Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy
Baumann, Daniel, Hägele, Tanja, Mochayedi, Julian, Drebant, Jennifer, Vent, Caroline, Blobner, Sven, Noll, Julia Han, Nickel, Irena, Schumacher, Corinna, Boos, Sophie Luise, Daniel, Aline Sophie, Wendler, Susann, Volkmar, Michael, Strobel, Oliver, Offringa, Rienk
Published in Nature communications (01.05.2020)
Published in Nature communications (01.05.2020)
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Journal Article
Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines
Hartmann, Laura, Schröter, Philipp, Osen, Wolfram, Baumann, Daniel, Offringa, Rienk, Moustafa, Mahmoud, Will, Rainer, Debus, Jürgen, Brons, Stephan, Rieken, Stefan, Eichmüller, Stefan B.
Published in Scientific reports (09.12.2020)
Published in Scientific reports (09.12.2020)
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Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia
Kenter, Gemma G, Welters, Marij J.P, Valentijn, A. Rob P.M, Lowik, Margriet J.G, Berends-van der Meer, Dorien M.A, Vloon, Annelies P.G, Essahsah, Farah, Fathers, Lorraine M, Offringa, Rienk, Drijfhout, Jan Wouter, Wafelman, Amon R, Oostendorp, Jaap, Fleuren, Gert Jan, van der Burg, Sjoerd H, Melief, Cornelis J.M
Published in The New England journal of medicine (05.11.2009)
Published in The New England journal of medicine (05.11.2009)
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Journal Article
Radiation-induced alterations in immunogenicity of a murine pancreatic ductal adenocarcinoma cell line
Schröter, Philipp, Hartmann, Laura, Osen, Wolfram, Baumann, Daniel, Offringa, Rienk, Eisel, David, Debus, Jürgen, Eichmüller, Stefan B., Rieken, Stefan
Published in Scientific reports (20.01.2020)
Published in Scientific reports (20.01.2020)
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Journal Article
Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response
Karim, Rezaul, Tummers, Bart, Meyers, Craig, Biryukov, Jennifer L, Alam, Samina, Backendorf, Claude, Jha, Veena, Offringa, Rienk, van Ommen, Gert-Jan B, Melief, Cornelis J M, Guardavaccaro, Daniele, Boer, Judith M, van der Burg, Sjoerd H
Published in PLoS pathogens (01.05.2013)
Published in PLoS pathogens (01.05.2013)
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Journal Article
p38 MAPK signaling in M1 macrophages results in selective elimination of M2 macrophages by MEK inhibition
Baumann, Daniel, Drebant, Jennifer, Hägele, Tanja, Burger, Luisa, Serger, Clara, Lauenstein, Claudia, Dudys, Przemyslaw, Erdmann, Gerrit, Offringa, Rienk
Published in Journal for immunotherapy of cancer (01.07.2021)
Published in Journal for immunotherapy of cancer (01.07.2021)
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Journal Article
The enchanting canvas of CAR technology: Unveiling its wonders in non-neoplastic diseases
Shu, Jinhui, Xie, Wei, Chen, Zhaozhao, Offringa, Rienk, Hu, Yu, Mei, Heng
Published in Med (New York, N.Y. : Online) (14.06.2024)
Published in Med (New York, N.Y. : Online) (14.06.2024)
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Journal Article
Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes
Karim, Rezaul, Meyers, Craig, Backendorf, Claude, Ludigs, Kristina, Offringa, Rienk, van Ommen, Gert-Jan B, Melief, Cornelis J M, van der Burg, Sjoerd H, Boer, Judith M
Published in PloS one (14.03.2011)
Published in PloS one (14.03.2011)
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Journal Article
Induction of Tumor-Specific CD4+ and CD8+ T-Cell Immunity in Cervical Cancer Patients by a Human Papillomavirus Type 16 E6 and E7 Long Peptides Vaccine
WELTERS, Marij J. P, KENTER, Gemma G, JAN FLEUREN, Gert, OFFRINGA, Rienk, MELIEF, Cornelis J. M, VAN DER BURGS, Sjoerd H, PIERSMA, Sytse J, VLOON, Annelies P. G, LÖWIK, Margriet J. G, BERENDS-VAN DER MEER, Dorien M. A, DRIJFHOUT, Jan W, VALENTIJN, A. Rob P. M, WAFELMAN, Amon R, OOSTENDORP, Jaap
Published in Clinical cancer research (01.01.2008)
Published in Clinical cancer research (01.01.2008)
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CD8+ CTL Priming by Exact Peptide Epitopes in Incomplete Freund's Adjuvant Induces a Vanishing CTL Response, whereas Long Peptides Induce Sustained CTL Reactivity
Bijker, Martijn S, van den Eeden, Susan J. F, Franken, Kees L, Melief, Cornelis J. M, Offringa, Rienk, van der Burg, Sjoerd H
Published in The Journal of immunology (1950) (15.10.2007)
Published in The Journal of immunology (1950) (15.10.2007)
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Journal Article
Phase I Immunotherapeutic Trial with Long Peptides Spanning the E6 and E7 Sequences of High-Risk Human Papillomavirus 16 in End-Stage Cervical Cancer Patients Shows Low Toxicity and Robust Immunogenicity
Kenter, Gemma G, Welters, Marij J P, Valentijn, A Rob P M, Lowik, Margriet J G, Berends-van der Meer, Dorien M A, Vloon, Annelies P G, Drijfhout, Jan W, Wafelman, Amon R, Oostendorp, Jaap, Fleuren, Gert Jan, Offringa, Rienk, van der Burg, Sjoerd H, Melief, Cornelis J M
Published in Clinical cancer research (01.01.2008)
Published in Clinical cancer research (01.01.2008)
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Sensitization of Tumors for Attack by Virus-Specific CD8+ T-Cells Through Antibody-Mediated Delivery of Immunogenic T-Cell Epitopes
Sefrin, Julian P, Hillringhaus, Lars, Mundigl, Olaf, Mann, Karin, Ziegler-Landesberger, Doris, Seul, Heike, Tabares, Gloria, Knoblauch, Dominic, Leinenbach, Andreas, Friligou, Irene, Dziadek, Sebastian, Offringa, Rienk, Lifke, Valeria, Lifke, Alexander
Published in Frontiers in immunology (21.08.2019)
Published in Frontiers in immunology (21.08.2019)
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Journal Article
T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction
Pinkert, Jessica, Boehm, Hans-Henning, Trautwein, Mark, Doecke, Wolf-Dietrich, Wessel, Florian, Ge, Yingzi, Gutierrez, Eva Maria, Carretero, Rafael, Freiberg, Christoph, Gritzan, Uwe, Luetke-Eversloh, Merlin, Golfier, Sven, Von Ahsen, Oliver, Volpin, Valentina, Sorrentino, Antonio, Rathinasamy, Anchana, Xydia, Maria, Lohmayer, Robert, Sax, Julian, Nur-Menevse, Ayse, Hussein, Abir, Stamova, Slava, Beckmann, Georg, Glueck, Julian Marius, Schoenfeld, Dorian, Weiske, Joerg, Zopf, Dieter, Offringa, Rienk, Kreft, Bertolt, Beckhove, Philipp, Willuda, Joerg
Published in Oncoimmunology (01.01.2022)
Published in Oncoimmunology (01.01.2022)
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Journal Article
Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications
Cabo, Mariona, Offringa, Rienk, Zitvogel, Laurence, Kroemer, Guido, Muntasell, Aura, Galluzzi, Lorenzo
Published in Oncoimmunology (01.01.2017)
Published in Oncoimmunology (01.01.2017)
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Journal Article
Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation
Bijker, Martijn S, van den Eeden, Susan J.F, Franken, Kees L, Melief, Cornelis J.M, van der Burg, Sjoerd H, Offringa, Rienk
Published in European journal of immunology (01.04.2008)
Published in European journal of immunology (01.04.2008)
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Journal Article
Association of cervical cancer with the presence of CD4⁺ regulatory T cells specific for human papillomavirus antigens
van der Burg, Sjoerd H, Piersma, Sytse J, de Jong, Annemieke, van der Hulst, Jeanette M, Kwappenberg, Kitty M.C, van den Hende, Muriel, Welters, Marij J.P, Van Rood, Jon J, Fleuren, Gert Jan, Melief, Cornelis J.M, Kenter, Gemma G, Offringa, Rienk
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2007)
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Secretogranin II influences the assembly and function of MHC class I in melanoma
Steinfass, Tamara, Poelchen, Juliane, Sun, Qian, Mastrogiulio, Giovanni, Novak, Daniel, Vierthaler, Marlene, Pardo, Sandra, Federico, Aniello, Hüser, Laura, Hielscher, Thomas, Carretero, Rafael, Offringa, Rienk, Altevogt, Peter, Umansky, Viktor, Utikal, Jochen
Published in Experimental hematology & oncology (11.03.2023)
Published in Experimental hematology & oncology (11.03.2023)
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