Identification of the MEK1(F129L) activating mutation as a potential mechanism of acquired resistance to MEK inhibition in human cancers carrying the B-RafV600E mutation
Wang, Huisheng, Daouti, Sherif, Li, Wen-Hui, Wen, Yang, Rizzo, Christine, Higgins, Brian, Packman, Kathryn, Rosen, Neal, Boylan, John F, Heimbrook, David, Niu, Huifeng
Published in Cancer research (Chicago, Ill.) (15.08.2011)
Published in Cancer research (Chicago, Ill.) (15.08.2011)
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Journal Article
Identification of the MEK1(F129L) Activating Mutation as a Potential Mechanism of Acquired Resistance to MEK Inhibition in Human Cancers Carrying the B-Raf V600E Mutation
HUISHENG WANG, DAOUTI, Sherif, HUIFENG NIU, LI, Wen-Hui, YANG WEN, RIZZO, Christine, HIGGINS, Brian, PACKMAN, Kathryn, ROSEN, Neal, BOYLAN, John F, HEIMBROOK, David
Published in Cancer research (Chicago, Ill.) (15.08.2011)
Published in Cancer research (Chicago, Ill.) (15.08.2011)
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Journal Article
Quality Indicators Targeting Low-Value Clinical Practices in Trauma Care
Moore, Lynne, Bérubé, Mélanie, Tardif, Pier-Alexandre, Lauzier, François, Turgeon, Alexis, Cameron, Peter, Champion, Howard, Yanchar, Natalie, Lecky, Fiona, Kortbeek, John, Evans, David, Mercier, Éric, Archambault, Patrick, Lamontagne, François, Gabbe, Belinda, Paquet, Jérôme, Razek, Tarek, Stelfox, Henry Thomas
Published in JAMA surgery (01.06.2022)
Published in JAMA surgery (01.06.2022)
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Derivation and validation of actionable quality indicators targeting reductions in complications for injury admissions
Idriss-Hassan, Abakar, Bérubé, Mélanie, Belcaïd, Amina, Clément, Julien, Bourgeois, Gilles, Rizzo, Christine, Neveu, Xavier, Soltana, Kahina, Thakore, Jaimini, Moore, Lynne
Published in European journal of trauma and emergency surgery (Munich : 2007) (01.04.2022)
Published in European journal of trauma and emergency surgery (Munich : 2007) (01.04.2022)
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High tumor levels of IL6 and IL8 abrogate preclinical efficacy of the γ-secretase inhibitor, RO4929097
He, Wei, Luistro, Leopoldo, Carvajal, Daisy, Smith, Melissa, Nevins, Tom, Yin, Xuefeng, Cai, James, Higgins, Brian, Kolinsky, Kenneth, Rizzo, Christine, Packman, Kathryn, Heimbrook, David, Boylan, John F.
Published in Molecular oncology (01.06.2011)
Published in Molecular oncology (01.06.2011)
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Preclinical in vivo evaluation of efficacy, pharmacokinetics, and pharmacodynamics of a novel MEK1/2 kinase inhibitor RO5068760 in multiple tumor models
Daouti, Sherif, Higgins, Brian, Kolinsky, Kenneth, Packman, Kathryn, Wang, Huisheng, Rizzo, Christine, Moliterni, John, Huby, Nicholas, Fotouhi, Nader, Liu, Mei, Goelzer, Petra, Sandhu, Harpreet K, Li, Jia Kui, Railkar, Aruna, Heimbrook, David, Niu, Huifeng
Published in Molecular cancer therapeutics (01.01.2010)
Published in Molecular cancer therapeutics (01.01.2010)
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Abstract A247: Preclinical antitumor activity of the MEK inhibitor RO5068760 in human tumor xenograft models
Brian, Higgins, Kolinsky, Kenneth, Daouti, Sherif, Rizzo, Christine, Wang, Huisheng, Huby, Nicholas, Niu, Huifeng, Packman, Kathryn
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Abstract 5036: Activating MEK1(F129L) mutation as a potential mechanism of acquired resistance to MEK inhibition in human cancers carrying the B-RafV600E mutation
Niu, Huifeng, Wang, Huisheng, Daouti, Sherif, Li, Wen-Hui, Wen, Yang, Rizzo, Christine, Higgins, Brian, Packman, Kathryn, Rosen, Neal, Boylan, John F., Heimbrook, David
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 1370: RO5323441, a humanized monoclonal antibody against the placenta growth factor, blocks PlGF-induced VEGFR-1 phosphorylation in vitro and tumor growth in vivo
Rizzo, Christine, Yin, Xuefeng Yin, Packman, Kathryn, Higgins, Brian, Schnueriger, Alfred, Thomas, Markus, Weidner, Michael, Heimbrook, Dave, Simcox, Mary Ellen C.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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LETTERS
Maurelli, Theresa, Arcery, Rich, Dorn-Rizzo, Christine, Bilawsky, Bernard A, Huzar, Lorraine, Maher, William L
Published in Newsday (11.05.2008)
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Published in Newsday (11.05.2008)
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