Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy
Singh, Sheo B, Jayasuriya, Hiranthi, Ondeyka, John G, Herath, Kithsiri B, Zhang, Chaowei, Zink, Deborah L, Tsou, Nancy N, Ball, Richard G, Basilio, Angela, Genilloud, Olga, Diez, Maria Teresa, Vicente, Francisca, Pelaez, Fernando, Young, Katherine, Wang, Jun
Published in Journal of the American Chemical Society (13.09.2006)
Published in Journal of the American Chemical Society (13.09.2006)
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Conformational analysis of N,N-disubstituted-1,4-diazepane orexin receptor antagonists and implications for receptor binding
Cox, Christopher D., McGaughey, Georgia B., Bogusky, Michael J., Whitman, David B., Ball, Richard G., Winrow, Christopher J., Renger, John J., Coleman, Paul J.
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
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Journal Article
Synthesis of Antifungal Glucan Synthase Inhibitors from Enfumafungin
Zhong, Yong-Li, Gauthier, Donald R, Shi, Yao-Jun, McLaughlin, Mark, Chung, John Y. L, Dagneau, Philippe, Marcune, Benjamin, Krska, Shane W, Ball, Richard G, Reamer, Robert A, Yasuda, Nobuyoshi
Published in Journal of organic chemistry (06.04.2012)
Published in Journal of organic chemistry (06.04.2012)
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Journal Article
Layered Structure and Swelling Behavior of a Multiple Hydrate-Forming Pharmaceutical Compound
Kiang, Y.-H, Xu, Wei, Stephens, Peter W, Ball, Richard G, Yasuda, Nobuyoshi
Published in Crystal growth & design (01.04.2009)
Published in Crystal growth & design (01.04.2009)
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Journal Article
Fragment-based lead discovery of a novel class of small molecule antagonists of neuropeptide B/W receptor subtype 1 (GPR7)
Moningka, Remond, Romero, F. Anthony, Hastings, Nicholas B., Guo, Zhiqiang, Wang, Ming, Di Salvo, Jerry, Li, Ying, Trusca, Dorina, Deng, Qiaoling, Tong, Vincent, Terebetski, Jenna L., Ball, Richard G., Ujjainwalla, Feroze
Published in Bioorganic & medicinal chemistry letters (01.12.2020)
Published in Bioorganic & medicinal chemistry letters (01.12.2020)
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Journal Article
Cyclopentane-based human NK1 antagonists. Part 2: Development of potent, orally active, water-soluble derivatives
Meurer, Laura C., Finke, Paul E., Owens, Karen A., Tsou, Nancy N., Ball, Richard G., Mills, Sander G., MacCoss, Malcolm, Sadowski, Sharon, Cascieri, Margaret A., Tsao, Kwei-Lan, Chicchi, Gary G., Egger, Linda A., Luell, Silvi, Metzger, Joseph M., MacIntyre, D. Euan, Rupniak, Nadia M.J., Williams, Angela R., Hargreaves, Richard J.
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
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The discovery of potent, selective, and orally bioavailable hNK1 antagonists derived from pyrrolidine
LIN, Peter, LEHUA CHANG, KURTZ, Marc M, TSAO, Kwei-Lan C, WHEELDON, Alan, CARLSON, Emma J, ENG, Waisi, BURNS, H. Donald, HARGREAVES, Richard J, MILLS, Sander G, DEVITA, Robert J, YOUNG, Jonathan R, EID, Ronsar, XINCHUN TONG, SONG ZHENG, BALL, Richard G, TSOU, Nancy N, CHICCHI, Gary G
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
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Journal Article
Nodulisporic Acid A, a Novel and Potent Insecticide from a Nodulisporium Sp. Isolation, Structure Determination, and Chemical Transformations
Ondeyka, John G, Helms, Gregory L, Hensens, Otto D, Goetz, Michael A, Zink, Deborah L, Tsipouras, Athanasios, Shoop, Wesley L, Slayton, Lyndia, Dombrowski, Anne W, Polishook, Jon D, Ostlind, Dan A, Tsou, Nancy N, Ball, Richard G, Singh, Sheo B
Published in Journal of the American Chemical Society (24.09.1997)
Published in Journal of the American Chemical Society (24.09.1997)
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Discovery of [(2R,5R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties
Coleman, Paul J., Schreier, John D., Cox, Christopher D., Breslin, Michael J., Whitman, David B., Bogusky, Michael J., McGaughey, Georgia B., Bednar, Rodney A., Lemaire, Wei, Doran, Scott M., Fox, Steven V., Garson, Susan L., Gotter, Anthony L., Harrell, C. Meacham, Reiss, Duane R., Cabalu, Tamara D., Cui, Donghui, Prueksaritanont, Thomayant, Stevens, Joanne, Tannenbaum, Pamela L., Ball, Richard G., Stellabott, Joyce, Young, Steven D., Hartman, George D., Winrow, Christopher J., Renger, John J.
Published in ChemMedChem (05.03.2012)
Published in ChemMedChem (05.03.2012)
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Stereoselective Addition of 2‑Phenyloxazol-4-yl Trifluoromethanesulfonate to N‑Sulfinyl Imines: Application to the Synthesis of the HCV Protease Inhibitor Boceprevir
Morris, William J, Muppalla, Kiran K, Cowden, Cameron, Ball, Richard G
Published in Journal of organic chemistry (18.01.2013)
Published in Journal of organic chemistry (18.01.2013)
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Journal Article
Chemistry of platensimycin
Singh, Sheo B., Herath, Kithsiri B., Wang, Jun, Tsou, Nancy, Ball, Richard G.
Published in Tetrahedron letters (30.07.2007)
Published in Tetrahedron letters (30.07.2007)
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Journal Article
Isolation and Structure Elucidation of Parnafungins, Antifungal Natural Products that Inhibit mRNA Polyadenylation
Parish, Craig A, Smith, Scott K, Calati, Kathleen, Zink, Deborah, Wilson, Kenneth, Roemer, Terry, Jiang, Bo, Xu, Deming, Bills, Gerald, Platas, Gonzalo, Peláez, Fernando, Díez, Maria Teresa, Tsou, Nancy, McKeown, Arlene E, Ball, Richard G, Powles, Mary Ann, Yeung, Lai, Liberator, Paul, Harris, Guy
Published in Journal of the American Chemical Society (04.06.2008)
Published in Journal of the American Chemical Society (04.06.2008)
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Development of a pharmaceutical cocrystal of a monophosphate salt with phosphoric acid
Chen, Alex M, Ellison, Martha E, Peresypkin, Andrey, Wenslow, Robert M, Variankaval, Narayan, Savarin, Cecile G, Natishan, Theresa K, Mathre, David J, Dormer, Peter G, Euler, Danielle H, Ball, Richard G, Ye, Zhixiong, Wang, Yaling, Santos, Ivan
Published in Chemical communications (Cambridge, England) (01.01.2007)
Published in Chemical communications (Cambridge, England) (01.01.2007)
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Journal Article
Diastereoselective Friedel−Crafts Alkylation of Indoles with Chiral α-Phenyl Benzylic Cations. Asymmetric Synthesis of Anti-1,1,2-Triarylalkanes
Chung, John Y. L, Mancheno, Danny, Dormer, Peter G, Variankaval, Narayan, Ball, Richard G, Tsou, Nancy N
Published in Organic letters (17.07.2008)
Published in Organic letters (17.07.2008)
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Journal Article
Structure−Activity Relationship of Heterobase-Modified 2‘-C-Methyl Ribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication
Eldrup, Anne B, Prhavc, Marija, Brooks, Jennifer, Bhat, Balkrishen, Prakash, Thazha P, Song, Quanlai, Bera, Sanjib, Bhat, Neelima, Dande, Prasad, Cook, P. Dan, Bennett, C. Frank, Carroll, Steven S, Ball, Richard G, Bosserman, Michele, Burlein, Christine, Colwell, Lawrence F, Fay, John F, Flores, Osvaldo A, Getty, Krista, LaFemina, Robert L, Leone, Joseph, MacCoss, Malcolm, McMasters, Daniel R, Tomassini, Joanne E, von Langen, Derek, Wolanski, Bohdan, Olsen, David B
Published in Journal of medicinal chemistry (07.10.2004)
Published in Journal of medicinal chemistry (07.10.2004)
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Journal Article
Total Synthesis and Determination of the Absolute Configuration of Epibatidine
Fletcher, Stephen R, Baker, Raymond, Chambers, Mark S, Herbert, Richard H, Hobbs, Sarah C, Thomas, Steven R, Verrier, Hugh M, Watt, Alan P, Ball, Richard G
Published in Journal of organic chemistry (01.04.1994)
Published in Journal of organic chemistry (01.04.1994)
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Journal Article
Asymmetric Synthesis of a Glucagon Receptor Antagonist via Friedel–Crafts Alkylation of Indole with Chiral α‑Phenyl Benzyl Cation
Chung, John Y. L, Steinhuebel, Dietrich, Krska, Shane W, Hartner, Fred W, Cai, Chaoxian, Rosen, Jonathan, Mancheno, Danny E, Pei, Tao, DiMichele, Lisa, Ball, Richard G, Chen, Cheng-yi, Tan, Lushi, Alorati, Antony D, Brewer, Sarah E, Scott, Jeremy P
Published in Organic process research & development (16.11.2012)
Published in Organic process research & development (16.11.2012)
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