Quantitative and functional characterisation of extracellular vesicles after passive loading with hydrophobic or cholesterol-tagged small molecules
Tréton, Gwenola, Sayer, Claudia, Schürz, Melanie, Jaritsch, Maria, Müller, Anna, Matea, Cristian-Tudor, Stanojlovic, Vesna, Melo-Benirschke, Heloisa, Be, Celine, Krembel, Caroline, Rodde, Stephane, Haffke, Matthias, Hintermann, Samuel, Marzinzik, Andreas, Ripoche, Sébastien, Blöchl, Constantin, Hollerweger, Julia, Auer, Daniela, Cabrele, Chiara, Huber, Christian G., Hintersteiner, Martin, Wagner, Trixie, Lingel, Andreas, Meisner-Kober, Nicole
Published in Journal of controlled release (01.09.2023)
Published in Journal of controlled release (01.09.2023)
Get full text
Journal Article
2‑Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4
Knoepfel, Thomas, Furet, Pascal, Mah, Robert, Buschmann, Nicole, Leblanc, Catherine, Ripoche, Sebastien, Graus-Porta, Diana, Wartmann, Markus, Galuba, Inga, Fairhurst, Robin A
Published in ACS medicinal chemistry letters (08.03.2018)
Published in ACS medicinal chemistry letters (08.03.2018)
Get full text
Journal Article
Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4
Fairhurst, Robin A, Knoepfel, Thomas, Buschmann, Nicole, Leblanc, Catherine, Mah, Robert, Todorov, Milen, Nimsgern, Pierre, Ripoche, Sebastien, Niklaus, Michel, Warin, Nicolas, Luu, Van Huy, Madoerin, Mario, Wirth, Jasmin, Graus-Porta, Diana, Weiss, Andreas, Kiffe, Michael, Wartmann, Markus, Kinyamu-Akunda, Jacqueline, Sterker, Dario, Stamm, Christelle, Adler, Flavia, Buhles, Alexandra, Schadt, Heiko, Couttet, Philippe, Blank, Jutta, Galuba, Inga, Trappe, Jörg, Voshol, Johannes, Ostermann, Nils, Zou, Chao, Berghausen, Jörg, Del Rio Espinola, Alberto, Jahnke, Wolfgang, Furet, Pascal
Published in Journal of medicinal chemistry (12.11.2020)
Published in Journal of medicinal chemistry (12.11.2020)
Get full text
Journal Article
Identification of NVP-CLR457 as an Orally Bioavailable Non-CNS-Penetrant pan-Class IA Phosphoinositol-3-Kinase Inhibitor
Fairhurst, Robin A., Furet, Pascal, Imbach-Weese, Patricia, Stauffer, Frédéric, Rueeger, Heinrich, McCarthy, Clive, Ripoche, Sebastien, Oswald, Susanne, Arnaud, Bertrand, Jary, Aline, Maira, Michel, Schnell, Christian, Guthy, Daniel A., Wartmann, Markus, Kiffe, Michael, Desrayaud, Sandrine, Blasco, Francesca, Widmer, Toni, Seiler, Frank, Gutmann, Sascha, Knapp, Mark, Caravatti, Giorgio
Published in Journal of medicinal chemistry (23.06.2022)
Published in Journal of medicinal chemistry (23.06.2022)
Get full text
Journal Article
Correction to “2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4”
Knoepfel, Thomas, Furet, Pascal, Mah, Robert, Buschmann, Nicole, Leblanc, Catherine, Ripoche, Sebastien, Graus-Porta, Diana, Wartmann, Markus, Galuba, Inga, Fairhurst, Robin A
Published in ACS medicinal chemistry letters (12.11.2020)
Published in ACS medicinal chemistry letters (12.11.2020)
Get full text
Journal Article
Discovery, X-ray structure and CPP-conjugation enabled uptake of / macrocyclic peptide inhibitors
Schneider, Anselm F. L, Kallen, Joerg, Ottl, Johannes, Reid, Patrick C, Ripoche, Sebastien, Ruetz, Stephan, Stachyra, Therese-Marie, Hintermann, Samuel, Dumelin, Christoph E, Hackenberger, Christian P. R, Marzinzik, Andreas L
Published in RSC chemical biology (01.12.2021)
Published in RSC chemical biology (01.12.2021)
Get full text
Journal Article
Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors
Schneider, Anselm F L, Kallen, Joerg, Ottl, Johannes, Reid, Patrick C, Ripoche, Sebastien, Ruetz, Stephan, Stachyra, Therese-Marie, Hintermann, Samuel, Dumelin, Christoph E, Hackenberger, Christian P R, Marzinzik, Andreas L
Published in RSC chemical biology (02.12.2021)
Published in RSC chemical biology (02.12.2021)
Get full text
Journal Article
RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
FURET PASCAL, RIPOCHE SEBASTIEN, XIONG JING, NIMSGERN PIERRE, LIAO LV, LEBLANC CATHERINE, WANG CAN, ZHAO XIANGLIN, MAH ROBERT, FAIRHURST ROBIN ALEC, KNOEPFEL THOMAS, HAN BO, BUSCHMANN NICOLE
Year of Publication 29.06.2016
Get full text
Year of Publication 29.06.2016
Patent
RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
BUSCHMANN, NICOLE, MAH, ROBERT, FAIRHURST, ROBIN ALEC, NIMSGERN, PIERRE, RIPOCHE, SEBASTIEN, LEBLANC, CATHERINE, LIAO, LV, KNOPFEL, THOMAS, HAN, BO, ZHAO, XIANGLIN, XIONG, JING, FURET, PASCAL, WANG, CAN
Year of Publication 28.09.2021
Get full text
Year of Publication 28.09.2021
Patent
USE OF RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
FURET, Pascal, NIMSGERN, Pierre, KNÖPFEL, Thomas, XIONG, Jing, WANG, Can, FAIRHURST, Robin Alec, HAN, Bo, ZHAO, Xianglin, LIAO, Lv, MAH, Robert, BUSCHMANN, Nicole, RIPOCHE, Sebastien, LEBLANC, Catherine
Year of Publication 14.03.2019
Get full text
Year of Publication 14.03.2019
Patent
RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
FURET, Pascal, NIMSGERN, Pierre, KNÖPFEL, Thomas, XIONG, Jing, WANG, Can, FAIRHURST, Robin Alec, HAN, Bo, ZHAO, Xianglin, MAH, Robert, LIAO, Lv, BUSCHMANN, Nicole, RIPOCHE, Sebastien, LEBLANC, Catherine
Year of Publication 02.05.2018
Get full text
Year of Publication 02.05.2018
Patent
USE OF RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
HAEFLIGER, CAROLINA, KNÖPFEL, THOMAS, BUSCHMANN, NICOLE, MAH, ROBERT, FAIRHURST, ROBIN ALEC, NIMSGERN, PIERRE, RIPOCHE, SEBASTIEN, LEBLANC, CATHERINE, LIAO, LV, PORTER, DALE, MURAKAMI, MASATO, HAN, BO, ZHAO, XIANGLIN, WANG, YOUZHEN, PALMER, MICHAEL, WEISS, ANDREAS, XIONG, JING, FURET, PASCAL, WANG, CAN, GRAUS PORTA, DIANA
Year of Publication 31.03.2020
Get full text
Year of Publication 31.03.2020
Patent
Ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors
Wang Can, Furet Pascal, Han Bo, Fairhurst Robin Alec, Nimsgern Pierre, Liao Lv, Ripoche Sebastien, Zhao Xianglin, Leblanc Catherine, Mah Robert, Xiong Jing, Buschmann Nicole, Knöpfel Thomas
Year of Publication 20.02.2018
Get full text
Year of Publication 20.02.2018
Patent
Use of ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors
Furet, Pascal, Graus Porta, Diana, Leblanc, Catherine, Palmer, Michael, Porter, Dale, Han, Bo, Knöpfel, Thomas, Nimsgern, Pierre, Wang, Can, Fairhurst, Robin Alec, Xiong, Jing, Mah, Robert, Murakami, Masato, Ripoche, Sebastien, Weiss, Andreas, Zhao, Xianglin, Liao, Lv, Wang, Youzhen, Haefliger, Carolina, Buschmann, Nicole
Year of Publication 17.12.2019
Get full text
Year of Publication 17.12.2019
Patent
RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
BUSCHMANN, NICOLE, KNÖPFEL, THOMAS, MAH, ROBERT, FAIRHURST, ROBIN ALEC, NIMSGERN, PIERRE, RIPOCHE, SEBASTIEN, LEBLANC, CATHERINE, LIAO, LV, HAN, BO, ZHAO, XIANGLIN, XIONG, JING, FURET, PASCAL, WANG, CAN
Year of Publication 31.10.2018
Get full text
Year of Publication 31.10.2018
Patent
USE OF RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
FURET, Pascal, NIMSGERN, Pierre, GRAUS PORTA, Diana, MURAKAMI, Masato, PALMER, Michael, KNÖPFEL, Thomas, XIONG, Jing, WANG, Can, HAN, Bo, ZHAO, Xianglin, LIAO, Lv, MAH, Robert, WANG, Youzhen, FAIRHURST, Robin, Alec, PORTER, Dale, BUSCHMANN, Nicole, RIPOCHE, Sebastien, HAEFLIGER, Carolina, WEISS, Andreas, LEBLANC, Catherine
Year of Publication 28.08.2019
Get full text
Year of Publication 28.08.2019
Patent
USE OF RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
FURET, Pascal, NIMSGERN, Pierre, GRAUS PORTA, Diana, MURAKAMI, Masato, KNOPFEL, Thomas, PALMER, Michael, XIONG, Jing, WANG, Can, FAIRHURST, Robin Alec, HAN, Bo, ZHAO, Xianglin, LIAO, Lv, MAH, Robert, WANG, Youzhen, BUSCHMANN, Nicole, PORTER, Dale, RIPOCHE, Sebastien, HAEFLIGER, Carolina, WEISS, Andreas, LEBLANC, Catherine
Year of Publication 01.08.2019
Get full text
Year of Publication 01.08.2019
Patent
RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
LV LIAO, PIERRE NIMSGERN, BO HAN, THOMAS KNÖPFEL, XIANGLIN ZHAO, ROBIN ALEC FAIRHURST, JING XIONG, CATHERINE LEBLANC, ROBERT MAH, SEBASTIEN RIPOCHE, PASCAL FURET, NICOLE BUSCHMANN, CAN WANG
Year of Publication 26.07.2018
Get full text
Year of Publication 26.07.2018
Patent
RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS
FURET, Pascal, NIMSGERN, Pierre, KNÖPFEL, Thomas, XIONG, Jing, WANG, Can, FAIRHURST, Robin Alec, HAN, Bo, ZHAO, Xianglin, LIAO, Lv, MAH, Robert, BUSCHMANN, Nicole, RIPOCHE, Sebastien, LEBLANC, Catherine
Year of Publication 05.07.2017
Get full text
Year of Publication 05.07.2017
Patent