Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease
Mapuskar, Kranti A, Wen, Hsiang, Holanda, Danniele G, Rastogi, Prerna, Steinbach, Emily, Han, Rachel, Coleman, Mitchell C, Attanasio, Massimo, Riley, Dennis P, Spitz, Douglas R, Allen, Bryan G, Zepeda-Orozco, Diana
Published in Redox biology (01.01.2019)
Published in Redox biology (01.01.2019)
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Journal Article
Mitochondrial Superoxide Increases Age-Associated Susceptibility of Human Dermal Fibroblasts to Radiation and Chemotherapy
Mapuskar, Kranti A, Flippo, Kyle H, Schoenfeld, Joshua D, Riley, Dennis P, Strack, Stefan, Hejleh, Taher Abu, Furqan, Muhammad, Monga, Varun, Domann, Frederick E, Buatti, John M, Goswami, Prabhat C, Spitz, Douglas R, Allen, Bryan G
Published in Cancer research (Chicago, Ill.) (15.09.2017)
Published in Cancer research (Chicago, Ill.) (15.09.2017)
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Journal Article
Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury
Mapuskar, Kranti A., Steinbach, Emily J., Zaher, Amira, Riley, Dennis P., Beardsley, Robert A., Keene, Jeffery L., Holmlund, Jon T., Anderson, Carryn M., Zepeda-Orozco, Diana, Buatti, John M., Spitz, Douglas R., Allen, Bryan G.
Published in Antioxidants (24.08.2021)
Published in Antioxidants (24.08.2021)
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Journal Article
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies
Muscoli, Carolina, Cuzzocrea, Salvatore, Riley, Dennis P, Zweier, Jay L, Thiemermann, Christoph, Wang, Zhi‐Qiang, Salvemini, Daniela
Published in British journal of pharmacology (01.10.2003)
Published in British journal of pharmacology (01.10.2003)
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Journal Article
Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H₂O₂-Dependent Manner
Heer, Collin D, Davis, Andrew B, Riffe, David B, Wagner, Brett A, Falls, Kelly C, Allen, Bryan G, Buettner, Garry R, Beardsley, Robert A, Riley, Dennis P, Spitz, Douglas R
Published in Antioxidants (19.01.2018)
Published in Antioxidants (19.01.2018)
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Journal Article
Inactivation of Catecholamines by Superoxide Gives New Insights on the Pathogenesis of Septic Shock
Macarthur, Heather, Westfall, Thomas C., Riley, Dennis P., Misko, Thomas P., Salvemini, Daniela
Published in Proceedings of the National Academy of Sciences - PNAS (15.08.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (15.08.2000)
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Journal Article
O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate
Schoenfeld, Joshua D., Sibenaller, Zita A., Mapuskar, Kranti A., Wagner, Brett A., Cramer-Morales, Kimberly L., Furqan, Muhammad, Sandhu, Sonia, Carlisle, Thomas L., Smith, Mark C., Abu Hejleh, Taher, Berg, Daniel J., Zhang, Jun, Keech, John, Parekh, Kalpaj R., Bhatia, Sudershan, Monga, Varun, Bodeker, Kellie L., Ahmann, Logan, Vollstedt, Sandy, Brown, Heather, Shanahan Kauffman, Erin P., Schall, Mary E., Hohl, Ray J., Clamon, Gerald H., Greenlee, Jeremy D., Howard, Matthew A., Schultz, Michael K., Smith, Brian J., Riley, Dennis P., Domann, Frederick E., Cullen, Joseph J., Buettner, Garry R., Buatti, John M., Spitz, Douglas R., Allen, Bryan G.
Published in Cancer cell (10.04.2017)
Published in Cancer cell (10.04.2017)
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Journal Article
Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403
Salvemini, Daniela, Mazzon, Emanuela, Dugo, Laura, Riley, Dennis P, Serraino, Ivana, Caputi, Achille P, Cuzzocrea, Salvatore
Published in British journal of pharmacology (01.02.2001)
Published in British journal of pharmacology (01.02.2001)
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Journal Article
Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion
Cuzzocrea, Salvatore, Mazzon, Emanuela, Dugo, Laura, Caputi, Achille P, Aston, Karl, Riley, Dennis P, Salvemini, Daniela
Published in British journal of pharmacology (01.01.2001)
Published in British journal of pharmacology (01.01.2001)
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Journal Article
Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide
Sishc, Brock J, Ding, Lianghao, Nam, Taek-Keun, Heer, Collin D, Rodman, Samuel N, Schoenfeld, Joshua D, Fath, Melissa A, Saha, Debabrata, Pulliam, Casey F, Langen, Britta, Beardsley, Robert A, Riley, Dennis P, Keene, Jeffery L, Spitz, Douglas R, Story, Michael D
Published in Science translational medicine (12.05.2021)
Published in Science translational medicine (12.05.2021)
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Journal Article
Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury
Cuzzocrea, S, Riley, D P, Caputi, A P, Salvemini, D
Published in Pharmacological reviews (01.03.2001)
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Published in Pharmacological reviews (01.03.2001)
Journal Article
Sod mimetics are coming of age
Salvemini, Daniela, Riley, Dennis P, Cuzzocrea, Salvatore
Published in Nature reviews. Drug discovery (01.05.2002)
Published in Nature reviews. Drug discovery (01.05.2002)
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Journal Article
Toward the Rational Design of Superoxide Dismutase Mimics: Mechanistic Studies for the Elucidation of Substituent Effects on the Catalytic Activity of Macrocyclic Manganese(II) Complexes
Riley, Dennis P, Lennon, Patrick J, Neumann, William L, Weiss, Randy H
Published in Journal of the American Chemical Society (16.07.1997)
Published in Journal of the American Chemical Society (16.07.1997)
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Journal Article
Superoxide mediates acute liver injury in irradiated mice lacking sirtuin 3
Coleman, Mitchell C, Olivier, Alicia K, Jacobus, James A, Mapuskar, Kranti A, Mao, Gaowei, Martin, Sean M, Riley, Dennis P, Gius, David, Spitz, Douglas R
Published in Antioxidants & redox signaling (20.03.2014)
Published in Antioxidants & redox signaling (20.03.2014)
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Journal Article
The contribution of oxidative stress in apoptosis of human-cultured astroglial cells induced by supernatants of HIV-1-infected macrophages
Mollace, Vincenzo, Salvemini, Daniela, Riley, Dennis P., Muscoli, Carolina, Iannone, Michelangelo, Granato, Teresa, Masuelli, Laura, Modesti, Andrea, Rotiroti, Domenicantonio, Nisticó, Robert, Bertoli, Ada, Perno, Carlo‐Federico, Aquaro, Stefano
Published in Journal of leukocyte biology (01.01.2002)
Published in Journal of leukocyte biology (01.01.2002)
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Journal Article
Synthesis, Characterization, and Stability of Manganese(II) C-Substituted 1,4,7,10,13-Pentaazacyclopentadecane Complexes Exhibiting Superoxide Dismutase Activity
Riley, Dennis P, Henke, Susan L, Lennon, Patrick J, Weiss, Randy H, Neumann, William L, Rivers, Willie J, Aston, Karl W, Sample, Kirby R, Rahman, Hayat, Ling, Chaur-Sun, Shieh, Jeng-Jong, Busch, Daryle H
Published in Inorganic chemistry (28.08.1996)
Published in Inorganic chemistry (28.08.1996)
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Journal Article
A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats
Salvemini, Daniela, Wang, Zhi-Qiang, Zweier, Jay L., Samouilov, Alexandre, Macarthur, Heather, Misko, Thomas P., Currie, Mark G., Cuzzocrea, Salvatore, Sikorski, James A., Riley, Dennis P.
Published in Science (American Association for the Advancement of Science) (08.10.1999)
Published in Science (American Association for the Advancement of Science) (08.10.1999)
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Journal Article
Iron(III) Complexes as Superoxide Dismutase Mimics: Synthesis, Characterization, Crystal Structure, and Superoxide Dismutase (SOD) Activity of Iron(III) Complexes Containing Pentaaza Macrocyclic Ligands
Zhang, DeLong, Busch, Daryle H, Lennon, Patrick L, Weiss, Randy H, Neumann, William L, Riley, Dennis P
Published in Inorganic chemistry (09.03.1998)
Published in Inorganic chemistry (09.03.1998)
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Journal Article