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A novel piwi-interacting RNA associates with type 2–high asthma phenotypes
Li, Jiang, Hong, Xiaoning, Jiang, Mingye, Kho, Alvin T., Tiwari, Anshul, Wang, Alberta L., Chase, Robert P., Celedón, Juan C., Weiss, Scott T., McGeachie, Michael J., Tantisira, Kelan G.
Published in Journal of allergy and clinical immunology (01.03.2024)
Published in Journal of allergy and clinical immunology (01.03.2024)
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RNA interference is essential to modulating the pathogenesis of mosquito-borne viruses in the yellow fever mosquito Aedes aegypti
Samuel, Glady Hazitha, Pohlenz, Tyler, Dong, Yuemei, Coskun, Nese, Adelman, Zach N., Dimopoulos, George, Myles, Kevin M.
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2023)
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Clinical Proof of Concept for a Novel Hepatocyte-Targeting GalNAc-siRNA Conjugate
Zimmermann, Tracy S., Karsten, Verena, Chan, Amy, Chiesa, Joseph, Boyce, Malcolm, Bettencourt, Brian R., Hutabarat, Renta, Nochur, Saraswathy, Vaishnaw, Akshay, Gollob, Jared
Published in Molecular therapy (04.01.2017)
Published in Molecular therapy (04.01.2017)
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Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses
Hristova, Milena, Habibovic, Aida, Veith, Carmen, Janssen-Heininger, Yvonne M.W., Dixon, Anne E., Geiszt, Miklos, van der Vliet, Albert
Published in Journal of allergy and clinical immunology (01.05.2016)
Published in Journal of allergy and clinical immunology (01.05.2016)
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Oncogenic role of PDK4 in human colon cancer cells
Leclerc, D, Pham, D N T, Lévesque, N, Truongcao, M, Foulkes, W D, Sapienza, C, Rozen, R
Published in British journal of cancer (28.03.2017)
Published in British journal of cancer (28.03.2017)
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Central role of c-Src in NOX5- mediated redox signalling in vascular smooth muscle cells in human hypertension
Camargo, Livia L, Montezano, Augusto C, Hussain, Misbah, Wang, Yu, Zou, Zhiguo, Rios, Francisco J, Neves, Karla B, Alves-Lopes, Rheure, Awan, Fazli R, Guzik, Tomasz J, Jensen, Thomas, Hartley, Richard C, Touyz, Rhian M
Published in Cardiovascular research (25.03.2022)
Published in Cardiovascular research (25.03.2022)
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Heterochromatin-dependent transcription links the PRC2 complex to small RNA-mediated DNA elimination
Solberg, Therese, Wang, Chundi, Matsubara, Ryuma, Wen, Zhiwei, Nowacki, Mariusz
Published in EMBO reports (10.01.2025)
Published in EMBO reports (10.01.2025)
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A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma
Brugarolas, James, Obara, Gregory, Beckermann, Kathryn E., Rini, Brian, Lam, Elaine T., Hamilton, James, Schluep, Thomas, Yi, Min, Wong, So, Mao, Zhongping Lily, Gamelin, Erick, Tannir, Nizar M.
Published in Clinical cancer research (03.06.2024)
Published in Clinical cancer research (03.06.2024)
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15-Lipoxygenase 1 in nasal polyps promotes CCL26/eotaxin 3 expression through extracellular signal-regulated kinase activation
Li, Zhipeng, Zeng, Ming, Deng, Yanhan, Zhao, Jinming, Zhou, Xiuxia, Trudeau, John B., Goldschmidt, Ezequiel, Moore, John A., Chu, Hongwei, Zhang, Weitian, Yin, Shankai, Liu, Zheng, Di, Y. Peter, Lee, Stella E., Wenzel, Sally E.
Published in Journal of allergy and clinical immunology (01.11.2019)
Published in Journal of allergy and clinical immunology (01.11.2019)
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The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1
Herrero-Mendez, Angel, Almeida, Angeles, Fernández, Emilio, Maestre, Carolina, Moncada, Salvador, Bolaños, Juan P.
Published in Nature cell biology (01.06.2009)
Published in Nature cell biology (01.06.2009)
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Identification of novel piRNAs in bladder cancer
Chu, Haiyan, Hui, Gaoyun, Yuan, Lin, Shi, Danni, Wang, Yubang, Du, Mulong, Zhong, Dongyan, Ma, Lan, Tong, Na, Qin, Chao, Yin, Changjun, Zhang, Zhengdong, Wang, Meilin
Published in Cancer letters (28.01.2015)
Published in Cancer letters (28.01.2015)
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Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle
Austin, Philip J., Tsitsiou, Eleni, Boardman, Charlotte, Jones, Simon W., Lindsay, Mark A., Adcock, Ian M., Chung, Kian Fan, Perry, Mark M.
Published in Journal of allergy and clinical immunology (01.03.2017)
Published in Journal of allergy and clinical immunology (01.03.2017)
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HIF2 Inactivation and Tumor Suppression with a Tumor-Directed RNA-Silencing Drug in Mice and Humans
Ma, Yuanqing, Joyce, Allison, Brandenburg, Olivia, Saatchi, Faeze, Stevens, Christina, Toffessi Tcheuyap, Vanina, Christie, Alana, Do, Quyen N., Fatunde, Oluwatomilade, Macchiaroli, Alyssa, Wong, So C., Woolford, Layton, Yousuf, Qurratulain, Miyata, Jeffrey, Carrillo, Deyssy, Onabolu, Oreoluwa, McKenzie, Tiffani, Mishra, Akhilesh, Hardy, Tanner, He, Wei, Li, Daniel, Ivanishev, Alexander, Zhang, Qing, Pedrosa, Ivan, Kapur, Payal, Schluep, Thomas, Kanner, Steven B., Hamilton, James, Brugarolas, James
Published in Clinical cancer research (15.12.2022)
Published in Clinical cancer research (15.12.2022)
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randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus
DeVincenzo, John, Lambkin-Williams, Robert, Wilkinson, Tom, Cehelsky, Jeffrey, Nochur, Sara, Walsh, Edward, Meyers, Rachel, Gollob, Jared, Vaishnaw, Akshay
Published in Proceedings of the National Academy of Sciences - PNAS (11.05.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (11.05.2010)
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Inhibition of S-Adenosylhomocysteine Hydrolase Induces Endothelial Dysfunction via Epigenetic Regulation of p66shc-Mediated Oxidative Stress Pathway
Xiao, Yunjun, Xia, Junjie, Cheng, Jinquan, Huang, Haiyan, Zhou, Yani, Yang, Xifei, Su, Xuefen, Ke, Yuebin, Ling, Wenhua
Published in Circulation (New York, N.Y.) (07.05.2019)
Published in Circulation (New York, N.Y.) (07.05.2019)
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Effect of modification of siRNA molecules delivered with aminopropylsilanol nanoparticles on suppression of A/H5N1 virus in cell culture
Repkova, Marina, Mazurkov, Oleg, Filippova, Ekaterina, Protsenko, Maria, Mazurkova, Natalia, Meschaninova, Maria, Levina, Asya, Zarytova, Valentina
Published in Biochimica et biophysica acta. General subjects (01.12.2024)
Published in Biochimica et biophysica acta. General subjects (01.12.2024)
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SLN124, a GalNAc conjugated 19‐mer siRNA targeting tmprss6, reduces plasma iron and increases hepcidin levels of healthy volunteers
Porter, John B., Scrimgeour, Alison, Martinez, Alberto, James, Leo, Aleku, Manuela, Wilson, Rosamund, Muckenthaler, Martina, Boyce, Malcolm, Wilkes, Denise, Schaeper, Ute, Campion, Giles V.
Published in American journal of hematology (01.09.2023)
Published in American journal of hematology (01.09.2023)
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