COBRA™: a highly potent conditionally active T cell engager engineered for the treatment of solid tumors
Panchal, Anand, Seto, Pui, Wall, Russell, Hillier, Brian J, Zhu, Ying, Krakow, Jessica, Datt, Aakash, Pongo, Elizabeth, Bagheri, Andisheh, Chen, Tseng-Hui T, Degenhardt, Jeremiah D, Culp, Patricia A, Dettling, Danielle E, Vinogradova, Maia V, May, Chad, DuBridge, Robert B
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Journal Article
CRISPR/Cas9 disruption of EpCAM Exon 2 results in cell-surface expression of a truncated protein targeted by an EpCAM specific T cell engager
Bagheri, Andisheh, Culp, Patricia A., DuBridge, Robert B., Chen, Tseng-hui Timothy
Published in Biochemistry and biophysics reports (01.03.2022)
Published in Biochemistry and biophysics reports (01.03.2022)
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Journal Article
Regression of EGFR positive established solid tumors in mice with the conditionally active T cell engager TAK-186
Dettling, Danielle E, Kwok, Eilene, Quach, Lucy, Datt, Aakash, Degenhardt, Jeremiah D, Panchal, Anand, Seto, Pui, Krakow, Jessica L, Wall, Russell, Hillier, Brian J, Zhu, Ying, Vinogradova, Maia, DuBridge, Robert B, May, Chad
Published in Journal for immunotherapy of cancer (01.06.2022)
Published in Journal for immunotherapy of cancer (01.06.2022)
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Journal Article
Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing
Forsyth, Charles M., Juan, Veronica, Akamatsu, Yoshiko, DuBridge, Robert B., Doan, Minhtam, Ivanov, Alexander V., Ma, Zhiyuan, Polakoff, Dixie, Razo, Jennifer, Wilson, Keith, Powers, David B.
Published in mAbs (01.07.2013)
Published in mAbs (01.07.2013)
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Journal Article
A function blocking anti-mouse integrin α5β1 antibody inhibits angiogenesis and impedes tumor growth in vivo
Bhaskar, Vinay, Zhang, Dong, Fox, Melvin, Seto, Pui, Wong, Melanie HL, Wales, Pauline E, Powers, David, Chao, Debra T, DuBridge, Robert B, Ramakrishnan, Vanitha
Published in Journal of translational medicine (27.11.2007)
Published in Journal of translational medicine (27.11.2007)
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Journal Article
Volociximab, a chimeric integrin alpha5beta1 antibody, inhibits the growth of VX2 tumors in rabbits
Bhaskar, Vinay, Fox, Melvin, Breinberg, Danna, Wong, Melanie H-L, Wales, Pauline E., Rhodes, Susan, DuBridge, Robert B., Ramakrishnan, Vanitha
Published in Investigational new drugs (01.02.2008)
Published in Investigational new drugs (01.02.2008)
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Journal Article
The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions
Harding, Fiona A., Stickler, Marcia M., Razo, Jennifer, DuBridge, Robert
Published in mAbs (01.05.2010)
Published in mAbs (01.05.2010)
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Journal Article
TriTACs, a Novel Class of T-Cell-Engaging Protein Constructs Designed for the Treatment of Solid Tumors
Austin, Richard J, Lemon, Bryan D, Aaron, Wade H, Barath, Manasi, Culp, Patricia A, DuBridge, Robert B, Evnin, Luke B, Jones, Adrie, Panchal, Anand, Patnaik, Purbasa, Ramakrishnan, Vanitha, Rocha, Sony S, Seto, Pui, Sexton, Kenneth, Strobel, Kathryn L, Wall, Russell, Yu, Stephen, Yu, Timothy Z, Law, Che-Leung, Baeuerle, Patrick A, Wesche, Holger
Published in Molecular cancer therapeutics (01.01.2021)
Published in Molecular cancer therapeutics (01.01.2021)
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Journal Article
Affinity and cross-reactivity engineering of CTLA4-Ig to modulate T cell costimulation
Xu, Zhenghai, Juan, Veronica, Ivanov, Alexander, Ma, Zhiyuan, Polakoff, Dixie, Powers, David B, Dubridge, Robert B, Wilson, Keith, Akamatsu, Yoshiko
Published in The Journal of immunology (1950) (01.11.2012)
Published in The Journal of immunology (1950) (01.11.2012)
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Journal Article
Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays
Brenner, Sydney, Johnson, Maria, Bridgham, John, Golda, George, Lloyd, David H, Johnson, Davida, Luo, Shujun, McCurdy, Sarah, Foy, Michael, Ewan, Mark, Roth, Rithy, George, Dave, Eletr, Sam, Albrecht, Glenn, Vermaas, Eric, Williams, Steven R, Moon, Keith, Burcham, Timothy, Pallas, Michael, DuBridge, Robert B, Kirchner, James, Fearon, Karen, Mao, Jen-i, Corcoran, Kevin
Published in Nature biotechnology (01.06.2000)
Published in Nature biotechnology (01.06.2000)
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Journal Article
INDUCIBLE BINDING PROTEINS AND METHODS OF USE THEREOF
HOLGER WESCHE, LUKE EVNIN, ROBERT B DUBRIDGE, PATRICK BAEUERLE, MAIA VINOGRADOVA, ANAND PANCHAL, JEANMARIE GUENOT
Year of Publication 05.09.2023
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Year of Publication 05.09.2023
Patent
In vitro Cloning of Complex Mixtures of DNA on Microbeads: Physical Separation of Differentially Expressed cDNAs
Brenner, Sydney, Williams, Steven R., Vermaas, Eric H., Storck, Thorsten, Moon, Keith, McCollum, Christie, Jen-I Mao, Luo, Shujun, Kirchner, James J., Eletr, Sam, DuBridge, Robert B., Burcham, Timothy, Albrecht, Glenn
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2000)
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Journal Article
E-selectin up-regulation allows for targeted drug delivery in prostate cancer
BHASKAR, Vinay, LAW, Debbie A, PONG, Melody, POWERS, Rick, SENTER, Peter, STOCKETT, David, SUTHERLAND, Robert L, VON FREEDEN-JEFFRY, Ursula, WILLHITE, Dorian, MURRAY, Richard, AFAR, Daniel E. H, RAMAKRISHNAN, Vanitha, IBSEN, Eric, BREINBERG, Danna, CASS, Kellie M, DUBRIDGE, Robert B, EVANGELISTA, Ferdinand, HENSHALL, Susan M, HEVEZI, Peter, MILLER, Jennifer C
Published in Cancer research (Chicago, Ill.) (01.10.2003)
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Published in Cancer research (Chicago, Ill.) (01.10.2003)
Journal Article
Increased Thrombin Responsiveness in Platelets from Mice Lacking Glycoprotein V
Ramakrishnan, Vanitha, Reeves, Peter S., DeGuzman, Francis, Deshpande, Usha, Ministri-Madrid, Kathleen, DuBridge, Robert B., Phillips, David R.
Published in Proceedings of the National Academy of Sciences - PNAS (09.11.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (09.11.1999)
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Journal Article
Abstract 557: COBRA: A novel conditionally active bispecific antibody that regresses established solid tumors in mice
Dettling, Danielle, Kwok, Eilene, Quach, Lucy, Datt, Aakash, Degenhardt, Jeremiah D., Vinogradova, Maia, Panchal, Anand, Seto, Pui, Krakow, Jessica L., Wall, Russell, Hillier, Brian J., Zhu, Ying, DuBridge, Robert B., May, Chad
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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