Identification of Clinical Candidate M2698, a Dual p70S6K and Akt Inhibitor, for Treatment of PAM Pathway-Altered Cancers
DeSelm, Lizbeth, Huck, Bayard, Lan, Ruoxi, Neagu, Constantin, Potnick, Justin, Xiao, Yufang, Chen, Xiaoling, Jones, Reinaldo, Richardson, Thomas E, Heasley, Brian H, Haxell, Thomas, Moore, Joseph, Tian, Hui, Georgi, Katrin, Rohdich, Felix, Sutton, Amanda, Johnson, Theresa, Mochalkin, Igor, Jackson, Jennifer, Lin, Jing, Crowley, Lindsey, Machl, Andreas, Clark, Anderson, Wilker, Erik, Sherer, Brian, Goutopoulos, Andreas
Published in Journal of medicinal chemistry (14.10.2021)
Published in Journal of medicinal chemistry (14.10.2021)
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Synthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) – An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity
Brockway, Anthony J., Volkov, Oleg A., Cosner, Casey C., MacMillan, Karen S., Wring, Stephen A., Richardson, Thomas E., Peel, Michael, Phillips, Margaret A., De Brabander, Jef K.
Published in Bioorganic & medicinal chemistry (15.10.2017)
Published in Bioorganic & medicinal chemistry (15.10.2017)
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Discovery of substituted benzamides as follicle stimulating hormone receptor allosteric modulators
Yu, Henry N., Richardson, Thomas E., Nataraja, Selva, Fischer, David J., Sriraman, Venkataraman, Jiang, Xuliang, Bharathi, Pandi, Foglesong, Robert J., Haxell, Thomas F.N., Heasley, Brian H., Jenks, Mathew, Li, Jane, Dugas, Melanie S., Collis, Regina, Tian, Hui, Palmer, Stephen, Goutopoulos, Andreas
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
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Identification of Trypanosoma brucei AdoMetDC Inhibitors Using a High-Throughput Mass Spectrometry-Based Assay
Volkov, Oleg A, Cosner, Casey C, Brockway, Anthony J, Kramer, Martin, Booker, Michael, Zhong, Shihua, Ketcherside, Ariel, Wei, Shuguang, Longgood, Jamie, McCoy, Melissa, Richardson, Thomas E, Wring, Stephen A, Peel, Michael, Klinger, Jeffrey D, Posner, Bruce A, De Brabander, Jef K, Phillips, Margaret A
Published in ACS infectious diseases (14.07.2017)
Published in ACS infectious diseases (14.07.2017)
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Structural changes caused by site-directed mutagenesis of tyrosine-98 in Desulfovibrio vulgaris flavodoxin delineated by 1H and 15N NMR spectroscopy: implications for redox potential modulation
Stockman, Brian J, Richardson, Thomas E, Swenson, Richard P
Published in Biochemistry (Easton) (01.12.1994)
Published in Biochemistry (Easton) (01.12.1994)
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NOVEL AZAHETEROCYCLIC COMPOUNDS
LAN RUOXI, HUCK BAYARD R, SUTTON AMANDA E, BRUGGER NADIA, RICHARDSON THOMAS E, VANDEVEER HAROLD GEORGE, POTNICK JUSTIN
Year of Publication 08.06.2012
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Year of Publication 08.06.2012
Patent
NOVEL AMINO AZAHETEROCYCLIC CARBOXAMIDES
PERREY DAVID, LIU BUJALSKI LESLEY, STIEBER FRANK, GOUTOPOULOS ANDREAS, JONES REINALDO C, HODOUS BRIAN L, KARRA SRINIVASA R, QIU HUI, LAN RUOXI, HEASLEY BRIAN, HUCK BAYARD R, SUTTON AMANDA E, RICHARDSON THOMAS E, XIAO YUFANG, VANDEVEER HAROLD GEORGE, CHEN XIAOLING
Year of Publication 03.11.2011
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Year of Publication 03.11.2011
Patent