Monomer-on-Monomer (MoM) Mitsunobu Reaction: Facile Purification Utilizing Surface-Initiated Sequestration
Maity, Pradip K, Rolfe, Alan, Samarakoon, Thiwanka B, Faisal, Saqib, Kurtz, Ryan D, Long, Toby R, Schätz, Alexander, Flynn, Daniel L, Grass, Robert N, Stark, Wendelin J, Reiser, Oliver, Hanson, Paul R
Published in Organic letters (07.01.2011)
Published in Organic letters (07.01.2011)
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Journal Article
High-Load, Oligomeric Dichlorotriazine: A Versatile ROMP-Derived Reagent and Scavenger
Rolfe, Alan, Probst, Donald A, Volp, Kelly A, Omar, Iman, Flynn, Daniel L, Hanson, Paul R
Published in Journal of organic chemistry (21.11.2008)
Published in Journal of organic chemistry (21.11.2008)
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Journal Article
Exploring chemical diversity via a modular reaction pairing strategy
Loh, Joanna K, Yoon, Sun Young, Samarakoon, Thiwanka B, Rolfe, Alan, Porubsky, Patrick, Neuenswander, Benjamin, Lushington, Gerald H, Hanson, Paul R
Published in Beilstein journal of organic chemistry (15.08.2012)
Published in Beilstein journal of organic chemistry (15.08.2012)
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Journal Article
Abstract 2467: Heme-CMap: Generation and characterization of ~20K L1000 profiles across 11 hematologic malignant lines
Huang, Chia-Ling, Yang, Andrew, Natoli, Ted, Litichevskiy, Lev, Vaillancourt, Frederic, Rolfe, Alan, Xiao, Yonghong, Subramanian, Aravind, Yu, Lihua
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity
Nguyen, Tuong-Vi, Yao, Shihua, Wang, Yahong, Rolfe, Alan, Selvaraj, Anand, Darman, Rachel, Ke, Jiyuan, Warmuth, Markus, Smith, Peter G., Larsen, Nicholas A., Yu, Lihua, Zhu, Ping, Fekkes, Peter, Vaillancourt, Frédéric H., Bolduc, David M.
Published in The Journal of biological chemistry (08.11.2019)
Published in The Journal of biological chemistry (08.11.2019)
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Journal Article
Domino Heck–Aza‐Michael Reactions: A One‐Pot, Sequential Three‐Component Approach to 1,1‐Dioxido‐1,2‐benzisothiazoline‐3‐acetic Acid
Rolfe, Alan, Young, Kyle, Hanson, Paul R.
Published in European Journal of Organic Chemistry (01.11.2008)
Published in European Journal of Organic Chemistry (01.11.2008)
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Book Review
Journal Article
Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket
Yao, Shihua, Nguyen, Tuong-Vi, Rolfe, Alan, Agrawal, Anant A., Ke, Jiyuan, Peng, Shouyong, Colombo, Federico, Yu, Sean, Bouchard, Patricia, Wu, Jiayi, Huang, Kuan-Chun, Bao, Xingfeng, Omoto, Kiyoyuki, Selvaraj, Anand, Yu, Lihua, Ioannidis, Stephanos, Vaillancourt, Frédéric H., Zhu, Ping, Larsen, Nicholas A., Bolduc, David M.
Published in Cell chemical biology (19.03.2020)
Published in Cell chemical biology (19.03.2020)
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Journal Article
Abstract 2334: Discovery of selective inhibitors of carbamoyl phosphate synthetase I (CPS1) to modulate cancer relevant metabolic pathways
Yao, Shihua, Nguyen, Tuong-Vi, Rolfe, Alan, Agrawal, Anant A., Ke, Jiyuan, Peng, Shouyong, Colombo, Federico, Yu, Sean, Bouchard, Patricia, Wu, Jiayi, Huang, Kuan-Chun, Bao, Xingfeng, Omoto, Kiyoyuki, Selvaraj, Anand, Yu, Lihua, Ioannidis, Stephanos, Vaillancourt, Frédéric H., Zhu, Ping, Larsen, Nicholas A., Bolduc, David M.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Multi-purpose deployer for ITER in-vessel maintenance
Choi, Chang-Hwan, Tesini, Alessandro, Subramanian, Rajendran, Rolfe, Alan, Mills, Simon, Scott, Robin, Froud, Tim, Haist, Bernhard, McCarron, Eddie
Published in Fusion engineering and design (01.10.2015)
Published in Fusion engineering and design (01.10.2015)
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Journal Article
Scaling Out by Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS): Multi-Gram Synthesis of Bromo- and Fluoro-benzofused Sultams Benzthiaoxazepine-1,1-dioxides
Ullah, Farman, Samarakoon, Thiwanka, Rolfe, Alan, Kurtz, Ryan D., Hanson, Paul R., Organ, Michael G.
Published in Chemistry : a European journal (24.09.2010)
Published in Chemistry : a European journal (24.09.2010)
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Journal Article
PPARγ 조절제 및 사용 방법
DRANSFIELD PAUL, OMOTO KIYOYUKI, CARTY MEGAN, COOK ANDREW, LEE HYELEE, IOANNIDIS STEPHANOS, ROLFE ALAN, LIU XIANG, PRAJAPATI SUDEEP
Year of Publication 14.07.2023
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Year of Publication 14.07.2023
Patent
Discovery of 2,6-Dimethylpiperazines as Allosteric Inhibitors of CPS1
Rolfe, Alan, Yao, Shihua, Toung-Vi Nguyen, Omoto, Kiyoyuki, Colombo, Federico, Virrankoski, Milena, Vaillancourt, Frederic H., Yu, Lihua, Cook, Andrew, Reynolds, Dominic, Ioannidis, Stephanos, Zhu, Ping, Larsen, Nicholas A., Bolduc, David M.
Published in ACS medicinal chemistry letters (11.06.2020)
Published in ACS medicinal chemistry letters (11.06.2020)
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Journal Article
Reagent based DOS: A "Click, Click, Cyclize" strategy to probe chemical space
Rolfe, Alan, Lushington, Gerald. H., Hanson, Paul R.
Published in Organic & biomolecular chemistry (01.01.2010)
Published in Organic & biomolecular chemistry (01.01.2010)
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Journal Article
High-Load, Hybrid Si-ROMP Reagents
Rolfe, Alan, Loh, Joanna K, Maity, Pradip K, Hanson, Paul R
Published in Organic letters (07.01.2011)
Published in Organic letters (07.01.2011)
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Journal Article