Glycogen and its metabolism: some new developments and old themes
Roach, Peter J, Depaoli-Roach, Anna A, Hurley, Thomas D, Tagliabracci, Vincent S
Published in Biochemical journal (01.02.2012)
Published in Biochemical journal (01.02.2012)
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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase
Tang, Buyun, Frasinyuk, Mykhaylo S, Chikwana, Vimbai M, Mahalingan, Krishna K, Morgan, Cynthia A, Segvich, Dyann M, Bondarenko, Svitlana P, Mrug, Galyna P, Wyrebek, Przemyslaw, Watt, David S, DePaoli-Roach, Anna A, Roach, Peter J, Hurley, Thomas D
Published in Journal of medicinal chemistry (09.04.2020)
Published in Journal of medicinal chemistry (09.04.2020)
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PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease
Turnbull, Julie, DePaoli-Roach, Anna A, Zhao, Xiaochu, Cortez, Miguel A, Pencea, Nela, Tiberia, Erica, Piliguian, Mark, Roach, Peter J, Wang, Peixiang, Ackerley, Cameron A, Minassian, Berge A
Published in PLoS genetics (01.04.2011)
Published in PLoS genetics (01.04.2011)
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Impaired malin expression and interaction with partner proteins in Lafora disease
Skurat, Alexander V., Segvich, Dyann M., Contreras, Christopher J., Hu, Yueh-Chiang, Hurley, Thomas D., DePaoli-Roach, Anna A., Roach, Peter J.
Published in The Journal of biological chemistry (01.05.2024)
Published in The Journal of biological chemistry (01.05.2024)
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Brain glycogen serves as a critical glucosamine cache required for protein glycosylation
Sun, Ramon C., Young, Lyndsay E.A., Bruntz, Ronald C., Markussen, Kia H., Zhou, Zhengqiu, Conroy, Lindsey R., Hawkinson, Tara R., Clarke, Harrison A., Stanback, Alexandra E., Macedo, Jessica K.A., Emanuelle, Shane, Brewer, M. Kathryn, Rondon, Alberto L., Mestas, Annette, Sanders, William C., Mahalingan, Krishna K., Tang, Buyun, Chikwana, Vimbai M., Segvich, Dyann M., Contreras, Christopher J., Allenger, Elizabeth J., Brainson, Christine F., Johnson, Lance A., Taylor, Richard E., Armstrong, Dustin D., Shaffer, Robert, Waechter, Charles J., Vander Kooi, Craig W., DePaoli-Roach, Anna A., Roach, Peter J., Hurley, Thomas D., Drake, Richard R., Gentry, Matthew S.
Published in Cell metabolism (06.07.2021)
Published in Cell metabolism (06.07.2021)
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Phosphate Incorporation during Glycogen Synthesis and Lafora Disease
Tagliabracci, Vincent S., Heiss, Christian, Karthik, Chandra, Contreras, Christopher J., Glushka, John, Ishihara, Mayumi, Azadi, Parastoo, Hurley, Thomas D., DePaoli-Roach, Anna A., Roach, Peter J.
Published in Cell metabolism (02.03.2011)
Published in Cell metabolism (02.03.2011)
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Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry
Young, Lyndsay E.A., Brizzee, Corey O., Macedo, Jessica K.A., Murphy, Robert D., Contreras, Christopher J., DePaoli-Roach, Anna A., Roach, Peter J., Gentry, Matthew S., Sun, Ramon C.
Published in Carbohydrate polymers (15.02.2020)
Published in Carbohydrate polymers (15.02.2020)
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The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex
Fastman, Nathan M., Liu, Yuxi, Ramanan, Vyas, Merritt, Hanne, Ambing, Eileen, DePaoli-Roach, Anna A., Roach, Peter J., Hurley, Thomas D., Mellem, Kevin T., Ullman, Julie C., Green, Eric, Morgans, David, Tzitzilonis, Christos
Published in Cell reports (Cambridge) (05.07.2022)
Published in Cell reports (Cambridge) (05.07.2022)
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Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin
DePaoli-Roach, Anna A., Tagliabracci, Vincent S., Segvich, Dyann M., Meyer, Catalina M., Irimia, Jose M., Roach, Peter J.
Published in The Journal of biological chemistry (13.08.2010)
Published in The Journal of biological chemistry (13.08.2010)
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Clinical effectiveness of drop-in mental health services at paediatric hospitals: A non-randomised multi-site study for children and young people and their families - study protocol
Roach, Anna, Bennett, Sophie, Heyman, Isobel, Coughtrey, Anna, Stokes, Isabella, Ndoci, Xhorxhina, Balakrishnan, Sonia, Astle, Nicki, Drinkwater, Jessie, Evans, Rebecca, Frederick, Una, Groszmann, Michael, Jones, Steve, McDonnell, Katie, Mobley, Amanda, Murray, Abbie, O'Sullivan, Helena, Ormrod, Sarah, Prendegast, Theodore, Rajalingam, Usha, Webster, Emily, Webster, Rebecca, Vinton, Gareth, Shafran, Roz
Published in PloS one (09.05.2024)
Published in PloS one (09.05.2024)
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Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease
Tagliabracci, Vincent S., Girard, Jean Marie, Segvich, Dyann, Meyer, Catalina, Turnbull, Julie, Zhao, Xiaochu, Minassian, Berge A., DePaoli-Roach, Anna A., Roach, Peter J.
Published in The Journal of biological chemistry (05.12.2008)
Published in The Journal of biological chemistry (05.12.2008)
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Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism
Jiang, Sixin, Heller, Brigitte, Tagliabracci, Vincent S., Zhai, Lanmin, Irimia, Jose M., DePaoli-Roach, Anna A., Wells, Clark D., Skurat, Alexander V., Roach, Peter J.
Published in The Journal of biological chemistry (05.11.2010)
Published in The Journal of biological chemistry (05.11.2010)
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Novel method for detection of glycogen in cells
Skurat, Alexander V, Segvich, Dyann M, DePaoli-Roach, Anna A, Roach, Peter J
Published in Glycobiology (Oxford) (01.05.2017)
Published in Glycobiology (Oxford) (01.05.2017)
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Structural Basis for Regulation of Protein Phosphatase 1 by Inhibitor-2
Hurley, Thomas D., Yang, Jie, Zhang, Lili, Goodwin, Kristie D., Zou, Qin, Cortese, Marc, Dunker, A. Keith, DePaoli-Roach, Anna A.
Published in The Journal of biological chemistry (28.09.2007)
Published in The Journal of biological chemistry (28.09.2007)
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Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo
Tagliabracci, Vincent S, Turnbull, Julie, Wang, Wei, Girard, Jean-Marie, Zhao, Xiaochu, Skurat, Alexander V, Delgado-Escueta, Antonio V, Minassian, Berge A, DePaoli-Roach, Anna A, Roach, Peter J
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2007)
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Glycogen Phosphomonoester Distribution in Mouse Models of the Progressive Myoclonic Epilepsy, Lafora Disease
DePaoli-Roach, Anna A., Contreras, Christopher J., Segvich, Dyann M., Heiss, Christian, Ishihara, Mayumi, Azadi, Parastoo, Roach, Peter J.
Published in The Journal of biological chemistry (09.01.2015)
Published in The Journal of biological chemistry (09.01.2015)
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Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders
Ullman, Julie C, Mellem, Kevin T, Xi, Yannan, Ramanan, Vyas, Merritt, Hanne, Choy, Rebeca, Gujral, Tarunmeet, Young, Lyndsay E A, Blake, Kerrigan, Tep, Samnang, Homburger, Julian R, O'Regan, Adam, Ganesh, Sandya, Wong, Perryn, Satterfield, Terrence F, Lin, Baiwei, Situ, Eva, Yu, Cecile, Espanol, Bryan, Sarwaikar, Richa, Fastman, Nathan, Tzitzilonis, Christos, Lee, Patrick, Reiton, Daniel, Morton, Vivian, Santiago, Pam, Won, Walter, Powers, Hannah, Cummings, Beryl B, Hoek, Maarten, Graham, Robert R, Chandriani, Sanjay J, Bainer, Russell, DePaoli-Roach, Anna A, Roach, Peter J, Hurley, Thomas D, Sun, Ramon C, Gentry, Matthew S, Sinz, Christopher, Dick, Ryan A, Noonberg, Sarah B, Beattie, David T, Morgans, Jr, David J, Green, Eric M
Published in Science translational medicine (17.01.2024)
Published in Science translational medicine (17.01.2024)
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