Modulation of [gamma]-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice
Rogers, Kathryn, Felsenstein, Kevin M, Hrdlicka, Lori, Tu, Zhiming, Albayya, Faris, Lee, Winnie, Hopp, Sarah, Miller, Mary-Jo, Spaulding, Darcie, Yang, Zhiyong, Hodgdon, Hilliary, Nolan, Scott, Wen, Melody, Costa, Don, Blain, Jean-Francois, Freeman, Emily, De Strooper, Bart, Vulsteke, Veerle, Scrocchi, Louise, Zetterberg, Henrik, Portelius, Erik, Hutter-Paier, Birgit, Havas, Daniel, Ahlijanian, Michael, Flood, Dorothy, Leventhal, Liza, Shapiro, Gideon, Patzke, Holger, Chesworth, Richard, Koenig, Gerhard
Published in Molecular neurodegeneration (01.01.2012)
Published in Molecular neurodegeneration (01.01.2012)
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Estrogen receptor β selective ligands: Discovery and SAR of novel heterocyclic ligands
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Published in Bioorganic & medicinal chemistry letters (15.12.2005)
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
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Pharmacokinetic and pharmacodynamic analysis of the gamma-secretase modulator (GSM) EVP-0015962
Felsenstein, Kevin M, Spaulding, Darcie, Yang, Zhiyong, Hodgdon, Hilliary, Costa, Don, Nolan, Scott, Wen, Melody, Lee, Winnie, Hrdlicka, Lori, Catana, Florentina, Albayya, Faris, Tu, Zhiming, Patzke, Holger, Chesworth, Richard, Shapiro, Gideon, Zaninovic, Irena, Ahlijanian, Michael, Koenig, Gerhard, Rogers, Kathryn
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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P3‐291: Putative gamma secretase modulators lower Aβ 42 in multiple in vitro and in vivo models
Rogers, Kathryn, Chesworth, Richard, Felsenstein, Kevin, Shapiro, Gideon, Albayya, Faris, Tu, Zhiming, Spaulding, Darcie, Catana, Florentina, Hrdlicka, Lori, Nolan, Scott, Wen, Melody, Yang, Zhiyong, Vulsteke, Veerle, Patzke, Holger, Koenig, Gerhard, DeStrooper, Bart, Ahlijanian, Michael
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
Putative gamma secretase modulators lower Aβ42 in multiple in vitro and in vivo models
Rogers, Kathryn, Chesworth, Richard, Felsenstein, Kevin, Shapiro, Gideon, Albayya, Faris, Tu, Zhiming, Spaulding, Darcie, Catana, Florentina, Hrdlicka, Lori, Nolan, Scott, Wen, Melody, Yang, Zhiyong, Vulsteke, Veerle, Patzke, Holger, Koenig, Gerhard, DeStrooper, Bart, Ahlijanian, Michael
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
P3‐291: Putative gamma secretase modulators lower Aβ42 in multiple in vitro and in vivo models
Rogers, Kathryn, Chesworth, Richard, Felsenstein, Kevin, Shapiro, Gideon, Albayya, Faris, Tu, Zhiming, Spaulding, Darcie, Catana, Florentina, Hrdlicka, Lori, Nolan, Scott, Wen, Melody, Yang, Zhiyong, Vulsteke, Veerle, Patzke, Holger, Koenig, Gerhard, DeStrooper, Bart, Ahlijanian, Michael
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Arginine methyltransferase inhibitors and uses thereof
Shapiro, Gideon, Chesworth, Richard, Swinger, Kerren Kalai, Mitchell, Lorna Helen
Year of Publication 29.11.2022
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Year of Publication 29.11.2022
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Tetrahydroisoquinolines as subtype selective estrogen agonists/antagonists
Chesworth, Richard, Zawistoski, Michael P., Lefker, Bruce A., Cameron, Kimberly O., Day, Robert F., Mangano, F.Michael, Rosati, Robert L., Colella, Stacy, Petersen, Donna N., Brault, Amy, Lu, Bihong, Pan, Lydia C., Perry, Pia, Ng, Oicheng, Castleberry, Tessa A., Owen, Thomas A., Brown, Thomas A., Thompson, David D., DaSilva-Jardine, Paul
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
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A microglia clonal inflammatory disorder in Alzheimer's Disease
Vicario, Rocio, Fragkogianni, Stamatina, Weber, Leslie, Lazarov, Tomi, Hu, Yang, Hayashi, Samantha Y, Craddock, Barbara P, Socci, Nicholas D, Alberdi, Araitz, Baako, Ann, Ay, Oyku, Ogishi, Masato, Lopez-Rodrigo, Estibaliz, Kappagantula, Rajya, Viale, Agnes, Iacobuzio-Donahue, Christine A, Zhou, Ting, Ransohoff, Richard M, Chesworth, Richard, Abdel-Wahab, Omar, Boisson, Bertrand, Elemento, Olivier, Casanova, Jean-Laurent, Miller, W Todd, Geissmann, Frederic
Published in bioRxiv (03.08.2024)
Published in bioRxiv (03.08.2024)
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CARM1 INHIBITORS AND USES THEREOF
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Year of Publication 28.12.2023
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Year of Publication 28.12.2023
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Babine, Robert E, Shapiro, Gideon, Chesworth, Richard, Moradei, Oscar Miguel, Jin, Lei
Year of Publication 05.12.2023
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Year of Publication 05.12.2023
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PRMT5 INHIBITORS AND USES THEREOF
CHESWORTH, Richard, JIN, Lei, BORIACK-SJODIN, Paula Ann, DUNCAN, Kenneth W, MUNCHHOF, Michael John
Year of Publication 27.09.2023
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Year of Publication 27.09.2023
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CARM1 INHIBITORS AND USES THEREOF
Babine, Robert E, Shapiro, Gideon, Chesworth, Richard, Moradei, Oscar Miguel, Jin, Lei
Year of Publication 07.09.2023
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Year of Publication 07.09.2023
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CARM1 INHIBITORS AND USES THEREOF
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Year of Publication 29.08.2023
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Year of Publication 29.08.2023
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CHESWORTH, Richard, JIN, Lei, BORIACK-SJODIN, Paula Ann, DUNCAN, Kenneth W, MUNCHHOF, Michael John
Year of Publication 02.08.2023
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Year of Publication 02.08.2023
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ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF
SHAPIRO, GIDEON, SWINGER, KERREN KALAI, MITCHELL, LORNA HELEN, CHESWORTH, RICHARD
Year of Publication 31.08.2021
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Year of Publication 31.08.2021
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