Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity
Nakayama, Yumi, Kosek, Jolanta, Capone, Lori, Hur, Eun Mi, Schafer, Peter H, Ringheim, Garth E
Published in The Journal of immunology (1950) (01.10.2017)
Published in The Journal of immunology (1950) (01.10.2017)
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Cereblon modulator iberdomide induces degradation of the transcription factors Ikaros and Aiolos: immunomodulation in healthy volunteers and relevance to systemic lupus erythematosus
Schafer, Peter H, Ye, Ying, Wu, Lei, Kosek, Jolanta, Ringheim, Garth, Yang, Zhihong, Liu, Liangang, Thomas, Michael, Palmisano, Maria, Chopra, Rajesh
Published in Annals of the rheumatic diseases (01.10.2018)
Published in Annals of the rheumatic diseases (01.10.2018)
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Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study
Schafer, Peter H., Kivitz, Alan J., Ma, Jianglin, Korish, Shimon, Sutherland, Donna, Li, Li, Azaryan, Ada, Kosek, Jolanta, Adams, Mary, Capone, Lori, Hur, Eun Mi, Hough, Douglas R., Ringheim, Garth E.
Published in Rheumatology and therapy. (01.03.2020)
Published in Rheumatology and therapy. (01.03.2020)
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Teriflunomide attenuates immunopathological changes in the dark agouti rat model of experimental autoimmune encephalomyelitis
Ringheim, Garth E, Lee, Lan, Laws-Ricker, Lynn, Delohery, Tomas, Liu, Li, Zhang, Donghui, Colletti, Nicholas, Soos, Timothy J, Schroeder, Kendra, Fanelli, Barbara, Tian, Nian, Arendt, Christopher W, Iglesias-Bregna, Deborah, Petty, Margaret, Ji, Zhongqi, Qian, George, Gaur, Rajula, Weinstock, Daniel, Cavallo, Jean, Telsinskas, Juventas, McMonagle-Strucko, Kathleen
Published in Frontiers in neurology (01.01.2013)
Published in Frontiers in neurology (01.01.2013)
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First‐in‐Human (FIH), Single‐ and Multiple‐Ascending‐Dose (SAD/MAD) studies in healthy subjects of E2511, a novel tropomyosin receptor kinase a (TrkA) positive allosteric modulator (PAM)
Aceves, Pau, Hall, Nancy, Dayal, Satish, Yagi, Takuya, Chang, Julia, Mikamoto, Masaki, Ringheim, Garth E, Takesuya, Tomioka, Hiramatsu, Naoki, Gordon, Robert, Giorgi, Luigi
Published in Alzheimer's & dementia (01.06.2023)
Published in Alzheimer's & dementia (01.06.2023)
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Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex
Ringheim, Garth E, Szczepanik, Ann Marie, Petko, Wayne, Burgher, Kendra L, Zhu, Sheng Zu, Chao, Chun C
Published in Brain research. Molecular brain research. (30.03.1998)
Published in Brain research. Molecular brain research. (30.03.1998)
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Discovery of the Selective Protein Kinase C-theta Kinase Inhibitor, CC-90005
Papa, Patrick, Whitefield, Brandon, Mortensen, Deborah S., Cashion, Dan, Huang, Dehua, Torres, Eduardo, Parnes, Jason, Sapienza, John, Hansen, Joshua, Correa, Matthew, Delgado, Mercedes, Harris, Roy, Hegde, Sayee, Norris, Stephen, Bahmanyar, Sogole, Plantevin-Krenitsky, Veronique, Liu, Zheng, Leftheris, Katerina, Kulkarni, Ashutosh, Bennett, Brydon, Hur, Eun Mi, Ringheim, Garth, Khambatta, Godrej, Chan, Henry, Muir, Jeffrey, Blease, Kate, Burnett, Kelven, LeBrun, Laurie, Morrison, Lisa, Celeridad, Maria, Khattri, Roli, Cathers, Brian E.
Published in Journal of medicinal chemistry (26.08.2021)
Published in Journal of medicinal chemistry (26.08.2021)
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PD-1 결합 단백질을 사용하는 면역 질환의 치료 방법
CHAN HENRY H, LEUNG MONICA, RINGHEIM GARTH E, HUR EUN MI, SCHAFER PETER H, KHATTRI ROLI
Year of Publication 19.06.2019
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Year of Publication 19.06.2019
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