Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2
Navaneetham, Duraiswamy, Jin, Lei, Pandey, Pramod, Strickler, James E., Babine, Robert E., Abdel-Meguid, Sherin S., Walsh, Peter N.
Published in The Journal of biological chemistry (28.10.2005)
Published in The Journal of biological chemistry (28.10.2005)
Get full text
Journal Article
Structurally similar estradiol analogs uniquely alter the regulation of intracellular signaling pathways
Yarger, James G, Babine, Robert E, Bittner, Michael, Shanle, Erin, Xu, Wei, Hershberger, Pamela, Nye, Steven H
Published in Journal of molecular endocrinology (01.02.2013)
Published in Journal of molecular endocrinology (01.02.2013)
Get full text
Journal Article
Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants
Lin, Jian, Deng, Hongfeng, Jin, Lei, Pandey, Pramod, Quinn, Jesse, Cantin, Susan, Rynkiewicz, Michael J, Gorga, Joan C, Bibbins, Frank, Celatka, Cassandra A, Nagafuji, Pamela, Bannister, Thomas D, Meyers, Harold V, Babine, Robert E, Hayward, Neil J, Weaver, David, Benjamin, Howard, Stassen, Frans, Abdel-Meguid, Sherin S, Strickler, James E
Published in Journal of medicinal chemistry (28.12.2006)
Published in Journal of medicinal chemistry (28.12.2006)
Get full text
Journal Article
Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an α-ketothiazole arginine
Deng, Hongfeng, Bannister, Thomas D., Jin, Lei, Babine, Robert E., Quinn, Jesse, Nagafuji, Pamela, Celatka, Cassandra A., Lin, Jian, Lazarova, Tsvetelina I., Rynkiewicz, Michael J., Bibbins, Frank, Pandey, Pramod, Gorga, Joan, Meyers, Harold V., Abdel-Meguid, Sherin S., Strickler, James E.
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
Get full text
Journal Article
The three-dimensional structure of the ZAP-70 kinase domain in complex with staurosporine: implications for the design of selective inhibitors
Jin, Lei, Pluskey, Scott, Petrella, Eugene C, Cantin, Susan M, Gorga, Joan C, Rynkiewicz, Michael J, Pandey, Pramod, Strickler, James E, Babine, Robert E, Weaver, David T, Seidl, Katherine J
Published in The Journal of biological chemistry (08.10.2004)
Published in The Journal of biological chemistry (08.10.2004)
Get full text
Journal Article
Conversion of human-selective PPARα agonists to human/mouse dual agonists: a molecular modeling analysis
Wang, Minmin, Winneroski, Leonard L., Ardecky, Robert J., Babine, Robert E., Brooks, Dawn A., Etgen, Garret J., Hutchison, Darrell R., Kauffman, Raymond F., Kunkel, Aaron, Mais, Dale E., Montrose-Rafizadeh, Chahrzad, Ogilvie, Kathleen M., Oldham, Brian A., Peters, Mary K., Rito, Christopher J., Rungta, Deepa K., Tripp, Allie E., Wilson, Sarah B., Xu, Yanping, Zink, Richard W., McCarthy, James R.
Published in Bioorganic & medicinal chemistry letters (20.12.2004)
Published in Bioorganic & medicinal chemistry letters (20.12.2004)
Get full text
Journal Article
Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors
Pandey, Pramod, Babine, Robert E., Weaver, David T., Jin, Lei, Abdel-Meguid, Sherin S., Strickler, James E.
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2005)
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2005)
Get full text
Journal Article
Revision of assignment of structure to the pyrrolodiazepinone antitumor antibiotic sibiromycin
Parker, Kathlyn A, Babine, Robert E
Published in Journal of the American Chemical Society (01.12.1982)
Published in Journal of the American Chemical Society (01.12.1982)
Get full text
Journal Article
Abstract 1721: A steroid-based drug that binds estrogen receptor beta can inhibit cancer cell proliferation by blocking chromosome replication
Weitman, Steven D., Bittner, Michael, Hershberger, Pamela, Babine, Robert E., Nye, Steven, Yarger, James
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Get full text
Journal Article
Synthesis and biological evaluation of a series of HIV-1 protease inhibitors
Trova, Michael P., Babine, Robert E., Byrn, Randal A., Casscles, Wellington T., Hastings, Richard C., Hsu, Grace C., Jirousek, Michael R., Johnson, Bernard D., Kerwar, Suresh S., Schow, Steven R., Wissner, Allan, Zhang, Nan, Wick, Michael M.
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
Published in Bioorganic & medicinal chemistry letters (01.08.1993)
Get full text
Journal Article
CARM1 INHIBITORS AND USES THEREOF
Babine, Robert E, Shapiro, Gideon, Chesworth, Richard, Moradei, Oscar Miguel, Jin, Lei
Year of Publication 28.12.2023
Get full text
Year of Publication 28.12.2023
Patent
Carm1 inhibitors and uses thereof
Babine, Robert E, Shapiro, Gideon, Chesworth, Richard, Moradei, Oscar Miguel, Jin, Lei
Year of Publication 05.12.2023
Get full text
Year of Publication 05.12.2023
Patent
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies
Dragovich, Peter S, Webber, Stephen E, Babine, Robert E, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Lee, Caroline A, Reich, Siegfried H, Prins, Thomas J, Marakovits, Joseph T, Littlefield, Ethel S, Zhou, Ru, Tikhe, Jayashree, Ford, Clifford E, Wallace, Michael B, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Binford, Susan L, Harr, James E. V, DeLisle, Dorothy M, Worland, Stephen T
Published in Journal of medicinal chemistry (16.07.1998)
Published in Journal of medicinal chemistry (16.07.1998)
Get full text
Journal Article
CARM1 INHIBITORS AND USES THEREOF
Babine, Robert E, Shapiro, Gideon, Chesworth, Richard, Moradei, Oscar Miguel, Jin, Lei
Year of Publication 07.09.2023
Get full text
Year of Publication 07.09.2023
Patent
CARM1 INHIBITORS AND USES THEREOF
BABINE, ROBERT E, SHAPIRO, GIDEON, JIN, LEI, CHESWORTH, RICHARD, MORADEL, OSCAR MIGUEL
Year of Publication 29.08.2023
Get full text
Year of Publication 29.08.2023
Patent
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies
Dragovich, Peter S, Webber, Stephen E, Babine, Robert E, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Reich, Siegfried H, Marakovits, Joseph T, Prins, Thomas J, Zhou, Ru, Tikhe, Jayashree, Littlefield, Ethel S, Bleckman, Ted M, Wallace, Michael B, Little, Thomas L, Ford, Clifford E, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Binford, Susan L, DeLisle, Dorothy M, Worland, Stephen T
Published in Journal of medicinal chemistry (16.07.1998)
Published in Journal of medicinal chemistry (16.07.1998)
Get full text
Journal Article
CARM1 INHIBITORS AND USES THEREOF
Babine, Robert E, Shapiro, Gideon, Chesworth, Richard, Moradei, Oscar Miguel, Jin, Lei
Year of Publication 27.05.2021
Get full text
Year of Publication 27.05.2021
Patent
Conversion of human-selective PPARalpha agonists to human/mouse dual agonists: a molecular modeling analysis
Wang, Minmin, Winneroski, Leonard L, Ardecky, Robert J, Babine, Robert E, Brooks, Dawn A, Etgen, Garret J, Hutchison, Darrell R, Kauffman, Raymond F, Kunkel, Aaron, Mais, Dale E, Montrose-Rafizadeh, Chahrzad, Ogilvie, Kathleen M, Oldham, Brian A, Peters, Mary K, Rito, Christopher J, Rungta, Deepa K, Tripp, Allie E, Wilson, Sarah B, Xu, Yanping, Zink, Richard W, McCarthy, James R
Published in Bioorganic & medicinal chemistry letters (20.12.2004)
Get full text
Published in Bioorganic & medicinal chemistry letters (20.12.2004)
Journal Article