Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade
Schmittnaegel, Martina, Rigamonti, Nicolò, Kadioglu, Ece, Cassará, Antonino, Wyser Rmili, Céline, Kiialainen, Anna, Kienast, Yvonne, Mueller, Hans-Joachim, Ooi, Chia-Huey, Laoui, Damya, De Palma, Michele
Published in Science translational medicine (12.04.2017)
Published in Science translational medicine (12.04.2017)
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Journal Article
Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy
Kashyap, Abhishek S., Schmittnaegel, Martina, Rigamonti, Nicolò, Pais-Ferreira, Daniela, Mueller, Philipp, Buchi, Melanie, Ooi, Chia-Huey, Kreuzaler, Matthias, Hirschmann, Petra, Guichard, Alan, Rieder, Natascha, Bill, Ruben, Herting, Frank, Kienast, Yvonne, Dirnhofer, Stefan, Klein, Christian, Hoves, Sabine, Ries, Carola H., Corse, Emily, De Palma, Michele, Zippelius, Alfred
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
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Journal Article
Modulators of arginine metabolism support cancer immunosurveillance
Capuano, Giusy, Rigamonti, Nicolò, Grioni, Matteo, Freschi, Massimo, Bellone, Matteo
Published in BMC immunology (09.01.2009)
Published in BMC immunology (09.01.2009)
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Journal Article
Modulators of Arginine Metabolism Do Not Impact on Peripheral T-Cell Tolerance and Disease Progression in a Model of Spontaneous Prostate Cancer
RIGAMONTI, Nicolo, CAPUANO, Giusy, RICUPITO, Alessia, JACHETTI, Elena, GRIONI, Matteo, GENEROSO, Luca, FRESCHI, Massimo, BELLONE, Matteo
Published in Clinical cancer research (01.03.2011)
Published in Clinical cancer research (01.03.2011)
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Journal Article
Abstract 3251: Fibroblast activation protein (FAP)-selective delivery of CD40 agonistic DARPin®molecule for tumor-localized immune activation
Rigamonti, Nicolo, Schlegel, Anja, Barsin, Sophie, Schwestermann, Jonas, Mangold, Susanne, Kaufmann, Yvonne, Zitt, Christof, Veitonmäki, Niina, Levitsky, Victor, Metz, Clara
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 1073: A tumor-targeted CD40 agonistic DARPin® molecule leading to antitumor activity with limited systemic toxicity
Rigamonti, Nicolo, Jetzer, Sarah, Van der Velden, Niels, Abdelmotaleb, Omar, Barsin, Sophie, Schwestermann, Jonas, Mangold, Susanne, Kaufmann, Yvonne, Bessey, Ralph, Valeri, Andrea, Poulet, Heidi, Zitt, Christof, Trail, Pamela A., Levitsky, Victor, Veitonmäki, Niina, Metz, Clara
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1733: MP0317, a CD40xFAP targeting multi-specific DARPin® therapeutic, drives immune activation and reverts myeloid-mediated T-cell suppression in vitro and ex vivo
Ioannou, Kyriaki, Ragusa, Simone, Roquette, Joanna, Florescu, Ana, Gachechiladze, Mariam, Müller, Eliane, Martinez-Gomez, Julia M., Barsin, Sophie, Jetzer, Sarah, Rigamonti, Nicolo, Domke, Clara, Lekishvili, Tamara, Rommel, Karolin, Tosevski, Ivana, Goubier, Anne, Legenne, Philippe, Kirkin, Vladimir, Levesque, Mitch, Ji, Hong, Kenefeck, Rupert
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
다중특이적 단백질
RIGAMONTI NICOLO, LEVITSKY VICTOR, VEITONMAEKI NIINA ELISABET, DOMKE CLARA, TRAIL SMITH PAMELA ANNA, CALABRO VALERIE PERRINE
Year of Publication 14.02.2023
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Year of Publication 14.02.2023
Patent
Abstract 3645: Preclinical characterization of a multi-specific DARPin molecule targeting PD1 and VEGF
Krieg, Jennifer, Dieter, Schiegg, Joanna, Taylor, Herzog, Christel, Juglair, Laurent, Rigamonti, Nicolo, Mueller, Mischa, Fiedler, Ulrike, Stumpp, Michael Tobias, Snell, Dan
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 4552: Tumor-restricted immune modulation by multispecific molecules from the DARPin toolbox
Fiedler, Ulrike, Reichen, Christian, Taylor, Joanna, Schildknecht, Patricia, Barsin, Sophie, Metz, Clara, Schlegel, Anja, Fontaine, Simon, Villemagne, Denis, Ahlskog, Julia, Kaufmann, Yvonne, Link, Alexander, Rigamonti, Nicolo, Hepp, Julia, Stumpp, Michael T.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 1811: AFVT-2101: A FRα × CD16A bispecific innate cell engager for the treatment of solid tumors
Rigamonti, Nicolo', Schmollinger, Jan, Sandy, Peter, Tomaszowski, Michael, Caslavsky, Josef, Trad, Ahmad, O’Shannessy, Daniel, Siegler, Jana, Gaukel, Eric J., Penston, Daniela, Reusch, Uwe, Johnson, Zoë
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Affibody-mediated retention of the epidermal growth factor receptor in the secretory compartments leads to inhibition of phosphorylation in the kinase domain
Vernet, Erik, Lundberg, Emma, Friedman, Mikaela, Rigamonti, Nicolò, Klausing, Sandra, Nygren, Per-Åke, Gräslund, Torbjörn
Published in New biotechnology (01.09.2009)
Published in New biotechnology (01.09.2009)
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Journal Article
RECOMBINANT CD40 BINDING PROTEINS AND THEIR USE
SCHLEGEL, Anja Christina, RIGAMONTI, Nicolo, CALABRO, Valérie Perrine, DOMKE, Clara
Year of Publication 22.08.2024
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Year of Publication 22.08.2024
Patent
RECOMBINANT CD40 BINDING PROTEINS AND THEIR USE
SCHLEGEL, Anja Christina, RIGAMONTI, Nicolo, CALABRO, Valérie Perrine, DOMKE, Clara
Year of Publication 22.03.2023
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Year of Publication 22.03.2023
Patent
Recombinant CD40 binding proteins and their use
SCHLEGEL, Anja Christina, RIGAMONTI, Nicolo, CALABRO, Valérie Perrine, DOMKE, Clara
Year of Publication 15.12.2022
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Year of Publication 15.12.2022
Patent
A Multispecific Anti-CD40 DARPin Construct Induces Tumor-Selective CD40 Activation and Tumor Regression
Rigamonti, Nicolò, Veitonmäki, Niina, Domke, Clara, Barsin, Sophie, Jetzer, Sarah, Abdelmotaleb, Omar, Bessey, Ralph, Lekishvili, Tamara, Malvezzi, Francesca, Gachechiladze, Mariam, Behe, Martin, Levitsky, Victor, Trail, Pamela A
Published in Cancer immunology research (03.05.2022)
Published in Cancer immunology research (03.05.2022)
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