Iron Overload, Oxidative Stress, and Ferroptosis in the Failing Heart and Liver
Mancardi, Daniele, Mezzanotte, Mariarosa, Arrigo, Elisa, Barinotti, Alice, Roetto, Antonella
Published in Antioxidants (24.11.2021)
Published in Antioxidants (24.11.2021)
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Journal Article
Activation of the Hepcidin-Ferroportin1 pathway in the brain and astrocytic–neuronal crosstalk to counteract iron dyshomeostasis during aging
Mezzanotte, Mariarosa, Ammirata, Giorgia, Boido, Marina, Stanga, Serena, Roetto, Antonella
Published in Scientific reports (09.07.2022)
Published in Scientific reports (09.07.2022)
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Journal Article
Post-translational down-regulation of Nrf2 and YAP proteins, by targeting deubiquitinases, reduces growth and chemoresistance in pancreatic cancer cells
Grattarola, Margherita, Cucci, Marie Angèle, Roetto, Antonella, Dianzani, Chiara, Barrera, Giuseppina, Pizzimenti, Stefania
Published in Free radical biology & medicine (01.10.2021)
Published in Free radical biology & medicine (01.10.2021)
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Journal Article
Iron: An Essential Element of Cancer Metabolism
Hsu, Myriam Y, Mina, Erica, Roetto, Antonella, Porporato, Paolo E
Published in Cells (Basel, Switzerland) (03.12.2020)
Published in Cells (Basel, Switzerland) (03.12.2020)
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Journal Article
Crosstalk between Nrf2 and YAP contributes to maintaining the antioxidant potential and chemoresistance in bladder cancer
Ciamporcero, Eric, Daga, Martina, Pizzimenti, Stefania, Roetto, Antonella, Dianzani, Chiara, Compagnone, Alessandra, Palmieri, Antonietta, Ullio, Chiara, Cangemi, Luigi, Pili, Roberto, Barrera, Giuseppina
Published in Free radical biology & medicine (01.02.2018)
Published in Free radical biology & medicine (01.02.2018)
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Journal Article
The Functional Versatility of Transferrin Receptor 2 and Its Therapeutic Value
Roetto, Antonella, Mezzanotte, Mariarosa, Pellegrino, Rosa Maria
Published in Pharmaceuticals (Basel, Switzerland) (23.10.2018)
Published in Pharmaceuticals (Basel, Switzerland) (23.10.2018)
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Journal Article
Wnt5a is a key target for the pro-osteogenic effects of iron chelation on osteoblast progenitors
Baschant, Ulrike, Rauner, Martina, Balaian, Ekaterina, Weidner, Heike, Roetto, Antonella, Platzbecker, Uwe, Hofbauer, Lorenz C
Published in Haematologica (Roma) (01.12.2016)
Published in Haematologica (Roma) (01.12.2016)
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Journal Article
Hepcidin is decreased in TFR2 hemochromatosis
Nemeth, Elizabeta, Roetto, Antonella, Garozzo, Giovanni, Ganz, Tomas, Camaschella, Clara
Published in Blood (15.02.2005)
Published in Blood (15.02.2005)
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Journal Article
Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis
Forejtnikovà, Hana, Vieillevoye, Maud, Zermati, Yael, Lambert, Mireille, Pellegrino, Rosa Maria, Guihard, Soizic, Gaudry, Muriel, Camaschella, Clara, Lacombe, Catherine, Roetto, Antonella, Mayeux, Patrick, Verdier, Frédérique
Published in Blood (09.12.2010)
Published in Blood (09.12.2010)
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Journal Article
Comprehensive analysis of mitochondrial and nuclear DNA variations in patients affected by hemoglobinopathies: A pilot study
Barbanera, Ylenia, Arcioni, Francesco, Lancioni, Hovirag, La Starza, Roberta, Cardinali, Irene, Matteucci, Caterina, Nofrini, Valeria, Roetto, Antonella, Piga, Antonio, Grammatico, Paola, Caniglia, Maurizio, Mecucci, Cristina, Gorello, Paolo
Published in PloS one (22.10.2020)
Published in PloS one (22.10.2020)
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Journal Article
Characterization of human mitochondrial ferritin promoter: identification of transcription factors and evidences of epigenetic control
Guaraldo, Michela, Santambrogio, Paolo, Rovelli, Elisabetta, Di Savino, Augusta, Saglio, Giuseppe, Cittaro, Davide, Roetto, Antonella, Levi, Sonia
Published in Scientific reports (14.09.2016)
Published in Scientific reports (14.09.2016)
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Journal Article
Deferasirox is a powerful NF-κB inhibitor in myelodysplastic cells and in leukemia cell lines acting independently from cell iron deprivation by chelation and reactive oxygen species scavenging
MESSA, Emanuela, CARTURAN, Sonia, ZANONE, Chiara, ROTOLO, Antonia, GRECO, Elisabetta, PELLEGRINO, Rosa M, ALBERTI, Daniele, SAGLIO, Giuseppe, CILLONI, Daniela, MAFFE, Chiara, PAUTASSO, Marisa, BRACCO, Enrico, ROETTO, Antonella, MESSA, Francesca, ARRUGA, Francesca, DEFILIPPI, Ilaria, ROSSO, Valentina
Published in Haematologica (Roma) (01.08.2010)
Published in Haematologica (Roma) (01.08.2010)
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Journal Article
Nrf2 as a Therapeutic Target in the Resistance to Targeted Therapies in Melanoma
Cucci, Marie Angèle, Grattarola, Margherita, Monge, Chiara, Roetto, Antonella, Barrera, Giuseppina, Caputo, Emilia, Dianzani, Chiara, Pizzimenti, Stefania
Published in Antioxidants (20.06.2023)
Published in Antioxidants (20.06.2023)
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Journal Article
The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice
Nai, Antonella, Pellegrino, Rosa M, Rausa, Marco, Pagani, Alessia, Boero, Martina, Silvestri, Laura, Saglio, Giuseppe, Roetto, Antonella, Camaschella, Clara
Published in Haematologica (Roma) (01.06.2014)
Published in Haematologica (Roma) (01.06.2014)
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Journal Article
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
Gasparini, Paolo, Camaschella, Clara, Roetto, Antonella, Calì, Angelita, De Gobbi, Marco, Garozzo, Giovanni, Carella, Massimo, Majorano, Nunzia, Totaro, Angela
Published in Nature genetics (01.05.2000)
Published in Nature genetics (01.05.2000)
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Journal Article
Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation
POLI, Maura, LUSCIETI, Sara, GANDINI, Valentina, MACCARINELLI, Federica, FINAZZI, Dario, SILVESTRI, Laura, ROETTO, Antonella, AROSIO, Paolo
Published in Haematologica (Roma) (01.11.2010)
Published in Haematologica (Roma) (01.11.2010)
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Journal Article
New mutations inactivating transferrin receptor 2 in hemochromatosis type 3
Roetto, Antonella, Totaro, Angela, Piperno, Alberto, Piga, Antonio, Longo, Filomena, Garozzo, Giovanni, Calı̀, Angelita, De Gobbi, Marco, Gasparini, Paolo, Camaschella, Clara
Published in Blood (01.05.2001)
Published in Blood (01.05.2001)
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Journal Article
Natural history of juvenile haemochromatosis
De Gobbi, Marco, Roetto, Antonella, Piperno, Alberto, Mariani, Raffaella, Alberti, Federica, Papanikolaou, George, Politou, Marianna, Lockitch, Gillian, Girelli, Domenico, Fargion, Silvia, Cox, Thimoty M., Gasparini, Paolo, Cazzola, Mario, Camaschella, Clara
Published in British journal of haematology (01.06.2002)
Published in British journal of haematology (01.06.2002)
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Journal Article
A child with hyperferritinemia: case report
Serra, Melania, Longo, Filomena, Roetto, Antonella, Sandri, Alessandro, Piga, Antonio
Published in Italian journal of pediatrics (12.05.2011)
Published in Italian journal of pediatrics (12.05.2011)
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Journal Article