Discovery of novel triazolo[4,3-b]pyridazin-3-yl-quinoline derivatives as PIM inhibitors
Martínez-González, Sonia, Rodríguez-Arístegui, Sonsoles, Gómez de la Oliva, Cristina Ana, Hernández, Ana Isabel, González Cantalapiedra, Esther, Varela, Carmen, García, Ana Belén, Rabal, Obdulia, Oyarzabal, Julen, Bischoff, James R., Klett, Javier, Albarrán, María Isabel, Cebriá, Antonio, Ajenjo, Nuria, García-Serelde, Beatriz, Gómez-Casero, Elena, Cuadrado-Urbano, Manuel, Cebrián, David, Blanco-Aparicio, Carmen, Pastor, Joaquín
Published in European journal of medicinal chemistry (15.04.2019)
Published in European journal of medicinal chemistry (15.04.2019)
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Journal Article
Generation of tricyclic imidazo[1,2-a]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy
Martínez González, Sonia, Rodríguez-Arístegui, Sonsoles, Hernández, Ana Isabel, Varela, Carmen, González Cantalapiedra, Esther, Álvarez, Rosa María, Rodríguez Hergueta, Antonio, Bischoff, James R., Albarrán, María Isabel, Cebriá, Antonio, Cendón, Elena, Cebrián, David, Alfonso, Patricia, Pastor, Joaquín
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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Journal Article
Imidazo[1,2-a]pyrazines as novel PI3K inhibitors
Martínez González, Sonia, Hernández, Ana Isabel, Varela, Carmen, Rodríguez-Arístegui, Sonsoles, Alvarez, Rosa María, García, Ana Belén, Lorenzo, Milagros, Rivero, Virginia, Oyarzabal, Julen, Rabal, Obdulia, Bischoff, James R., Albarrán, Maribel, Cebriá, Antonio, Alfonso, Patricia, Link, Wolfgang, Fominaya, Jesús, Pastor, Joaquín
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Journal Article
Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor
Martínez González, Sonia, Hernández, Ana Isabel, Varela, Carmen, Rodríguez-Arístegui, Sonsoles, Lorenzo, Milagros, Rodríguez, Antonio, Rivero, Virginia, Martín, José Ignacio, Saluste, Carl Gustav, Ramos-Lima, Francisco, Cendón, Elena, Cebrián, David, Aguirre, Enara, Gomez-Casero, Elena, Albarrán, Maribel, Alfonso, Patricia, García-Serelde, Beatriz, Oyarzabal, Julen, Rabal, Obdulia, Mulero, Francisca, Gonzalez-Granda, Teresa, Link, Wolfgang, Fominaya, Jesús, Barbacid, Mariano, Bischoff, James R., Pizcueta, Pilar, Pastor, Joaquín
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
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Journal Article
New use of bis(benzotriazolyl)-1,2-(dialkylamino)ethanes for the synthesis of 2-H-3-dialkylamino imidazo[1,2-a]pyrazine derivatives
Pastor, Joaquín, Rodríguez-Arístegui, Sonsoles, Hernández, Ana Isabel, Varela, Carmen, Salgado, Antonio, Martínez, Sonia
Published in Tetrahedron letters (29.02.2012)
Published in Tetrahedron letters (29.02.2012)
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Journal Article
Versatile synthesis of functionalised dibenzothiophenes via Suzuki coupling and microwave-assisted ring closure
Rodriguez-Aristegui, Sonsoles, Clapham, Kate M., Barrett, Lauren, Cano, Celine, Desage-El Murr, Marine, Griffin, Roger J., Hardcastle, Ian R., Payne, Sara L., Rennison, Tommy, Richardson, Caroline, Golding, Bernard T.
Published in Organic & biomolecular chemistry (07.09.2011)
Published in Organic & biomolecular chemistry (07.09.2011)
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Journal Article
Tricyclic inhibitors of atr
Murga Costa, Matilde, Lopez Contreras, Andrés Joaquín, Varela Busto, Carmen, Blanco Aparicio, Carmen, Renner, Oliver, Cebrián Muñoz, David Alvaro, Nieto Soler, María, Rodríguez Arísteguí, Sonsoles, Pastor Fernández, Joaquín, Fernández-Capetillo Ruiz, Oscar, Toledo Lázaro, Luis Ignacio, Martínez González, Sonia, Rico Ferreira, María Del Rosario
Year of Publication 28.02.2020
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Year of Publication 28.02.2020
Patent
CHEMICAL ENTITIES
OSCAR FERNÁNDEZ-CAPETILLO RUIZ, LUIS IGNACIO TOLEDO LÁZARO, JOAQUÍN PASTOR FERNÁNDEZ, DAVID ALVARO CEBRIÁN MUÑOZ, SONSOLES RODRÍGUEZ ARÍSTEGUÍ, CARMEN VARELA BUSTO, CARMEN BLANCO APARICIO, MATILDE MURGA COSTA, MARÍA DEL ROSARIO RICO FERREIRA, SONIA MARTÍNEZ GONZÁLEZ
Year of Publication 25.05.2018
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Year of Publication 25.05.2018
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CHEMICAL ENTITIES
CEBRIÁN MUÑOZ, DAVID ALVARO, RODRÍGUEZ ARÍSTEGUÍ, SONSOLES, MURGA COSTA, MATILDE, PASTOR FERNÁNDEZ, JOAQUÍN, FERNÁNDEZ-CAPETILLO RUIZ, OSCAR, MARTÍNEZ GONZÁLEZ, SONIA, LOPEZ CONTRERAS, ANDRÉS JOAQUÍN, RICO FERREIRA, MARÍA DEL ROSARIO, NIETO SOLER, MARÍA, BLANCO APARICIO, CARMEN, VARELA BUSTO, CARMEN, TOLEDO LÁZARO, LUIS IGNACIO, RENNER, OLIVER
Year of Publication 31.08.2018
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Year of Publication 31.08.2018
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CHEMICAL ENTITIES
FERNÁNDEZ-CAPETILLO, RUIZ, OSCAR, MARTÍNEZ, GONZÁLEZ, SONIA, CEBRIÁN, MUÑOZ, DAVID, ALVARO, TOLEDO, LÁZARO, LUIS, IGNACIO, VARELA, BUSTO, CARMEN, LOPEZ, CONTRERAS, ANDRÉS, JOAQUÍN, RODRÍGUEZ, ARÍSTEGUÍ, SONSOLES, NIETO, SOLER, MARÍA, PASTOR, FERNÁNDEZ, JOAQUÍN, RICO, FERREIRA, MARÍA DEL ROSARIO, BLANCO, APARICIO, CARMEN, RENNER, OLIVER, MURGA, COSTA, MATILDE
Year of Publication 31.07.2018
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Year of Publication 31.07.2018
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CHEMICAL ENTITIES
Murga Costa, Matilde, Lopez Contreras, Andrés Joaquín, Rico Ferreira, María del Rosario, Pastor Fernández, Joaquin, Varela Busto, Carmen, Blanco Aparicio, Carmen, Renner, Oliver, Cebrián Muñoz, David Alvaro, Nieto Soler, María, Rodríguez Arísteguí, Sonsoles, Fernández-Capetillo Ruiz, Oscar, Toledo Lázaro, Luis Ignacio, Martínez González, Sonia
Year of Publication 29.06.2018
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Year of Publication 29.06.2018
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KEMISKE ENHEDER
MURGA COSTA, Matilde, BLANCO APARICIO, Carmen, PASTOR FERNÁNDEZ, Joaquín, VARELA BUSTO, Carmen, CEBRIÁN MUÑOZ, David Alvaro, TOLEDO LÁZARO, Luis Ignacio, LOPEZ CONTRERAS, Andrés Joaquín, NIETO SOLER, María, RICO FERREIRA, María del Rosario, RENNER, Oliver, RODRÍGUEZ ARÍSTEGUÍ, Sonsoles, FERNÁNDEZ-CAPETILLO RUIZ, Oscar, MARTÍNEZ GONZÁLEZ, Sonia
Year of Publication 22.05.2018
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Year of Publication 22.05.2018
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CHEMICAL ENTITIES
BLANCO APARICIO, Carmen, MURGA COSTA, Matilde, PASTOR FERNÁNDEZ, Joaquín, VARELA BUSTO, Carmen, TOLEDO LÁZARO, Luis Ignacio, CEBRIÁN MUÑOZ, David Alvaro, LOPEZ CONTRERAS, Andrés Joaquín, NIETO SOLER, María, RICO FERREIRA, María del Rosario, RODRÍGUEZ ARÍSTEGUÍ, Sonsoles, RENNER, Oliver, FERNÁNDEZ-CAPETILLO RUIZ, Oscar, MARTÍNEZ GONZÁLEZ, Sonia
Year of Publication 28.02.2018
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Year of Publication 28.02.2018
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ENTIDADES QUÍMICAS
JOAQUÍN PASTOR FERNÁNDEZ, MARÍA NIETO SOLER, SONSOLES RODRÍGUEZ ARÍSTEGUÍ, CARMEN VARELA BUSTO, ANDRÉS JOAQUÍN LOPEZ CONTRERAS, MATILDE MURGA COSTA, DAVID ÁLVARO CEBRÍAN MUÑOZ, MARÍA DEL ROSARIO RICO FERREIRA, SONIA MARTÍNEZ GONZÁLEZ, OSCAR FERNÁNDEZ-CAPETILLO RUIZ, LUIS IGNACIO TOLEDO LÁZARO, OLIVER RENNER, CARMEN BLANCO APARICIO
Year of Publication 05.07.2022
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Year of Publication 05.07.2022
Patent
Chemical entities
Lopez Contreras Andrés Joaquín, Rodríguez Arísteguí Sonsoles, Cebrián Muñoz David Alvaro, Rico Ferreira María del Rosario, Renner Oliver, Pastor Fernández Joaquín, Fernández-Capetillo Ruiz Oscar, Martínez González Sonia, Nieto Soler María, Blanco Aparicio Carmen, Varela Busto Carmen, Murga Costa Matilde, Toledo Lázaro Luis Ignacio
Year of Publication 27.09.2016
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Year of Publication 27.09.2016
Patent
CHEMICAL ENTITIES
LOPEZ CONTRERAS ANDRÉS JOAQUÍN, MURGA COSTA MATILDE, BLANCO APARICIO CARMEN, MARTÍNEZ GONZÁLEZ SONIA, VARELA BUSTO CARMEN, RICO FERREIRA MARÍA DEL ROSARIO, PASTOR FERNÁNDEZ JOAQUÍN, FERNÁNDEZ-CAPETILLO RUIZ OSCAR, CEBRIÁN MUÑOZ DAVID ALVARO, RODRÍGUEZ ARÍSTEGUÍ SONSOLES, NIETO SOLER MARÍA, TOLEDO LÁZARO LUIS IGNACIO, RENNER OLIVER
Year of Publication 28.01.2016
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Year of Publication 28.01.2016
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CHEMICAL ENTITIES
CEBRIÁN MUÑOZ, DAVID ALVARO, RODRÍGUEZ ARÍSTEGUÍ, SONSOLES, MURGA COSTA, MATILDE, PASTOR FERNÁNDEZ, JOAQUÍN, FERNÁNDEZ-CAPETILLO RUIZ, OSCAR, MARTÍNEZ GONZÁLEZ, SONIA, LOPEZ CONTRERAS, ANDRÉS JOAQUÍN, RICO FERREIRA, MARÍA DEL ROSARIO, NIETO SOLER, MARÍA, BLANCO APARICIO, CARMEN, VARELA BUSTO, CARMEN, TOLEDO LÁZARO, LUIS IGNACIO, RENNER, OLIVER
Year of Publication 20.01.2016
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Year of Publication 20.01.2016
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CHEMICAL ENTITIES
CEBRIÁN MUÑOZ, DAVID ALVARO, RODRÍGUEZ ARÍSTEGUÍ, SONSOLES, MURGA COSTA, MATILDE, PASTOR FERNÁNDEZ, JOAQUÍN, FERNÁNDEZ-CAPETILLO RUIZ, OSCAR, MARTÍNEZ GONZÁLEZ, SONIA, LOPEZ CONTRERAS, ANDRÉS JOAQUÍN, RICO FERREIRA, MARÍA DEL ROSARIO, NIETO SOLER, MARÍA, BLANCO APARICIO, CARMEN, VARELA BUSTO, CARMEN, TOLEDO LÁZARO, LUIS IGNACIO, RENNER, OLIVER
Year of Publication 29.10.2015
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Year of Publication 29.10.2015
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CHEMICAL ENTITIES
CEBRIÁN MUÑOZ, DAVID ALVARO, RODRÍGUEZ ARÍSTEGUÍ, SONSOLES, MURGA COSTA, MATILDE, PASTOR FERNÁNDEZ, JOAQUÍN, FERNÁNDEZ-CAPETILLO RUIZ, OSCAR, MARTÍNEZ GONZÁLEZ, SONIA, LOPEZ CONTRERAS, ANDRÉS JOAQUÍN, RICO FERREIRA, MARÍA DEL ROSARIO, NIETO SOLER, MARÍA, BLANCO APARICIO, CARMEN, VARELA BUSTO, CARMEN, TOLEDO LÁZARO, LUIS IGNACIO, RENNER, OLIVER
Year of Publication 18.09.2014
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Year of Publication 18.09.2014
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ΧΗΜΙΚΕΣ ΟΝΤΟΤΗΤΕΣ
BLANCO APARICIO, Carmen, MURGA COSTA, Matilde, PASTOR FERNÁNDEZ, Joaquín, VARELA BUSTO, Carmen, TOLEDO LÁZARO, Luis Ignacio, CEBRIÁN MUÑOZ, David Alvaro, LOPEZ CONTRERAS, Andrés Joaquín, NIETO SOLER, María, RICO FERREIRA, María del Rosario, RODRÍGUEZ ARÍSTEGUÍ, Sonsoles, RENNER, Oliver, FERNÁNDEZ-CAPETILLO RUIZ, Oscar, MARTÍNEZ GONZÁLEZ, Sonia
Year of Publication 11.12.2019
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Year of Publication 11.12.2019
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