01.01.2011)
Published in Plant biotechnology journal (01.01.2011)
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