Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death
Jo, Hakryul, Mondal, Subhanjan, Tan, Dewar, Nagata, Eiichiro, Takizawa, Shunya, Sharma, Alok K, Hou, Qingming, Shanmugasundaram, Kumaran, Prasad, Amit, Tung, Joe K, Tejeda, Alexander O, Man, Hengye, Rigby, Alan C, Luo, Hongbo R
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2012)
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Pilot Study of Extracorporeal Removal of Soluble Fms-Like Tyrosine Kinase 1 in Preeclampsia
THADHANI, Ravi, KISNER, Tuelay, HEMPHILL, Linda, RIGBY, Alan C, KHEDKAR, Santosh, LINDNER, Tom H, MALLMANN, Peter, STEPAN, Holger, ANANTH KARUMANCHI, S, BENZING, Thomas, HAGMANN, Henning, BOSSUNG, Verena, NOACK, Stefanie, SCHAARSCHMIDT, Wiebke, JANK, Alexander, KRIBS, Angela, COMELY, Oliver A, KREYSSIG, Claudia
Published in Circulation (New York, N.Y.) (23.08.2011)
Published in Circulation (New York, N.Y.) (23.08.2011)
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Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders
Bezzerides, Vassilios J., Zhang, Aifeng, Xiao, Ling, Simonson, Bridget, Khedkar, Santosh A., Baba, Shiro, Ottaviano, Filomena, Lynch, Stacey, Hessler, Katherine, Rigby, Alan C., Milan, David, Das, Saumya, Rosenzweig, Anthony
Published in Scientific reports (23.03.2017)
Published in Scientific reports (23.03.2017)
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Journal Article
RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription
Gerald, Damien, Adini, Irit, Shechter, Sharon, Perruzzi, Carole, Varnau, Joseph, Hopkins, Benjamin, Kazerounian, Shiva, Kurschat, Peter, Blachon, Stephanie, Khedkar, Santosh, Bagchi, Mandrita, Sherris, David, Prendergast, George C., Klagsbrun, Michael, Stuhlmann, Heidi, Rigby, Alan C., Nagy, Janice A., Benjamin, Laura E.
Published in Nature communications (27.11.2013)
Published in Nature communications (27.11.2013)
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Journal Article
Optimization of a Novel Mandelamide-Derived Pyrrolopyrimidine Series of PERK Inhibitors
Stokes, Michael E, Surman, Matthew D, Calvo, Veronica, Surguladze, David, Li, An-Hu, Gasparek, Jennifer, Betzenhauser, Matthew, Zhu, Guangyu, Du, Hongwen, Rigby, Alan C, Mulvihill, Mark J
Published in Pharmaceutics (01.10.2022)
Published in Pharmaceutics (01.10.2022)
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Journal Article
Familial Alzheimer's disease mutations alter the stability of the amyloid β-protein monomer folding nucleus
Grant, Marianne A, Lazo, Noel D, Lomakin, Aleksey, Condron, Margaret M, Arai, Hiromi, Yamin, Ghiam, Rigby, Alan C, Teplow, David B
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2007)
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Journal Article
Identification of Novel Non-secosteroidal Vitamin D Receptor Agonists with Potent Cardioprotective Effects and devoid of Hypercalcemia
Khedkar, Santosh A., Samad, Mohammed A., Choudhury, Sangita, Lee, Ji Yoo, Zhang, Dongsheng, Thadhani, Ravi I., Karumanchi, S. Ananth, Rigby, Alan C., Kang, Peter M.
Published in Scientific reports (16.08.2017)
Published in Scientific reports (16.08.2017)
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Journal Article
Solution Structure of the Guanine Nucleotide-binding STAS Domain of SLC26-related SulP Protein Rv1739c from Mycobacterium tuberculosis
Sharma, Alok K., Ye, Liwen, Baer, Christina E., Shanmugasundaram, Kumaran, Alber, Tom, Alper, Seth L., Rigby, Alan C.
Published in The Journal of biological chemistry (11.03.2011)
Published in The Journal of biological chemistry (11.03.2011)
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Journal Article
Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins
Furie, Barbara C, Huang, Mingdong, Rigby, Alan C, Morelli, Xavier, Grant, Marianne A, Huang, Guiqing, Furie, Bruce, Seaton, Barbara
Published in Nature structural & molecular biology (01.09.2003)
Published in Nature structural & molecular biology (01.09.2003)
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Journal Article
Critical role for the Ets transcription factor ELF-1 in the development of tumor angiogenesis
Huang, Xuling, Brown, Courtney, Ni, Weihua, Maynard, Elizabeth, Rigby, Alan C., Oettgen, Peter
Published in Blood (15.04.2006)
Published in Blood (15.04.2006)
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Journal Article
PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors
Stokes, Michael E, Calvo, Veronica, Fujisawa, Sho, Dudgeon, Crissy, Huang, Sharon, Ballal, Nupur, Shen, Leyi, Gasparek, Jennifer, Betzenhauser, Matthew, Taylor, Simon J, Staschke, Kirk A, Rigby, Alan C, Mulvihill, Mark J, Bose, Nandita, Lightcap, Eric S, Surguladze, David
Published in Clinical cancer research (01.12.2023)
Published in Clinical cancer research (01.12.2023)
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Journal Article
Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain
Tan, Kemin, Duquette, Mark, Liu, Jin-huan, Shanmugasundaram, Kumaran, Joachimiak, Andrzej, Gallagher, John T., Rigby, Alan C., Wang, Jia-huai, Lawler, Jack
Published in The Journal of biological chemistry (15.02.2008)
Published in The Journal of biological chemistry (15.02.2008)
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Journal Article
Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator
Thomson, Christopher G., Aicher, Thomas D., Cheng, Weiwei, Du, Hongwen, Dudgeon, Crissy, Li, An-Hu, Li, Baozhong, Lightcap, Eric, Luo, Diheng, Mulvihill, Mark, Pan, Pengwei, Rahemtulla, Benjamin F., Rigby, Alan C., Sherborne, Bradley, Sood, Sanjeev, Surguladze, David, Talbot, Eric P. A., Tameire, Feven, Taylor, Simon, Wang, Yi, Wojnarowicz, Paulina, Xiao, Fenfen, Ramurthy, Savithri
Published in Journal of medicinal chemistry (11.04.2024)
Published in Journal of medicinal chemistry (11.04.2024)
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Journal Article
STAS Domain Structure and Function
Sharma, Alok K., Rigby, Alan C., Alper, Seth L.
Published in Cellular physiology and biochemistry (01.01.2011)
Published in Cellular physiology and biochemistry (01.01.2011)
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Journal Article
Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors
Calvo, Veronica, Surguladze, David, Li, An-Hu, Surman, Matthew D., Malibhatla, Srikanth, Bandaru, Madhavarao, Jonnalagadda, Suresh Krishna, Adarasandi, Ravi, Velmala, Madhusudhan, Singireddi, Durga Rama Prasad, Velpuri, Mahendar, Nareddy, Bhaskar Reddy, Sastry, Visweswara, Mandati, Chiranjeevi, Guguloth, Rambabu, Siddiqui, Shapi, Patil, Basanagoud S., Chad, Elena, Wolfley, Jennifer, Gasparek, Jennifer, Feldman, Kirsten, Betzenhauser, Matthew, Wiens, Brent, Koszelak-Rosenblum, Mary, Zhu, Guangyu, Du, Hongwen, Rigby, Alan C., Mulvihill, Mark J.
Published in Bioorganic & medicinal chemistry letters (01.07.2021)
Published in Bioorganic & medicinal chemistry letters (01.07.2021)
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