A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with marfan and loeys-dietz syndrome
Rienhoff Jr, Hugh Young, Yeo, Chang-Yeol, Morissette, Rachel, Khrebtukova, Irina, Melnick, Jonathan, Luo, Shujun, Leng, Nan, Kim, Yeon-Jin, Schroth, Gary, Westwick, John, Vogel, Hannes, McDonnell, Nazli, Hall, Judith G., Whitman, Malcolm
Published in American journal of medical genetics. Part A (01.08.2013)
Published in American journal of medical genetics. Part A (01.08.2013)
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Journal Article
Cardiac R2 values are independent of the image analysis approach employed
Meloni, Antonella, Rienhoff Jr, Hugh Young, Jones, Amber, Pepe, Alessia, Lombardi, Massimo, Wood, John C.
Published in Magnetic resonance in medicine (01.08.2014)
Published in Magnetic resonance in medicine (01.08.2014)
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Journal Article
A phase 1 dose-escalation study: safety, tolerability, and pharmacokinetics of FBS0701, a novel oral iron chelator for the treatment of transfusional iron overload
Hugh Young Rienhoff, Jr, Vip Viprakasit, Lay Tay, Paul Harmatz, Elliott Vichinsky, Deborah Chirnomas, Janet L. Kwiatkowski, Amy Tapper, William Kramer, John B. Porter, Ellis J. Neufeld
Published in Haematologica (Roma) (01.04.2011)
Published in Haematologica (Roma) (01.04.2011)
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Journal Article
KDM1A KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE
CELATKA CASSANDRA, TAPPER AMY E, MCCALL JOHN M, CLARE MICHAEL, RIENHOFF HUGH YOUNG JR
Year of Publication 16.10.2017
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Year of Publication 16.10.2017
Patent
MSC Reprogramming and Aberrant Inflammatory Signaling in Myelofibrosis: Insights from Single-Cell RNA-Sequencing of Trephine Bone Marrow Cells
Basma, Naseer J, Strickson, Alexia J, Gurashi, Kristian, Kleppe, Maria, Rienhoff Jr, Hugh Young, Somervaille, Tim CP
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Mutational Analysis of the Genome Stability Factor BOD1L1 in Myeloproliferative Neoplasm
Higgs, Martin R, Browne, Sofia, Collinson, Ryan, Fuller, Kathy, Erber, Wendy N., Kleppe, Maria, Sirnosian, Ben, Natsoulis, Georges, Guo, Belinda, Rienhoff Jr, Hugh Young
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Phase 2 Study to Assess the Safety and Efficacy of Bomedemstat (MK3543) in Combination with Ruxolitinib in Patients with Myelofibrosis
Gill, Harinder, Au, Lester, Leung, Garret Man Kit, Tsai, Dorothy, Yim, Rita, Chin, Lynn, Li, Vivian, Lee, Paul, Leung, Rock Yuk Yan, Lee, Elaine, Rienhoff Jr, Hugh Young, Kwong, Yok Lam
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
LSD1 Inhibition Enhances Antigen Presentation and Co-Stimulation in AML to Promote T Cell-Mediated Anti-Leukemia Immune Responses
Yan, Yu, Singh, Kanwaldeep, Hartung, Emily, Lee, Brendan, Prabagaran, Pradhariny, Khalaf, Dina, Garcia-Horton, Alejandro, Leber, Brian, Walker, Irwin, Lepic, Kylie L., Kleppe, Maria, Rienhoff Jr, Hugh Young Young, Bramson, Jonathan, Berg, Tobias
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Bomedemstat (IMG-7289), an LSD1 Inhibitor, Manages the Signs and Symptoms of Essential Thrombocythemia (ET) While Reducing the Burden of Cells Homozygous for Driver Mutations
Goethert, Joachim R., Gill, Harinder, Palandri, Francesca, Ross, David M., Cochrane, Tara, Larsen, Stephen R., Halpern, Anna B., Shortt, Jake, Rossetti, James M., Liang, James, Marchetti, Monia, Wilson, Andrew J., Innes, Andrew, Hanna, Merit, Stevenson, William S., Vannucchi, Alessandro M., Kleppe, Maria, Natsoulis, Georges, Harrison, Claire N, Rienhoff Jr, Hugh Young
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Genomewide Association Studies and Assessment of Risk of Disease
Pandey, Janardan P, Rienhoff, Hugh Young, Manolio, Teri A
Published in The New England journal of medicine (18.11.2010)
Published in The New England journal of medicine (18.11.2010)
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Journal Article
A phase 2 study of the safety, tolerability, and pharmacodynamics of FBS0701, a novel oral iron chelator, in transfusional iron overload
Neufeld, Ellis J., Galanello, Renzo, Viprakasit, Vip, Aydinok, Yesim, Piga, Antonio, Harmatz, Paul, Forni, Gian Luca, Shah, Farrukh T., Grace, Rachael F., Porter, John B., Wood, John C., Peppe, Jennifer, Jones, Amber, Rienhoff, Hugh Young
Published in Blood (05.04.2012)
Published in Blood (05.04.2012)
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Journal Article
Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model
Ferrer, Patricia, Tripathi, Abhai K, Clark, Martha A, Hand, Carla Cerami, Rienhoff, Jr, Hugh Young, Sullivan, Jr, David J
Published in PloS one (21.05.2012)
Published in PloS one (21.05.2012)
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Journal Article
Two monogenic disorders masquerading as one: severe congenital neutropenia with monocytosis and non-syndromic sensorineural hearing loss
Venugopal, Parvathy, Gagliardi, Lucia, Forsyth, Cecily, Feng, Jinghua, Phillips, Kerry, Babic, Milena, Poplawski, Nicola K, Rienhoff, Jr, Hugh Young, Schreiber, Andreas W, Hahn, Christopher N, Brown, Anna L, Scott, Hamish S
Published in BMC medical genetics (17.02.2020)
Published in BMC medical genetics (17.02.2020)
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Journal Article