Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo
Derby, Nina, Lal, Manjari, Aravantinou, Meropi, Kizima, Larisa, Barnable, Patrick, Rodriguez, Aixa, Lai, Manshun, Wesenberg, Asa, Ugaonkar, Shweta, Levendosky, Keith, Mizenina, Olga, Kleinbeck, Kyle, Lifson, Jeffrey D, Peet, M Melissa, Lloyd, Zachary, Benson, Michael, Heneine, Walid, O'Keefe, Barry R, Robbiani, Melissa, Martinelli, Elena, Grasperge, Brooke, Blanchard, James, Gettie, Agegnehu, Teleshova, Natalia, Fernández-Romero, José A, Zydowsky, Thomas M
Published in Nature communications (24.09.2018)
Published in Nature communications (24.09.2018)
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Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus
Levendosky, Keith, Mizenina, Olga, Martinelli, Elena, Jean-Pierre, Ninochka, Kizima, Larisa, Rodriguez, Aixa, Kleinbeck, Kyle, Bonnaire, Thierry, Robbiani, Melissa, Zydowsky, Thomas M, O'Keefe, Barry R, Fernández-Romero, José A
Published in Antimicrobial agents and chemotherapy (01.12.2015)
Published in Antimicrobial agents and chemotherapy (01.12.2015)
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Sex hormones selectively impact the endocervical mucosal microenvironment: implications for HIV transmission
Goode, Diana, Aravantinou, Meropi, Jarl, Sebastian, Truong, Rosaline, Derby, Nina, Guerra-Perez, Natalia, Kenney, Jessica, Blanchard, James, Gettie, Agegnehu, Robbiani, Melissa, Martinelli, Elena
Published in PloS one (15.05.2014)
Published in PloS one (15.05.2014)
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Conformation-Dependent Recognition of HIV gp120 by Designed Ankyrin Repeat Proteins Provides Access to Novel HIV Entry Inhibitors
Mann, Axel, Friedrich, Nikolas, Krarup, Anders, Weber, Jacqueline, Stiegeler, Emanuel, Dreier, Birgit, Pugach, Pavel, Robbiani, Melissa, Riedel, Tina, Moehle, Kerstin, Robinson, John A, Rusert, Peter, Plückthun, Andreas, Trkola, Alexandra
Published in Journal of Virology (01.05.2013)
Published in Journal of Virology (01.05.2013)
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A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV
Kizima, Larisa, Rodríguez, Aixa, Kenney, Jessica, Derby, Nina, Mizenina, Olga, Menon, Radhika, Seidor, Samantha, Zhang, Shimin, Levendosky, Keith, Jean-Pierre, Ninochka, Pugach, Pavel, Villegas, Guillermo, Ford, Brian E, Gettie, Agegnehu, Blanchard, James, Piatak, Jr, Michael, Lifson, Jeffrey D, Paglini, Gabriela, Teleshova, Natalia, Zydowsky, Thomas M, Robbiani, Melissa, Fernández-Romero, José A
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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PolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In Vivo
Aravantinou, Meropi, Frank, Ines, Hallor, Magnus, Singer, Rachel, Tharinger, Hugo, Kenney, Jessica, Gettie, Agegnehu, Grasperge, Brooke, Blanchard, James, Salazar, Andres, Piatak, Jr, Michael, Lifson, Jeffrey D, Robbiani, Melissa, Derby, Nina
Published in PloS one (07.09.2016)
Published in PloS one (07.09.2016)
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Zinc Acetate/Carrageenan Gels Exhibit Potent Activity In Vivo against High-Dose Herpes Simplex Virus 2 Vaginal and Rectal Challenge
Fernández-Romero, José A, Abraham, Ciby J, Rodriguez, Aixa, Kizima, Larisa, Jean-Pierre, Ninochka, Menon, Radhika, Begay, Othell, Seidor, Samantha, Ford, Brian E, Gil, Pedro I, Peters, Jennifer, Katz, David, Robbiani, Melissa, Zydowsky, Thomas M
Published in Antimicrobial Agents and Chemotherapy (2012)
Published in Antimicrobial Agents and Chemotherapy (2012)
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An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques
Kenney, Jessica, Aravantinou, Meropi, Singer, Rachel, Hsu, Mayla, Rodriguez, Aixa, Kizima, Larisa, Abraham, Ciby J, Menon, Radhika, Seidor, Samantha, Chudolij, Anne, Gettie, Agegnehu, Blanchard, James, Lifson, Jeffrey D, Piatak, Jr, Michael, Fernández-Romero, Jose A, Zydowsky, Thomas M, Robbiani, Melissa
Published in PloS one (05.01.2011)
Published in PloS one (05.01.2011)
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Rectal HSV-2 Infection May Increase Rectal SIV Acquisition Even in the Context of SIVΔnef Vaccination
Guerra-Pérez, Natalia, Aravantinou, Meropi, Veglia, Filippo, Goode, Diana, Truong, Rosaline, Derby, Nina, Blanchard, James, Grasperge, Brooke, Gettie, Agegnehu, Robbiani, Melissa, Martinelli, Elena
Published in PloS one (17.02.2016)
Published in PloS one (17.02.2016)
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A Modified Zinc Acetate Gel, a Potential Nonantiretroviral Microbicide, Is Safe and Effective against Simian-Human Immunodeficiency Virus and Herpes Simplex Virus 2 Infection In Vivo
KENNEY, Jessica, RODRIGUEZ, Aixa, BLANCHARD, James, PIATAK, Michael, LIFSON, Jeffrey D, PAGLINI, Gabriela, ZYDOWSKY, Thomas M, ROBBIANI, Melissa, FERNANDEZ ROMERO, José A, KIZIMA, Larisa, SEIDOR, Samantha, MENON, Radhika, JEAN-PIERRE, Ninochka, PUGACH, Pavel, LEVENDOSKY, Keith, DERBY, Nina, GETTIE, Agegnehu
Published in Antimicrobial Agents and Chemotherapy (01.08.2013)
Published in Antimicrobial Agents and Chemotherapy (01.08.2013)
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A Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex Vivo
Villegas, Guillermo, Calenda, Giulia, Ugaonkar, Shweta, Zhang, Shimin, Kizima, Larisa, Mizenina, Olga, Gettie, Agegnehu, Blanchard, James, Cooney, Michael L, Robbiani, Melissa, Fernández-Romero, José A, Zydowsky, Thomas M, Teleshova, Natalia
Published in PloS one (18.07.2016)
Published in PloS one (18.07.2016)
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A macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacy
Crostarosa, Federica, Aravantinou, Meropi, Akpogheneta, Onome J, Jasny, Edith, Shaw, Andrew, Kenney, Jessica, Piatak, Michael, Lifson, Jeffrey D, Teitelbaum, Aaron, Hu, Lieyu, Chudolij, Anne, Zydowsky, Thomas M, Blanchard, James, Gettie, Agegnehu, Robbiani, Melissa
Published in PloS one (30.11.2009)
Published in PloS one (30.11.2009)
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Double-Stranded RNA Analog Poly(I:C) Inhibits Human Immunodeficiency Virus Amplification in Dendritic Cells via Type I Interferon-Mediated Activation of APOBEC3G
TRAPP, Susanna, DERBY, Nina R, SINGER, Rachel, SHAW, Andrew, WILLIAMS, Vennansha G, TURVILLE, Stuart G, BESS, Julian W, LIFSON, Jeffrey D, ROBBIANI, Melissa
Published in Journal of Virology (15.01.2009)
Published in Journal of Virology (15.01.2009)
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CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristics
Schweizer, Andreas, Rusert, Peter, Berlinger, Livia, Ruprecht, Claudia R, Mann, Axel, Corthésy, Stéphanie, Turville, Stuart G, Aravantinou, Meropi, Fischer, Marek, Robbiani, Melissa, Amstutz, Patrick, Trkola, Alexandra
Published in PLoS pathogens (01.07.2008)
Published in PLoS pathogens (01.07.2008)
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Journal Article
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
Turville, Stuart G, Aravantinou, Meropi, Miller, Todd, Kenney, Jessica, Teitelbaum, Aaron, Hu, Lieyu, Chudolij, Anne, Zydowsky, Tom M, Piatak, Jr, Michael, Bess, Jr, Julian W, Lifson, Jeffrey D, Blanchard, James, Gettie, Agegnehu, Robbiani, Melissa
Published in PloS one (08.09.2008)
Published in PloS one (08.09.2008)
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Journal Article
Exposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaques
Hsu, Mayla, Keele, Brandon F, Aravantinou, Meropi, Krawczyk, Noa, Seidor, Samantha, Abraham, Ciby J, Zhang, Shimin, Rodriguez, Aixa, Kizima, Larisa, Derby, Nina, Jean-Pierre, Ninochka, Mizenina, Olga, Gettie, Agegnehu, Grasperge, Brooke, Blanchard, James, Piatak, Jr, Michael J, Lifson, Jeffrey D, Fernández-Romero, José A, Zydowsky, Thomas M, Robbiani, Melissa
Published in PloS one (27.02.2014)
Published in PloS one (27.02.2014)
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A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants
Barnable, Patrick, Calenda, Giulia, Ouattara, Louise, Gettie, Agegnehu, Blanchard, James, Jean-Pierre, Ninochka, Kizima, Larisa, Rodríguez, Aixa, Abraham, Ciby, Menon, Radhika, Seidor, Samantha, Cooney, Michael L, Roberts, Kevin D, Sperling, Rhoda, Piatak, Jr, Michael, Lifson, Jeffrey D, Fernandez-Romero, Jose A, Zydowsky, Thomas M, Robbiani, Melissa, Teleshova, Natalia
Published in PloS one (26.09.2014)
Published in PloS one (26.09.2014)
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HSV-2-driven increase in the expression of α4β7 correlates with increased susceptibility to vaginal SHIV(SF162P3) infection
Goode, Diana, Truong, Rosaline, Villegas, Guillermo, Calenda, Giulia, Guerra-Perez, Natalia, Piatak, Michael, Lifson, Jeffrey D, Blanchard, James, Gettie, Agegnehu, Robbiani, Melissa, Martinelli, Elena
Published in PLoS pathogens (01.12.2014)
Published in PLoS pathogens (01.12.2014)
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A tonsillar PolyICLC/AT-2 SIV therapeutic vaccine maintains low viremia following antiretroviral therapy cessation
Vagenas, Panagiotis, Aravantinou, Meropi, Williams, Vennansha G, Jasny, Edith, Piatak, Jr, Michael, Lifson, Jeffrey D, Salazar, Andres M, Blanchard, James L, Gettie, Agegnehu, Robbiani, Melissa
Published in PloS one (21.09.2010)
Published in PloS one (21.09.2010)
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