Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer
Khasnis, Mukta D, Halkidis, Konstantine, Bhardwaj, Anshul, Root, Michael J
Published in PLoS pathogens (19.12.2016)
Published in PLoS pathogens (19.12.2016)
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Journal Article
Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of HIV-1 Env
Schapiro, Hannah M, Khasnis, Mukta D, Ahn, Koree, Karagiaridi, Alexandra, Hayden, Stephanie, Cilento, Maria E, Root, Michael J
Published in PLoS pathogens (18.05.2022)
Published in PLoS pathogens (18.05.2022)
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Journal Article
Design of a Potent d-Peptide HIV-1 Entry Inhibitor with a Strong Barrier to Resistance
WELCH, Brett D, FRANCIS, J. Nicholas, ROOT, Michael J, KAY, Michael S, REDMAN, Joseph S, PAUL, Suparna, WEINSTOCK, Matthew T, REEVES, Jacqueline D, LIE, Yolanda S, WHITBY, Frank G, ECKERT, Debra M, HILL, Christopher P
Published in Journal of Virology (01.11.2010)
Published in Journal of Virology (01.11.2010)
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Journal Article
Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators
Zhang, Shiyu, Holmes, Andrew P, Dick, Alexej, Rashad, Adel A, Enríquez Rodríguez, Lucía, Canziani, Gabriela A, Root, Michael J, Chaiken, Irwin M
Published in Retrovirology (09.10.2021)
Published in Retrovirology (09.10.2021)
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Journal Article
Interactions of HIV-1 Inhibitory Peptide T20 with the gp41 N-HR Coiled Coil
Champagne, Kelly, Shishido, Akira, Root, Michael J.
Published in The Journal of biological chemistry (06.02.2009)
Published in The Journal of biological chemistry (06.02.2009)
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Journal Article
Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus
Leslie, George J, Wang, Jianbin, Richardson, Max W, Haggarty, Beth S, Hua, Kevin L, Duong, Jennifer, Secreto, Anthony J, Jordon, Andrea P O, Romano, Josephine, Kumar, Kritika E, DeClercq, Joshua J, Gregory, Philip D, June, Carl H, Root, Michael J, Riley, James L, Holmes, Michael C, Hoxie, James A
Published in PLoS pathogens (01.11.2016)
Published in PLoS pathogens (01.11.2016)
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Journal Article
Characterization of resistance to a potent D-peptide HIV entry inhibitor
Smith, Amanda R, Weinstock, Matthew T, Siglin, Amanda E, Whitby, Frank G, Francis, J Nicholas, Hill, Christopher P, Eckert, Debra M, Root, Michael J, Kay, Michael S
Published in Retrovirology (22.10.2019)
Published in Retrovirology (22.10.2019)
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Journal Article
Neutralization of botulinum neurotoxin by a human monoclonal antibody specific for the catalytic light chain
Adekar, Sharad P, Takahashi, Tsuyoshi, Jones, R Mark, Al-Saleem, Fetweh H, Ancharski, Denise M, Root, Michael J, Kapadnis, B P, Simpson, Lance L, Dessain, Scott K
Published in PloS one (20.08.2008)
Published in PloS one (20.08.2008)
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Journal Article
Hybridoma populations enriched for affinity-matured human IgGs yield high-affinity antibodies specific for botulinum neurotoxins
Adekar, Sharad P., Jones, R. Mark, Elias, M.D., Al-Saleem, Fetweh H., Root, Michael J., Simpson, Lance L., Dessain, Scott K.
Published in Journal of immunological methods (20.04.2008)
Published in Journal of immunological methods (20.04.2008)
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Journal Article
Site-Specific Polymer Attachment to HR2 Peptide Fusion Inhibitors against HIV‑1 Decreases Binding Association Rates and Dissociation Rates Rather Than Binding Affinity
Danial, Maarten, Stauffer, Angela N, Wurm, Frederik R, Root, Michael J, Klok, Harm-Anton
Published in Bioconjugate chemistry (15.03.2017)
Published in Bioconjugate chemistry (15.03.2017)
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Journal Article
Protein Design of an HIV-1 Entry Inhibitor
Root, Michael J., Kay, Michael S., Kim, Peter S.
Published in Science (American Association for the Advancement of Science) (02.02.2001)
Published in Science (American Association for the Advancement of Science) (02.02.2001)
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Journal Article