Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer
Shah, Khyati N., Bhatt, Roma, Rotow, Julia, Rohrberg, Julia, Olivas, Victor, Wang, Victoria E., Hemmati, Golzar, Martins, Maria M., Maynard, Ashley, Kuhn, Jonathan, Galeas, Jacqueline, Donnella, Hayley J., Kaushik, Swati, Ku, Angel, Dumont, Sophie, Krings, Gregor, Haringsma, Henry J., Robillard, Liliane, Simmons, Andrew D., Harding, Thomas C., McCormick, Frank, Goga, Andrei, Blakely, Collin M., Bivona, Trever G., Bandyopadhyay, Sourav
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
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Alveolar Epithelial Cell Mesenchymal Transition Develops in vivo during Pulmonary Fibrosis and Is Regulated by the Extracellular Matrix
Kim, Kevin K., Kugler, Matthias C., Wolters, Paul J., Robillard, Liliane, Galvez, Michael G., Brumwell, Alexis N., Sheppard, Dean, Chapman, Harold A.
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2006)
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Journal Article
Regulation of α5β1 Integrin Conformation and Function by Urokinase Receptor Binding
Wei, Ying, Czekay, Ralf-Peter, Robillard, Liliane, Kugler, Matthias C., Zhang, Feng, Kim, Kevin K., Xiong, Jian-ping, Humphries, Martin J., Chapman, Harold A.
Published in The Journal of cell biology (31.01.2005)
Published in The Journal of cell biology (31.01.2005)
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Multimodal Microvascular Imaging Reveals that Selective Inhibition of Class I PI3K Is Sufficient to Induce an Antivascular Response
Sampath, Deepak, Oeh, Jason, Wyatt, Shelby K, Cao, Tim C, Koeppen, Hartmut, Eastham-Anderson, Jeffrey, Robillard, Liliane, Ho, Calvin C.K, Ross, Jed, Zhuang, Guanglei, Reslan, Hani Bou, Vitorino, Philip, Barck, Kai H, Ungersma, Sharon E, Vernes, Jean Michel, Caunt, Maresa, Van Bruggen, Nick, Ye, Weilan, Vijapurkar, Ulka, Meng, Yu-Ju Gloria, Ferrara, Napoleone, Friedman, Lori S, Carano, Richard A.D
Published in Neoplasia (New York, N.Y.) (01.07.2013)
Published in Neoplasia (New York, N.Y.) (01.07.2013)
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Differential desensitization of dopamine D2 receptor isoforms by protein kinase C : The importance of receptor phosphorylation and pseudosubstrate sites
MORRIS, Stephen J, ITZHAKI VAN-HAM, Irit, DAIGLE, Mireille, ROBILLARD, Liliane, SAJEDI, Naghmeh, ALBERT, Paul R
Published in European journal of pharmacology (22.12.2007)
Published in European journal of pharmacology (22.12.2007)
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Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma
Kondrashova, Olga, Nguyen, Minh, Shield-Artin, Kristy, Tinker, Anna V, Teng, Nelson N H, Harrell, Maria I, Kuiper, Michael J, Ho, Gwo-Yaw, Barker, Holly, Jasin, Maria, Prakash, Rohit, Kass, Elizabeth M, Sullivan, Meghan R, Brunette, Gregory J, Bernstein, Kara A, Coleman, Robert L, Floquet, Anne, Friedlander, Michael, Kichenadasse, Ganessan, O'Malley, David M, Oza, Amit, Sun, James, Robillard, Liliane, Maloney, Lara, Bowtell, David, Giordano, Heidi, Wakefield, Matthew J, Kaufmann, Scott H, Simmons, Andrew D, Harding, Thomas C, Raponi, Mitch, McNeish, Iain A, Swisher, Elizabeth M, Lin, Kevin K, Scott, Clare L
Published in Cancer discovery (01.09.2017)
Published in Cancer discovery (01.09.2017)
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Fibroblast activation protein targeted radiotherapy induces an immunogenic tumor microenvironment and enhances the efficacy of PD-1 immune checkpoint inhibition
Zboralski, Dirk, Osterkamp, Frank, Christensen, Esben, Bredenbeck, Anne, Schumann, Anne, Hoehne, Aileen, Schneider, Eberhard, Paschke, Matthias, Ungewiss, Jan, Haase, Christian, Robillard, Liliane, Simmons, Andrew D., Harding, Thomas C., Nguyen, Minh
Published in European journal of nuclear medicine and molecular imaging (01.07.2023)
Published in European journal of nuclear medicine and molecular imaging (01.07.2023)
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Abstract 1214: Enhancement of anti-PD-1 antitumor efficacy in syngeneic preclinical models by the angiogenesis inhibitor lucitanib
Dusek, Rachel L., Robillard, Liliane, Harding, Thomas C., Simmons, Andrew D., Nguyen, Minh
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 3026: Evaluation of brain pharmacokinetics (PK) and tumor growth inhibition of PARP inhibitors in mouse xenograft models using semi-mechanistic PK/pharmacodynamic (PD) modeling
Liao, Michelle, Jin, Feng, Nguyen, Minh, Robillard, Liliane, Simmons, Andrew D., Harding, Thomas C., Xiao, Jim J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 1716: The PARP inhibitor rucaparib activates the STING pathway and enhances antitumor responses of immune checkpoint inhibitors in BRCA deficient syngeneic models
Nguyen, Minh, Robillard, Liliane, Lin, Kevin K., Harding, Thomas C., Simmons, Andrew D.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Efficacy and immune modulation of the tumor microenvironment with the combination of the PARP inhibitor rucaparib and CD122-biased agonist NKTR-214
Simmons, Andrew, Robillard, Liliane, Nguyen, Minh, Harding, Thomas C., Charych, Deborah H.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Abstract 3888: Intracranial evaluation of the in vivo pharmacokinetics, brain distribution, and efficacy of rucaparib in BRCA -mutant, triple-negative breast cancer
Nguyen, Minh, Robillard, Liliane, Harding, Thomas C., Xiao, Jim J., Simmons, Andrew D., Kristeleit, Hartmut, Liao, Michelle (Mingxiang)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 2202: The combination of a mouse ortholog of ALKS 4230, a selective agonist of the intermediate affinity IL-2 receptor, and the angiogenesis inhibitor lucitanib enhances antitumor activity
Lopes, Jared E., Dusek, Rachel L., Robillard, Liliane, Nguyen, Minh, Roth, Bruce, Vought, Bryan, Liberzon, Arthur, Winquist, Raymond J., Losey, Heather C.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 2835: Fibroblast activation protein (FAP)-targeted radiotherapy increases tumor CD8+ T cell infiltration and enhances response to PD-1 immune checkpoint blockade
Zboralski, Dirk, Höhne, Aileen, Christensen, Esben, Paschke, Matthias, Robillard, Liliane, Simmons, Andrew D., Osterkamp, Frank, Harding, Thomas C., Nguyen, Minh
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract C199: PI3K/AKT/mTOR inhibitors enhance the anti-tumor activity of the FGFR, VEGFR and PDGFR inhibitor lucitanib in FGF-dependent breast cancer models
Nguyen, Minh, Robillard, Liliane, Simmons, Andrew D., Haringsma, Henry J., Harding, Thomas C.
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Abstract 3650: Preclinical evaluation of the PARP inhibitor rucaparib in combination with PD-1 and PD-L1 inhibition in a syngeneic BRCA1 mutant ovarian cancer model
Robillard, Liliane, Nguyen, Minh, Loehr, Andrea, Orsulic, Sandra, Kristeleit, Rebecca S., Lin, Kevin, Raponi, Mitch, Harding, Thomas C., Simmons, Andrew D.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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