Optimization of Thienopyrrole‐Based Finger‐Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase
Martin Hernando, Jose Ignacio, Ontoria, Jesus Maria, Malancona, Savina, Attenni, Barbara, Fiore, Fabrizio, Bonelli, Fabio, Koch, Uwe, Di Marco, Stefania, Colarusso, Stefania, Ponzi, Simona, Gennari, Nadia, Vignetti, Sue Ellen, del Rosario Rico Ferreira, Maria, Habermann, Jörg, Rowley, Michael, Narjes, Frank
Published in ChemMedChem (05.10.2009)
Published in ChemMedChem (05.10.2009)
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Journal Article
Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells
Cash, Timothy P., Alcalá, Sonia, Rico-Ferreira, María del Rosario, Hernández-Encinas, Elena, García, Jennifer, Albarrán, María Isabel, Valle, Sandra, Muñoz, Javier, Martínez-González, Sonia, Blanco-Aparicio, Carmen, Pastor, Joaquín, Serrano, Manuel, Sainz, Bruno
Published in Cancers (04.07.2020)
Published in Cancers (04.07.2020)
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Journal Article
Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones
Gardelli, Cristina, Nizi, Emanuela, Muraglia, Ester, Crescenzi, Benedetta, Ferrara, Marco, Orvieto, Federica, Pace, Paola, Pescatore, Giovanna, Poma, Marco, Rico Ferreira, Maria del Rosario, Scarpelli, Rita, Homnick, Carl F, Ikemoto, Norihiro, Alfieri, Anna, Verdirame, Maria, Bonelli, Fabio, Gonzalez Paz, Odalys, Taliani, Marina, Monteagudo, Edith, Pesci, Silvia, Laufer, Ralph, Felock, Peter, Stillmock, Kara A, Hazuda, Daria, Rowley, Michael, Summa, Vincenzo
Published in Journal of medicinal chemistry (04.10.2007)
Published in Journal of medicinal chemistry (04.10.2007)
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Journal Article
Development of a Scalable Chiral Synthesis of MK-3281, an Inhibitor of the Hepatitis C Virus NS5B Polymerase
Colarusso, Stefania, Conte, Immacolata, Di Filippo, Marcello, Ercolani, Caterina, Mackay, Angela C., Palumbi, Maria Cecilia, Ferreira, Maria del Rosario Rico, Stansfield, Ian, Zaramella, Simone, Narjes, Frank, Habermann, Joerg
Published in Synlett (01.07.2011)
Published in Synlett (01.07.2011)
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Journal Article
Discovery of (7R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase
Narjes, Frank, Crescenzi, Benedetta, Ferrara, Marco, Habermann, Jörg, Colarusso, Stefania, del Rosario Rico Ferreira, Maria, Stansfield, Ian, Mackay, Angela Claire, Conte, Immacolata, Ercolani, Caterina, Zaramella, Simone, Palumbi, Maria-Cecilia, Meuleman, Philip, Leroux-Roels, Geert, Giuliano, Claudio, Fiore, Fabrizio, Di Marco, Stefania, Baiocco, Paola, Koch, Uwe, Migliaccio, Giovanni, Altamura, Sergio, Laufer, Ralph, De Francesco, Raffaele, Rowley, Michael
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
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Journal Article
The aldol–annulation–fragmentation strategy toward the taxoid diterpene framework revisited. Instructive failures in the chemistry of medium ring containing systems
Hamon, Sylvain, del Rosario Rico Ferreira, María, Quílez del Moral, José, Martín Hernando, José I., Candela Lena, José I., Birlirakis, Nicolas, Toupet, Loı¨c, Arseniyadis, Siméon
Published in Tetrahedron: asymmetry (03.10.2005)
Published in Tetrahedron: asymmetry (03.10.2005)
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Journal Article
Synthesis of Indolo[2,1-a][2]benzazepine and Indolo[2,1-a][2]-benzazocine
Ponzi, Simona, Habermann, Joerg, Ferreira, Maria del Rosario Rico, Narjes, Frank
Published in Synlett (03.06.2009)
Published in Synlett (03.06.2009)
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Journal Article
Stereoselective synthesis of an A-seco-taxoid subunit using the Aldol-annelation-fragmentation strategy
Arseniyadis, Siméon, del Rosario Rico Ferreira, María, Quílez del Moral, José, Ignacio Martín Hernando, José, Potier, Pierre, Toupet, Loïc
Published in Tetrahedron letters (01.10.1998)
Published in Tetrahedron letters (01.10.1998)
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Journal Article
Modified steroids: Pb(OAc) 4 mediated one-pot multistage transformations of steroidal unsaturated 1,2-diols
del Rosario Rico Ferreira, Maria, Martı́n Hernando, José Ignacio, Candela Lena, José Ignacio, Quı́lez del Moral, José, Arseniyadis, Siméon
Published in Tetrahedron: asymmetry (23.04.1999)
Published in Tetrahedron: asymmetry (23.04.1999)
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Journal Article
Advanced taxoids from Hajos-Parrish ketone and isophorone by the transmetallation (C11-C12)-aldol (C1-C2) approach
Ferreira, MDR, Hernando, JIM, Lena, JIC, Birlirakis, N, Arseniyadis, S
Published in Synlett (01.01.2000)
Published in Synlett (01.01.2000)
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Journal Article
A rapid entry into major groups of taxoids
Ignacio Martı́n Hernando, José, del Rosario Rico Ferreira, Maria, Ignacio Candela Lena, José, Birlirakis, Nicolas, Arseniyadis, Siméon
Published in Tetrahedron letters (05.02.2000)
Published in Tetrahedron letters (05.02.2000)
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Journal Article
Taxoid C-ring building blocks from Hajos–Parrish ketone. Practical synthesis of an enantiomerically pure taxoid ABC ring system
Martı́n Hernando, José Ignacio, Quı́lez del Moral, José, Rico Ferreira, Maria del Rosario, Candela Lena, José Ignacio, Arseniyadis, Siméon
Published in Tetrahedron: asymmetry (26.02.1999)
Published in Tetrahedron: asymmetry (26.02.1999)
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Journal Article
Discovery of (7 R )-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6 H -indolo[1,2- e ][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase
Narjes, Frank, Crescenzi, Benedetta, Ferrara, Marco, Habermann, Jörg, Colarusso, Stefania, del Rosario Rico Ferreira, Maria, Stansfield, Ian, Mackay, Angela Claire, Conte, Immacolata, Ercolani, Caterina, Zaramella, Simone, Palumbi, Maria-Cecilia, Meuleman, Philip, Leroux-Roels, Geert, Giuliano, Claudio, Fiore, Fabrizio, Di Marco, Stefania, Baiocco, Paola, Koch, Uwe, Migliaccio, Giovanni, Altamura, Sergio, Laufer, Ralph, De Francesco, Raffaele, Rowley, Michael
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
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Journal Article
Studies towards the total synthesis of taxoids: a rapid entry into bicyclo[6.4.0]dodecane ring system. Part 1
Arseniyadis, Siméon, Rico Ferreira, Marı́a del Rosario, Quı́lez del Moral, José, Martı́n Hernando, José Ignacio, Potier, Pierre, Toupet, Loı̈c
Published in Tetrahedron: asymmetry (27.11.1998)
Published in Tetrahedron: asymmetry (27.11.1998)
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Journal Article
An expedient synthesis of a conveniently functionalized optically homogeneous taxoid ABC ring system
Arseniyadis, Siméon, Martín Hernando, JoséIgnacio, Quílez del Moral, José, del Rosario Rico Ferreira, Maria, Birlirakis, Nicolas, Potier, Pierre
Published in Tetrahedron letters (03.12.1998)
Published in Tetrahedron letters (03.12.1998)
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Journal Article
Studies culminating in the total synthesis and determination of the absolute configuration of (-)-saudin: Organic Synthesis-2011: Perspective, Journeys, and Accounts
BOECKMAN, Robert K, DEL ROSARIO FERREIRA, Maria Rico, MITCHELL, Lorna H, SHAO, Pengcheng, NEEB, Michael J, YUE FANG
Published in Tetrahedron (2011)
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Published in Tetrahedron (2011)
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