Structural basis of a shared antibody response to SARS-CoV-2
Yuan, Meng, Liu, Hejun, Wu, Nicholas C, Lee, Chang-Chun D, Zhu, Xueyong, Zhao, Fangzhu, Huang, Deli, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Rogers, Thomas F, Landais, Elise, Sok, Devin, Jardine, Joseph G, Burton, Dennis R, Wilson, Ian A
Published in Science (28.08.2020)
Published in Science (28.08.2020)
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Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Rogers, Thomas F, Zhao, Fangzhu, Huang, Deli, Beutler, Nathan, Burns, Alison, He, Wan-Ting, Limbo, Oliver, Smith, Chloe, Song, Ge, Woehl, Jordan, Yang, Linlin, Abbott, Robert K, Callaghan, Sean, Garcia, Elijah, Hurtado, Jonathan, Parren, Mara, Peng, Linghang, Ramirez, Sydney, Ricketts, James, Ricciardi, Michael J, Rawlings, Stephen A, Wu, Nicholas C, Yuan, Meng, Smith, Davey M, Nemazee, David, Teijaro, John R, Voss, James E, Wilson, Ian A, Andrabi, Raiees, Briney, Bryan, Landais, Elise, Sok, Devin, Jardine, Joseph G, Burton, Dennis R
Published in Science (21.08.2020)
Published in Science (21.08.2020)
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A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection
Zhou, Panpan, Yuan, Meng, Song, Ge, Beutler, Nathan, Shaabani, Namir, Huang, Deli, He, Wan-Ting, Zhu, Xueyong, Callaghan, Sean, Yong, Peter, Anzanello, Fabio, Peng, Linghang, Ricketts, James, Parren, Mara, Garcia, Elijah, Rawlings, Stephen A, Smith, Davey M, Nemazee, David, Teijaro, John R, Rogers, Thomas F, Wilson, Ian A, Burton, Dennis R, Andrabi, Raiees
Published in Science translational medicine (23.03.2022)
Published in Science translational medicine (23.03.2022)
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Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform
Chiuppesi, Flavia, Salazar, Marcela d’Alincourt, Contreras, Heidi, Nguyen, Vu H., Martinez, Joy, Park, Yoonsuh, Nguyen, Jenny, Kha, Mindy, Iniguez, Angelina, Zhou, Qiao, Kaltcheva, Teodora, Levytskyy, Roman, Ebelt, Nancy D., Kang, Tae Hyuk, Wu, Xiwei, Rogers, Thomas F., Manuel, Edwin R., Shostak, Yuriy, Diamond, Don J., Wussow, Felix
Published in Nature communications (30.11.2020)
Published in Nature communications (30.11.2020)
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Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
Garcia, Gustavo, Sharma, Arun, Ramaiah, Arunachalam, Sen, Chandani, Purkayastha, Arunima, Kohn, Donald B., Parcells, Mark S., Beck, Sebastian, Kim, Heeyoung, Bakowski, Malina A., Kirkpatrick, Melanie G., Riva, Laura, Wolff, Karen C., Han, Brandon, Yuen, Constance, Ulmert, David, Purbey, Prabhat K., Scumpia, Philip, Beutler, Nathan, Rogers, Thomas F., Chatterjee, Arnab K., Gabriel, Gülsah, Bartenschlager, Ralf, Gomperts, Brigitte, Svendsen, Clive N., Betz, Ulrich A.K., Damoiseaux, Robert D., Arumugaswami, Vaithilingaraja
Published in Cell reports (Cambridge) (06.04.2021)
Published in Cell reports (Cambridge) (06.04.2021)
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Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19
Tindle, Courtney, Fuller, MacKenzie, Fonseca, Ayden, Taheri, Sahar, Ibeawuchi, Stella-Rita, Beutler, Nathan, Katkar, Gajanan Dattatray, Claire, Amanraj, Castillo, Vanessa, Hernandez, Moises, Russo, Hana, Duran, Jason, Crotty Alexander, Laura E, Tipps, Ann, Lin, Grace, Thistlethwaite, Patricia A, Chattopadhyay, Ranajoy, Rogers, Thomas F, Sahoo, Debashis, Ghosh, Pradipta, Das, Soumita
Published in eLife (13.08.2021)
Published in eLife (13.08.2021)
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Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes
Hurtado, Jonathan, Rogers, Thomas F., Jaffe, David B., Adams, Bruce A., Bangaru, Sandhya, Garcia, Elijah, Capozzola, Tazio, Messmer, Terrence, Sharma, Pragati, Song, Ge, Beutler, Nathan, He, Wanting, Dueker, Katharina, Musharrafieh, Rami, Burbach, Sarah, Truong, Alina, Stubbington, Michael J.T., Burton, Dennis R., Andrabi, Raiees, Ward, Andrew B., McDonnell, Wyatt J., Briney, Bryan
Published in Cell reports (Cambridge) (25.06.2024)
Published in Cell reports (Cambridge) (25.06.2024)
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AI-guided discovery of the invariant host response to viral pandemics
Sahoo, Debashis, Katkar, Gajanan D., Khandelwal, Soni, Behroozikhah, Mahdi, Claire, Amanraj, Castillo, Vanessa, Tindle, Courtney, Fuller, MacKenzie, Taheri, Sahar, Rogers, Thomas F., Beutler, Nathan, Ramirez, Sydney I., Rawlings, Stephen A., Pretorius, Victor, Smith, Davey M., Burton, Dennis R., Alexander, Laura E. Crotty, Duran, Jason, Crotty, Shane, Dan, Jennifer M., Das, Soumita, Ghosh, Pradipta
Published in EBioMedicine (01.06.2021)
Published in EBioMedicine (01.06.2021)
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Response of Extraintestinal Pathogenic Escherichia coli to Human Serum Reveals a Protective Role for Rcs-Regulated Exopolysaccharide Colanic Acid
Miajlovic, Helen, Cooke, Niamh M, Moran, Gary P, Rogers, Thomas R F, Smith, Stephen G
Published in Infection and Immunity (01.01.2014)
Published in Infection and Immunity (01.01.2014)
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Impaired Interferon-γ Responses, Increased Interleukin-17 Expression, and a Tumor Necrosis Factor–α Transcriptional Program in Invasive Aspergillosis
Armstrong-James, Darius P. H., Turnbull, Suzy A., Teo, Ian, Stark, Jaroslav, Rogers, Nicola J., Rogers, Thomas R. F., Bignell, Elaine, Haynes, Ken
Published in The Journal of infectious diseases (15.10.2009)
Published in The Journal of infectious diseases (15.10.2009)
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Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples
Quick, Joshua, Grubaugh, Nathan D, Pullan, Steven T, Claro, Ingra M, Smith, Andrew D, Gangavarapu, Karthik, Oliveira, Glenn, Robles-Sikisaka, Refugio, Rogers, Thomas F, Beutler, Nathan A, Burton, Dennis R, Lewis-Ximenez, Lia Laura, de Jesus, Jaqueline Goes, Giovanetti, Marta, Hill, Sarah C, Black, Allison, Bedford, Trevor, Carroll, Miles W, Nunes, Marcio, Alcantara, Luiz Carlos, Sabino, Ester C, Baylis, Sally A, Faria, Nuno R, Loose, Matthew, Simpson, Jared T, Pybus, Oliver G, Andersen, Kristian G, Loman, Nicholas J
Published in Nature protocols (01.06.2017)
Published in Nature protocols (01.06.2017)
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Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
Zhou, Panpan, Song, Ge, Liu, Hejun, Yuan, Meng, He, Wan-ting, Beutler, Nathan, Zhu, Xueyong, Tse, Longping V., Martinez, David R., Schäfer, Alexandra, Anzanello, Fabio, Yong, Peter, Peng, Linghang, Dueker, Katharina, Musharrafieh, Rami, Callaghan, Sean, Capozzola, Tazio, Limbo, Oliver, Parren, Mara, Garcia, Elijah, Rawlings, Stephen A., Smith, Davey M., Nemazee, David, Jardine, Joseph G., Safonova, Yana, Briney, Bryan, Rogers, Thomas F., Wilson, Ian A., Baric, Ralph S., Gralinski, Lisa E., Burton, Dennis R., Andrabi, Raiees
Published in Immunity (Cambridge, Mass.) (14.03.2023)
Published in Immunity (Cambridge, Mass.) (14.03.2023)
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Drug repurposing screens identify chemical entities for the development of COVID-19 interventions
Bakowski, Malina A., Beutler, Nathan, Wolff, Karen C., Kirkpatrick, Melanie G., Chen, Emily, Nguyen, Tu-Trinh H., Riva, Laura, Shaabani, Namir, Parren, Mara, Ricketts, James, Gupta, Anil K., Pan, Kastin, Kuo, Peiting, Fuller, MacKenzie, Garcia, Elijah, Teijaro, John R., Yang, Linlin, Sahoo, Debashis, Chi, Victor, Huang, Edward, Vargas, Natalia, Roberts, Amanda J., Das, Soumita, Ghosh, Pradipta, Woods, Ashley K., Joseph, Sean B., Hull, Mitchell V., Schultz, Peter G., Burton, Dennis R., Chatterjee, Arnab K., McNamara, Case W., Rogers, Thomas F.
Published in Nature communications (03.06.2021)
Published in Nature communications (03.06.2021)
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Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses
He, Wan-ting, Musharrafieh, Rami, Song, Ge, Dueker, Katharina, Tse, Longping V., Martinez, David R., Schäfer, Alexandra, Callaghan, Sean, Yong, Peter, Beutler, Nathan, Torres, Jonathan L., Volk, Reid M., Zhou, Panpan, Yuan, Meng, Liu, Hejun, Anzanello, Fabio, Capozzola, Tazio, Parren, Mara, Garcia, Elijah, Rawlings, Stephen A., Smith, Davey M., Wilson, Ian A., Safonova, Yana, Ward, Andrew B., Rogers, Thomas F., Baric, Ralph S., Gralinski, Lisa E., Burton, Dennis R., Andrabi, Raiees
Published in Nature immunology (01.06.2022)
Published in Nature immunology (01.06.2022)
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Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern
Cho, Hyeseon, Gonzales-Wartz, Kristina Kay, Huang, Deli, Yuan, Meng, Peterson, Mary, Liang, Janie, Beutler, Nathan, Torres, Jonathan L, Cong, Yu, Postnikova, Elena, Bangaru, Sandhya, Talana, Chloe Adrienna, Shi, Wei, Yang, Eun Sung, Zhang, Yi, Leung, Kwanyee, Wang, Lingshu, Peng, Linghang, Skinner, Jeff, Li, Shanping, Wu, Nicholas C, Liu, Hejun, Dacon, Cherrelle, Moyer, Thomas, Cohen, Melanie, Zhao, Ming, Lee, Frances Eun-Hyung, Weinberg, Rona S, Douagi, Iyadh, Gross, Robin, Schmaljohn, Connie, Pegu, Amarendra, Mascola, John R, Holbrook, Michael, Nemazee, David, Rogers, Thomas F, Ward, Andrew B, Wilson, Ian A, Crompton, Peter D, Tan, Joshua
Published in Science translational medicine (20.10.2021)
Published in Science translational medicine (20.10.2021)
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Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection
Oh, Chang-ki, Nakamura, Tomohiro, Beutler, Nathan, Zhang, Xu, Piña-Crespo, Juan, Talantova, Maria, Ghatak, Swagata, Trudler, Dorit, Carnevale, Lauren N., McKercher, Scott R., Bakowski, Malina A., Diedrich, Jolene K., Roberts, Amanda J., Woods, Ashley K., Chi, Victor, Gupta, Anil K., Rosenfeld, Mia A., Kearns, Fiona L., Casalino, Lorenzo, Shaabani, Namir, Liu, Hejun, Wilson, Ian A., Amaro, Rommie E., Burton, Dennis R., Yates, John R., Becker, Cyrus, Rogers, Thomas F., Chatterjee, Arnab K., Lipton, Stuart A.
Published in Nature chemical biology (01.03.2023)
Published in Nature chemical biology (01.03.2023)
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Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques
Magnani, Diogo M, Rogers, Thomas F, Beutler, Nathan, Ricciardi, Michael J, Bailey, Varian K, Gonzalez-Nieto, Lucas, Briney, Bryan, Sok, Devin, Le, Khoa, Strubel, Alexander, Gutman, Martin J, Pedreño-Lopez, Núria, Grubaugh, Nathan D, Silveira, Cassia G T, Maxwell, Helen S, Domingues, Aline, Martins, Mauricio A, Lee, David E, Okwuazi, Erica E, Jean, Sherrie, Strobert, Elizabeth A, Chahroudi, Ann, Silvestri, Guido, Vanderford, Thomas H, Kallas, Esper G, Desrosiers, Ronald C, Bonaldo, Myrna C, Whitehead, Stephen S, Burton, Dennis R, Watkins, David I
Published in Science translational medicine (04.10.2017)
Published in Science translational medicine (04.10.2017)
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Discovery of CMX990: A Potent SARS-CoV‑2 3CL Protease Inhibitor Bearing a Novel Warhead
Dayan Elshan, N. G. R., Wolff, Karen C., Riva, Laura, Woods, Ashley K., Grabovyi, Gennadii, Wilson, Katy, Pedroarena, James, Ghorai, Sourav, Nazarian, Armen, Weiss, Frank, Liu, Yuyin, Mazumdar, Wrickban, Song, Lirui, Okwor, Neechi, Malvin, Jacqueline, Bakowski, Malina A., Beutler, Nathan, Kirkpatrick, Melanie G., Gebara-Lamb, Amal, Huang, Edward, Nguyen-Tran, Vân T. B., Chi, Victor, Li, Shuangwei, Rogers, Thomas F., McNamara, Case W., Gupta, Anil Kumar, Rahimi, Alireza, Chen, Jian Jeffrey, Joseph, Sean B., Schultz, Peter G., Chatterjee, Arnab K.
Published in Journal of medicinal chemistry (22.02.2024)
Published in Journal of medicinal chemistry (22.02.2024)
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Correction to “Discovery of CMX990: A Potent SARS-CoV‑2 3CL Protease Inhibitor Bearing a Novel Warhead”
Elshan, N. G. R. Dayan, Wolff, Karen C., Riva, Laura, Woods, Ashley K., Grabovyi, Gennadii, Wilson, Katy, Pedroarena, James, Ghorai, Sourav, Nazarian, Armen, Weiss, Frank, Liu, Yuyin, Mazumdar, Wrickban, Song, Lirui, Okwor, Neechi, Malvin, Jacqueline, Liu, Dongdong, Bakowski, Malina A., Beutler, Nathan, Kirkpatrick, Melanie G., Gebara-Lamb, Amal, Huang, Edward, Nguyen-Tran, Vân T. B., Chi, Victor, Li, Shuangwei, Rogers, Thomas F., McNamara, Case W., Gupta, Anil Kumar, Rahimi, Alireza, Chen, Jian Jeffrey, Joseph, Sean B., Schultz, Peter G., Chatterjee, Arnab K.
Published in Journal of medicinal chemistry (27.06.2024)
Published in Journal of medicinal chemistry (27.06.2024)
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