Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines
Dwyer, Connor J, Knochelmann, Hannah M, Smith, Aubrey S, Wyatt, Megan M, Rangel Rivera, Guillermo O, Arhontoulis, Dimitrios C, Bartee, Eric, Li, Zihai, Rubinstein, Mark P, Paulos, Chrystal M
Published in Frontiers in immunology (20.02.2019)
Published in Frontiers in immunology (20.02.2019)
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Journal Article
Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy
Rangel Rivera, Guillermo O, Knochelmann, Hannah M, Dwyer, Connor J, Smith, Aubrey S, Wyatt, Megan M, Rivera-Reyes, Amalia M, Thaxton, Jessica E, Paulos, Chrystal M
Published in Frontiers in immunology (18.03.2021)
Published in Frontiers in immunology (18.03.2021)
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Journal Article
Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells
Dwyer, Connor J., Arhontoulis, Dimitrios C., Rangel Rivera, Guillermo O, Knochelmann, Hannah M., Smith, Aubrey S., Wyatt, Megan M., Rubinstein, Mark P., Atkinson, Carl, Thaxton, Jessica E., Neskey, David M., Paulos, Chrystal M.
Published in European journal of immunology (01.09.2020)
Published in European journal of immunology (01.09.2020)
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Journal Article
Progressively Enhancing Stemness of Adoptively Transferred T Cells with PI3Kδ Blockade Improves Metabolism and Antitumor Immunity
Rangel Rivera, Guillermo O., Dwyer, Connor J., Knochelmann, Hannah M., Smith, Aubrey S., Aksoy, Bülent Arman, Cole, Anna C., Wyatt, Megan M., Kumaresan, Soundharya, Thaxton, Jessica E., Lesinski, Gregory B., Paulos, Chrystal M.
Published in Cancer research (Chicago, Ill.) (02.01.2024)
Published in Cancer research (Chicago, Ill.) (02.01.2024)
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Journal Article
Sex Differences in Using Systemic Inflammatory Markers to Prognosticate Patients with Head and Neck Squamous Cell Carcinoma
Lin, Ching Ying, Kwon, Hyunwoo, Rangel Rivera, Guillermo O, Li, Xue, Chung, Dongjun, Li, Zihai
Published in Cancer epidemiology, biomarkers & prevention (01.10.2018)
Published in Cancer epidemiology, biomarkers & prevention (01.10.2018)
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Journal Article
Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma
Grohar, Patrick J., Kim, Suntae, Rangel Rivera, Guillermo O., Sen, Nirmalya, Haddock, Sara, Harlow, Matt L., Maloney, Nichole K., Zhu, Jack, O’Neill, Maura, Jones, Tamara L., Huppi, Konrad, Grandin, Magdalena, Gehlhaus, Kristen, Klumpp-Thomas, Carleen A., Buehler, Eugen, Helman, Lee J., Martin, Scott E., Caplen, Natasha J.
Published in Cell reports (Cambridge) (26.01.2016)
Published in Cell reports (Cambridge) (26.01.2016)
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Journal Article
IL6 Fuels Durable Memory for Th17 Cell-Mediated Responses to Tumors
Knochelmann, Hannah M, Dwyer, Connor J, Smith, Aubrey S, Bowers, Jacob S, Wyatt, Megan M, Nelson, Michelle H, Rangel Rivera, Guillermo O, Horton, Joshua D, Krieg, Carsten, Armeson, Kent, Lesinski, Gregory B, Rubinstein, Mark P, Li, Zihai, Paulos, Chrystal M
Published in Cancer research (Chicago, Ill.) (15.09.2020)
Published in Cancer research (Chicago, Ill.) (15.09.2020)
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Journal Article
Augmenting TCR signal strength and ICOS costimulation results in metabolically fit and therapeutically potent human CAR Th17 cells
Wyatt, Megan M., Huff, Logan W., Nelson, Michelle H., Neal, Lillian R., Medvec, Andrew R., Rangel Rivera, Guillermo O., Smith, Aubrey S., Rivera Reyes, Amalia M., Knochelmann, Hannah M., Riley, James L., Lesinski, Gregory B., Paulos, Chrystal M.
Published in Molecular therapy (05.07.2023)
Published in Molecular therapy (05.07.2023)
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Journal Article
B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity
Smith, Aubrey S, Knochelmann, Hannah M, Wyatt, Megan M, Rangel Rivera, Guillermo O, Rivera-Reyes, Amalia M, Dwyer, Connor J, Ware, Michael B, Cole, Anna C, Neskey, David M, Rubinstein, Mark P, Liu, Bei, Thaxton, Jessica E, Bartee, Eric, Paulos, Chrystal M
Published in Journal for immunotherapy of cancer (01.01.2022)
Published in Journal for immunotherapy of cancer (01.01.2022)
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Journal Article
Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies
Knochelmann, Hannah M, Rivera-Reyes, Amalia M, Wyatt, Megan M, Smith, Aubrey S, Chamness, Reilley, Dwyer, Connor J, Bobian, Michael, Rangel Rivera, Guillermo O, Horton, Joshuva D, Lilly, Michael, Romeo, Martin J, Timmers, Cynthia D, Rubinstein, Mark P, Neskey, David M, Paulos, Chrystal M
Published in Oncoimmunology (01.01.2021)
Published in Oncoimmunology (01.01.2021)
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Journal Article
Distinct host preconditioning regimens differentially impact the antitumor potency of adoptively transferred Th17 cells
Wittling, Megen C, Knochelmann, Hannah M, Wyatt, Megan M, Rangel Rivera, Guillermo O, Cole, Anna C, Lesinski, Gregory B, Paulos, Chrystal M
Published in Journal for immunotherapy of cancer (30.06.2024)
Published in Journal for immunotherapy of cancer (30.06.2024)
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Journal Article
9 BRAF mutations are associated with T-helper cell infiltration and polarization in melanoma
Ware, Michael, Pavuluri, Bhavana, Smith, Aubrey, Wyatt, Megan, RIvera, Guillermo Rangel, Cole, Anna, Paulos, Chrystal
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
223 Potent inhibition of PI3Kδ promotes enhanced T cell stemness and mitochondrial fitness
RIvera, Guillermo Rangel, Dwyer, Connor, Knochelmann, Hannah, Smith, Aubrey, Cole, Anna, Wyatt, Megan, Ware, Brandon, Paulos, Chrystal
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Abstract 2008: Ewing sarcoma cells harboring a translocation that retains EWSR1 exon 8 require HNRNPH1 to express the in-frame oncogenic fusion transcript EWS-FLI1
Kim, Suntae, Olivero, Christiane, Rangel Rivera, Guillermo O., Sen, Nirmalya, Haddock, Sara, Huppi, Konrad, Helman, Lee J., Grohar, Patrick J., Caplen, Natasha J.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
159 Adoptively transferred CD8+ T cells that target neoantigen persist and regress melanomas to a greater extent than those that target self/tumor-antigen
Reyes, Amalia Rivera, Wyatt, Megan, Dwyer, Connor, Knochelmann, Hannah, Smith, Aubrey, Rivera, Guillermo Rangel, Paulos, Chrystal
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
158 Inhibition of PI3Kδ improves tumor specific T cell immunity and metabolic fitness
Rivera, Guillermo Rangel, RIvera, Guillermo Rangel, Dwyer, Connor, Arhontoulis, Dimitrios, Knochelmann, Hannah, Smith, Aubrey, Wyatt, Megan, Reyes, Amalia Rivera, Paulos, Chrystal
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
708 Novel ways to exploit IL-21 to augment adoptive T cell transfer therapy against tumors
Cole, Anna, RIvera, Guillermo Rangel, Smith, Aubrey, Wyatt, Megan, Ware, Brandon, Knochelmann, Hannah, Paulos, Chrystal
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
513 CD26 enzymatic activity modulates efficient migration of adoptively transferred T cells to solid tumors
Wyatt, Megan, Bailey, Stefanie, Nelson, Michelle, Knochelmann, Hannah, Smith, Aubrey, RIvera, Guillermo Rangel, Reyes, Amalia Rivera, Paulos, Chrystal
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
119 IL-6 is critical for memory responses elicited by Th17 cells to tumors
Knochelmann, Hannah, Dwyer, Connor, Smith, Aubrey, Wyatt, Megan, RIvera, Guillermo Rangel, Lesinski, Gregory, Li, Zihai, Rubinstein, Mark, Paulos, Chrystal
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
196 TLR9-activated B cells directly license adoptively transferred CD8+ T cells with potent tumor immunity
Smith, Aubrey, Knochelmann, Hannah, Wyatt, Megan, RIvera, Guillermo Rangel, Ware, Brandon, Reyes, Amalia Rivera, Dwyer, Connor, Neskey, David, Rubinstein, Mark, Liu, Bei, Thaxton, Jessica, Bartee, Eric, Paulos, Chrystal
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article