Next-generation TCR sequencing - a tool to understand T-cell infiltration in human cancers
Poschke, Isabel, Flossdorf, Michael, Offringa, Rienk
Published in The Journal of pathology (01.12.2016)
Published in The Journal of pathology (01.12.2016)
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Cancer Immunotherapy Is More than a Numbers Game
Offringa, Rienk
Published in Science (American Association for the Advancement of Science) (06.10.2006)
Published in Science (American Association for the Advancement of Science) (06.10.2006)
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Safety of intravenous administration of a canarypox virus encoding the human wild-type p53 gene in colorectal cancer patients
Menon, Anand G, Kuppen, Peter J K, van der Burg, Sjoerd H, Offringa, Rienk, Bonnet, Marie Claude, Harinck, Bert I J, Tollenaar, Rob A E M, Redeker, Anke, Putter, Hein, Moingeon, Philippe, Morreau, Hans, Melief, Cornelis J M, van de Velde, Cornelis J H
Published in Cancer gene therapy (01.07.2003)
Published in Cancer gene therapy (01.07.2003)
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Protective Anti-Tumor Immunity Induced by Vaccination with Recombinant Adenoviruses Encoding Multiple Tumor-Associated Cytotoxic T Lymphocyte Epitopes in a String-of-Beads Fashion
Toes, R E, Hoeben, R C, van der Voort, E I, Ressing, M E, van der Eb, A J, Melief, C J, Offringa, R
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.1997)
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An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells
Wilson, Nicholas S., Yang, Becky, Yang, Annie, Loeser, Stefanie, Marsters, Scot, Lawrence, David, Li, Yun, Pitti, Robert, Totpal, Klara, Yee, Sharon, Ross, Sarajane, Vernes, Jean-Michel, Lu, Yanmei, Adams, Cam, Offringa, Rienk, Kelley, Bob, Hymowitz, Sarah, Daniel, Dylan, Meng, Gloria, Ashkenazi, Avi
Published in Cancer cell (18.01.2011)
Published in Cancer cell (18.01.2011)
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Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T‑Cell Immunity against Cancer
Mowat, Jeffrey, Carretero, Rafael, Leder, Gabriele, Aiguabella Font, Nuria, Neuhaus, Roland, Berndt, Sandra, Günther, Judith, Friberg, Anders, Schäfer, Martina, Briem, Hans, Raschke, Marian, Miyatake Ondozabal, Hideki, Buchmann, Bernd, Boemer, Ulf, Kreft, Bertolt, Hartung, Ingo V., Offringa, Rienk
Published in Journal of medicinal chemistry (10.10.2024)
Published in Journal of medicinal chemistry (10.10.2024)
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The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones
Poschke, Isabel C, Hassel, Jessica C, Rodriguez-Ehrenfried, Aaron, Lindner, Katharina A M, Heras-Murillo, Ignacio, Appel, Lena M, Lehmann, Johanna, Lövgren, Tanja, Wickström, Stina L, Lauenstein, Claudia, Roth, Jasmin, König, Anna-Katharina, Haanen, John B A G, van den Berg, Joost, Kiessling, Rolf, Bergmann, Frank, Flossdorf, Michael, Strobel, Oliver, Offringa, Rienk
Published in Clinical cancer research (15.08.2020)
Published in Clinical cancer research (15.08.2020)
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optiPRM: A Targeted Immunopeptidomics LC-MS Workflow With Ultra-High Sensitivity for the Detection of Mutation-Derived Tumor Neoepitopes From Limited Input Material
Salek, Mogjiborahman, Förster, Jonas D., Becker, Jonas P., Meyer, Marten, Charoentong, Pornpimol, Lyu, Yanhong, Lindner, Katharina, Lotsch, Catharina, Volkmar, Michael, Momburg, Frank, Poschke, Isabel, Fröhling, Stefan, Schmitz, Marc, Offringa, Rienk, Platten, Michael, Jäger, Dirk, Zörnig, Inka, Riemer, Angelika B.
Published in Molecular & cellular proteomics (01.09.2024)
Published in Molecular & cellular proteomics (01.09.2024)
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Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer
Meng, Zibo, Rodriguez Ehrenfried, Aaron, Tan, Chin Leng, Steffens, Laura K, Kehm, Hannes, Zens, Stefan, Lauenstein, Claudia, Paul, Alina, Schwab, Marius, Förster, Jonas D, Salek, Mogjiborahman, Riemer, Angelika B, Wu, Heshui, Eckert, Christoph, Leonhardt, Carl-Stephan, Strobel, Oliver, Volkmar, Michael, Poschke, Isabel, Offringa, Rienk
Published in Science translational medicine (15.11.2023)
Published in Science translational medicine (15.11.2023)
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Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells
Zurli, Vanessa, Montecchi, Tommaso, Heilig, Raphael, Poschke, Isabel, Volkmar, Michael, Wimmer, Giuliana, Boncompagni, Gioia, Turacchio, Gabriele, D'Elios, Mario Milco, Campoccia, Giuseppe, Resta, Nicoletta, Offringa, Rienk, Fischer, Roman, Acuto, Oreste, Baldari, Cosima Tatiana, Kabanova, Anna
Published in Science signaling (12.05.2020)
Published in Science signaling (12.05.2020)
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Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis
Gengenbacher, Nicolas, Singhal, Mahak, Mogler, Carolin, Hai, Ling, Milde, Laura, Pari, Ashik Ahmed Abdul, Besemfelder, Eva, Fricke, Claudine, Baumann, Daniel, Gehrs, Stephanie, Utikal, Jochen, Felcht, Moritz, Hu, Junhao, Schlesner, Matthias, Offringa, Rienk, Chintharlapalli, Sudhakar R, Augustin, Hellmut G
Published in Cancer discovery (01.02.2021)
Published in Cancer discovery (01.02.2021)
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Abstract LB-075: Increased T cell- activation resulting from the combination of the anti-CEACAM6 function-blocking antibody BAY 1834942 with checkpoint inhibitors targeting either PD-1/PD-L1 or TIM-3
Willuda, Joerg, Boehm, Hans-Henning, Pinkert, Jessica, Trautwein, Mark, Doecke, Wolf-Dietrich, Ahsen, Oliver von, Ziegelbauer, Karl, Offringa, Rienk, Kreft, Bertolt, Beckhove, Philipp
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma
Poschke, Isabel, Faryna, Marta, Bergmann, Frank, Flossdorf, Michael, Lauenstein, Claudia, Hermes, Jennifer, Hinz, Ulf, Hank, Thomas, Ehrenberg, Roland, Volkmar, Michael, Loewer, Martin, Glimm, Hanno, Hackert, Thilo, Sprick, Martin R., Höfer, Thomas, Trumpp, Andreas, Halama, Niels, Hassel, Jessica C., Strobel, Oliver, Büchler, Markus, Sahin, Ugur, Offringa, Rienk
Published in Oncoimmunology (01.12.2016)
Published in Oncoimmunology (01.12.2016)
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Abstract 1722: Enhancement of anti-tumor T-cell immunity by means of an oral small molecule targeting the intracellular immune checkpoint MAP4K1
Leder, Gabriele, Carretero, Rafael, Mowat, Jeffrey, Berndt, Sandra, Neuhaus, Roland, Font, Nuria Aiguabella, Boemer, Ulf, von Ahsen, Oliver, Eberspaecher, Uwe, Guenther, Judith, Grees, Mareike, Link, Corinna, Nicke, Barbara, Baumann, Daniel, Schaefer, Martina, Oezcan-Wahlbrink, Mine, Werbeck, Nicolas D., Hartung, Ingo, Kreft, Bertolt, Offringa, Rienk
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 3650: Trace'n'Seq: Assessing neuronal infiltration and its impact in pancreatic ductal carcinoma
Thiel, Vera, Renders, Simon, Panten, Jasper, Mochayedi, Julian, Offringa, Rienk, Sprick, Martin, Trumpp, Andreas
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer
PIERSMA, Sytse J, JORDANOVA, Ekaterina S, VAN DER BURG, Sjoerd H, VAN POELGEEST, Mariëtte I. E, KWAPPENBERG, Kitty M. C, VAN DER HULST, Jeanette M, DRIJFHOUT, Jan W, MELIEF, Cornelis J. M, KENTER, Gemma G, FLEUREN, Gert Jan, OFFRINGA, Rienk
Published in Cancer research (Chicago, Ill.) (2007)
Published in Cancer research (Chicago, Ill.) (2007)
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