A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank
Qian, Junyang, Tanigawa, Yosuke, Du, Wenfei, Aguirre, Matthew, Chang, Chris, Tibshirani, Robert, Rivas, Manuel A, Hastie, Trevor
Published in PLoS genetics (23.10.2020)
Published in PLoS genetics (23.10.2020)
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Significant sparse polygenic risk scores across 813 traits in UK Biobank
Tanigawa, Yosuke, Qian, Junyang, Venkataraman, Guhan, Justesen, Johanne Marie, Li, Ruilin, Tibshirani, Robert, Hastie, Trevor, Rivas, Manuel A
Published in PLoS genetics (24.03.2022)
Published in PLoS genetics (24.03.2022)
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A cross-population atlas of genetic associations for 220 human phenotypes
Sakaue, Saori, Kanai, Masahiro, Tanigawa, Yosuke, Karjalainen, Juha, Kurki, Mitja, Koshiba, Seizo, Narita, Akira, Konuma, Takahiro, Yamamoto, Kenichi, Akiyama, Masato, Ishigaki, Kazuyoshi, Suzuki, Akari, Suzuki, Ken, Obara, Wataru, Yamaji, Ken, Takahashi, Kazuhisa, Asai, Satoshi, Takahashi, Yasuo, Suzuki, Takao, Shinozaki, Nobuaki, Yamaguchi, Hiroki, Minami, Shiro, Murayama, Shigeo, Yoshimori, Kozo, Nagayama, Satoshi, Obata, Daisuke, Higashiyama, Masahiko, Masumoto, Akihide, Koretsune, Yukihiro, Ito, Kaoru, Terao, Chikashi, Yamauchi, Toshimasa, Komuro, Issei, Kadowaki, Takashi, Tamiya, Gen, Yamamoto, Masayuki, Nakamura, Yusuke, Kubo, Michiaki, Murakami, Yoshinori, Yamamoto, Kazuhiko, Kamatani, Yoichiro, Palotie, Aarno, Rivas, Manuel A., Daly, Mark J., Matsuda, Koichi, Okada, Yukinori
Published in Nature genetics (01.10.2021)
Published in Nature genetics (01.10.2021)
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Genetics of 35 blood and urine biomarkers in the UK Biobank
Sinnott-Armstrong, Nasa, Tanigawa, Yosuke, Amar, David, Mars, Nina, Benner, Christian, Aguirre, Matthew, Venkataraman, Guhan Ram, Wainberg, Michael, Ollila, Hanna M., Kiiskinen, Tuomo, Havulinna, Aki S., Pirruccello, James P., Qian, Junyang, Shcherbina, Anna, Rodriguez, Fatima, Assimes, Themistocles L., Agarwala, Vineeta, Tibshirani, Robert, Hastie, Trevor, Ripatti, Samuli, Pritchard, Jonathan K., Daly, Mark J., Rivas, Manuel A.
Published in Nature genetics (01.02.2021)
Published in Nature genetics (01.02.2021)
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Testing for an unusual distribution of rare variants
Neale, Benjamin M, Rivas, Manuel A, Voight, Benjamin F, Altshuler, David, Devlin, Bernie, Orho-Melander, Marju, Kathiresan, Sekar, Purcell, Shaun M, Roeder, Kathryn, Daly, Mark J
Published in PLoS genetics (01.03.2011)
Published in PLoS genetics (01.03.2011)
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Assessing Digital Phenotyping to Enhance Genetic Studies of Human Diseases
DeBoever, Christopher, Tanigawa, Yosuke, Aguirre, Matthew, McInnes, Greg, Lavertu, Adam, Rivas, Manuel A.
Published in American journal of human genetics (07.05.2020)
Published in American journal of human genetics (07.05.2020)
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Journal Article
Phenome-wide Burden of Copy-Number Variation in the UK Biobank
Aguirre, Matthew, Rivas, Manuel A., Priest, James
Published in American journal of human genetics (01.08.2019)
Published in American journal of human genetics (01.08.2019)
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Journal Article
Opportunities and challenges for transcriptome-wide association studies
Wainberg, Michael, Sinnott-Armstrong, Nasa, Mancuso, Nicholas, Barbeira, Alvaro N., Knowles, David A., Golan, David, Ermel, Raili, Ruusalepp, Arno, Quertermous, Thomas, Hao, Ke, Björkegren, Johan L. M., Im, Hae Kyung, Pasaniuc, Bogdan, Rivas, Manuel A., Kundaje, Anshul
Published in Nature genetics (01.04.2019)
Published in Nature genetics (01.04.2019)
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The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease
Moutsianas, Loukas, Agarwala, Vineeta, Fuchsberger, Christian, Flannick, Jason, Rivas, Manuel A, Gaulton, Kyle J, Albers, Patrick K, McVean, Gil, Boehnke, Michael, Altshuler, David, McCarthy, Mark I
Published in PLoS genetics (01.04.2015)
Published in PLoS genetics (01.04.2015)
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Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide
Ruderfer, Douglas M., Walsh, Colin G., Aguirre, Matthew W., Tanigawa, Yosuke, Ribeiro, Jessica D., Franklin, Joseph C., Rivas, Manuel A.
Published in Molecular psychiatry (01.10.2020)
Published in Molecular psychiatry (01.10.2020)
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Journal Article
Mortality and survival in systemic sclerosis: Systematic review and meta-analysis
Rubio-Rivas, Manuel, MD, Royo, Cristina, MD, Simeón, Carmen Pilar, MD, PhD, Corbella, Xavier, MD, PhD, Fonollosa, Vicent, MD, PhD
Published in Seminars in arthritis and rheumatism (01.10.2014)
Published in Seminars in arthritis and rheumatism (01.10.2014)
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Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank
Wainberg, Michael, Jones, Samuel E, Beaupre, Lindsay Melhuish, Hill, Sean L, Felsky, Daniel, Rivas, Manuel A, Lim, Andrew S P, Ollila, Hanna M, Tripathy, Shreejoy J
Published in PLoS medicine (12.10.2021)
Published in PLoS medicine (12.10.2021)
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Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study
Wainberg, Michael, Mahajan, Anubha, Kundaje, Anshul, McCarthy, Mark I, Ingelsson, Erik, Sinnott-Armstrong, Nasa, Rivas, Manuel A
Published in PLoS medicine (10.12.2019)
Published in PLoS medicine (10.12.2019)
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A framework for variation discovery and genotyping using next-generation DNA sequencing data
DePristo, Mark A, Banks, Eric, Poplin, Ryan, Garimella, Kiran V, Maguire, Jared R, Hartl, Christopher, Philippakis, Anthony A, del Angel, Guillermo, Rivas, Manuel A, Hanna, Matt, McKenna, Aaron, Fennell, Tim J, Kernytsky, Andrew M, Sivachenko, Andrey Y, Cibulskis, Kristian, Gabriel, Stacey B, Altshuler, David, Daly, Mark J
Published in Nature genetics (01.05.2011)
Published in Nature genetics (01.05.2011)
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Journal Article
Time trajectories in the transcriptomic response to exercise - a meta-analysis
Amar, David, Lindholm, Malene E., Norrbom, Jessica, Wheeler, Matthew T., Rivas, Manuel A., Ashley, Euan A.
Published in Nature communications (09.06.2021)
Published in Nature communications (09.06.2021)
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Journal Article
GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background
Sinnott-Armstrong, Nasa, Naqvi, Sahin, Rivas, Manuel, Pritchard, Jonathan K
Published in eLife (15.02.2021)
Published in eLife (15.02.2021)
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Journal Article
Sex-specific genetic effects across biomarkers
Flynn, Emily, Tanigawa, Yosuke, Rodriguez, Fatima, Altman, Russ B, Sinnott-Armstrong, Nasa, Rivas, Manuel A
Published in European journal of human genetics : EJHG (01.01.2021)
Published in European journal of human genetics : EJHG (01.01.2021)
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