Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease
Khare, Shilpi, Roach, Steven L, Barnes, S Whitney, Hoepfner, Dominic, Walker, John R, Chatterjee, Arnab K, Neitz, R Jeffrey, Arkin, Michelle R, McNamara, Case W, Ballard, Jaime, Lai, Yin, Fu, Yue, Molteni, Valentina, Yeh, Vince, McKerrow, James H, Glynne, Richard J, Supek, Frantisek
Published in PLoS pathogens (01.07.2015)
Published in PLoS pathogens (01.07.2015)
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Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines
Roach, Steven L., Higuchi, Robert I., Adams, Mark E., Liu, Yan, Karanewsky, Donald S., Marschke, Keith B., Mais, Dale E., Miner, Jeffrey N., Zhi, Lin
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Synthesis and Characterization of Nonsteroidal Glucocorticoid Receptor Modulators for Multiple Myeloma
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Published in Journal of medicinal chemistry (20.09.2007)
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Published in Journal of organic chemistry (19.09.1997)
Published in Journal of organic chemistry (19.09.1997)
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Lead identification to clinical candidate selection: drugs for Chagas disease
Neitz, R Jeffrey, Chen, Steven, Supek, Frantisek, Yeh, Vince, Kellar, Danielle, Gut, Jiri, Bryant, Clifford, Gallardo-Godoy, Alejandra, Molteni, Valentina, Roach, Steven L, Khare, Shilpi, Stinson, Monique, Chatterjee, Arnab K, Robertson, Stephanie, Renslo, Adam R, Arkin, Michelle, Glynne, Richard, McKerrow, James, Siqueira-Neto, Jair L
Published in Journal of biomolecular screening (01.01.2015)
Published in Journal of biomolecular screening (01.01.2015)
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Tetrahydroquinoline glucocorticoid receptor agonists: Discovery of a 3-hydroxyl for improving receptor selectivity
Roach, Steven L., Higuchi, Robert I., Hudson, Andrew R., Adams, Mark E., Syka, Peter M., Mais, Dale E., Miner, Jeffrey N., Marschke, Keith B., Zhi, Lin
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Discovery of orally available tetrahydroquinoline-based glucocorticoid receptor agonists
Hudson, Andrew R., Higuchi, Robert I., Roach, Steven L., Adams, Mark E., Vassar, Angela, Syka, Peter M., Mais, Dale E., Miner, Jeffrey N., Marschke, Keith B., Zhi, Lin
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced PEPCK activation
Hudson, Andrew R., Higuchi, Robert I., Roach, Steven L., Valdez, Lino J., Adams, Mark E., Vassar, Angie, Rungta, Deepa, Syka, Peter M., Mais, Dale E., Marschke, Keith B., Zhi, Lin
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Tetrahydroquinolin-3-yl carbamate glucocorticoid receptor agonists with reduced PEPCK activation
Roach, Steven L., Higuchi, Robert I., Hudson, Andrew R., Vassar, Angie, Grant, Virginia H.S., Lamer, Ryan, Hooper, Charlene, Rungta, Deepa, Syka, Peter M., Mais, Dale E., Marschke, Keith B., Zhi, Lin
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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5 (Z) -Benzylidene -1,2 -dihydro -9 -hydroxy -10 -methoxy -2,2, 4 -trimethyl -5H-1 -aza -6 -oxa -chrysenes as non-steroidal glucocorticoid receptor modulators
ARDECKY, Robert J, HUDSON, Andrew R, LOPEZ, Francisco J, MARSCHKE, Keith B, MINER, Jeffrey N, KARANEWSKY, Donald S, NEGRO-VILAR, Andrés, LIN ZHI, PHILLIPS, Dean P, TYHONAS, John S, DECKHUT, Charlotte, LAU, Thomas L, YONGKAI LI, MARTINBOROUGH, Esther A, ROACH, Steven L, HIGUCHI, Robert I
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
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Zeolite-Mediated Cyclization of an Epoxide-Containing Polyene
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Published in Journal of organic chemistry (27.12.1996)
Published in Journal of organic chemistry (27.12.1996)
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HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES
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Year of Publication 02.04.2013
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Year of Publication 02.04.2013
Patent
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease: e1005058
Khare, Shilpi, Roach, Steven L, Barnes, S Whitney, Hoepfner, Dominic, Walker, John R, Chatterjee, Arnab K, Neitz, R Jeffrey, Arkin, Michelle R, McNamara, Case W, Ballard, Jaime, Lai, Yin, Fu, Yue, Molteni, Valentina, Yeh, Vince, McKerrow, James H, Glynne, Richard J, Supek, Frantisek
Published in PLoS pathogens (01.07.2015)
Published in PLoS pathogens (01.07.2015)
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Discovery of Non-Peptidyl Small-Molecule Human GCSF Receptor Agonists for the Potential Treatment of Neutropenia
Marschke, Keith, Rungta, Deepa, Slavin, Daniela A, Sanders, Jennifer, Roach, Steven L, Pickens, Jason C, Shen, Yixing, van Oeveren, Arjan, Hong, Mei Hua, Sun, Hong, Bissonnette, Reid P., Syka, Peter M, Zhi, Lin
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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NON-Peptidyl Small Molecule EPO Receptor Agonists Are Potent Pathway Selective Inducers of Erythropoiesis
Bissonnette, Reid P., Rungta, Deepa, Hudson, Andrew R, Roach, Steven L, Hong, Mei Hua, Sun, Hong, Hu, Junlian, Ward, James N, Luo, Wen, Sanders, Jen E, Syka, Peter M, Slavin, Daniela A, Zhi, Lin, Marschke, Keith B
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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5( Z)-Benzylidene-1,2-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5 H-1-aza-6-oxa-chrysenes as non-steroidal glucocorticoid receptor modulators
Ardecky, Robert J., Hudson, Andrew R., Phillips, Dean P., Tyhonas, John S., Deckhut, Charlotte, Lau, Thomas L., Li, Yongkai, Martinborough, Esther A., Roach, Steven L., Higuchi, Robert I., Lopez, Francisco J., Marschke, Keith B., Miner, Jeffrey N., Karanewsky, Donald S., Negro-Vilar, Andrés, Zhi, Lin
Published in Bioorganic & medicinal chemistry letters (2007)
Published in Bioorganic & medicinal chemistry letters (2007)
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Methods and compositions associated with the granulocyte colony-stimulating factor receptor
Pedram, Bijan, Marschke, Keith, Pickens, Jason C, Valdez, Lino J, Shen, Yixing, Hudson, Andrew R, Grant, Virginia H, Roach, Steven L, van Oeveren, Cornelis Arjan, Zhi, Lin
Year of Publication 16.08.2022
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Year of Publication 16.08.2022
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