Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution
Thirumangalathu, Renuka, Krishnan, Sampathkumar, Ricci, Margaret Speed, Brems, David N., Randolph, Theodore W., Carpenter, John F.
Published in Journal of pharmaceutical sciences (01.09.2009)
Published in Journal of pharmaceutical sciences (01.09.2009)
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Journal Article
Elucidation of Degradants in Acidic Peak of Cation Exchange Chromatography in an IgG1 Monoclonal Antibody Formed on Long-Term Storage in a Liquid Formulation
Gandhi, Sejal, Ren, Da, Xiao, Gang, Bondarenko, Pavel, Sloey, Christopher, Ricci, Margaret Speed, Krishnan, Sampathkumar
Published in Pharmaceutical research (01.01.2012)
Published in Pharmaceutical research (01.01.2012)
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Journal Article
Optimization of a reversed-phase high-performance liquid chromatography/mass spectrometry method for characterizing recombinant antibody heterogeneity and stability
Dillon, Thomas M., Bondarenko, Pavel V., Rehder, Douglas S., Pipes, Gary D., Kleemann, Gerd R., Ricci, Margaret Speed
Published in Journal of Chromatography A (07.07.2006)
Published in Journal of Chromatography A (07.07.2006)
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Journal Article
Conference Proceeding
Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 Subclass
Dillon, Thomas M., Ricci, Margaret Speed, Vezina, Chris, Flynn, Gregory C., Liu, Yaoqing Diana, Rehder, Douglas S., Plant, Matthew, Henkle, Brad, Li, Yu, Deechongkit, Songpon, Varnum, Brian, Wypych, Jette, Balland, Alain, Bondarenko, Pavel V.
Published in The Journal of biological chemistry (06.06.2008)
Published in The Journal of biological chemistry (06.06.2008)
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Journal Article
Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms
Wypych, Jette, Li, Ming, Guo, Amy, Zhang, Zhongqi, Martinez, Theresa, Allen, Martin J., Fodor, Szilan, Kelner, Drew N., Flynn, Gregory C., Liu, Yaoqing Diana, Bondarenko, Pavel V., Ricci, Margaret Speed, Dillon, Thomas M., Balland, Alain
Published in The Journal of biological chemistry (06.06.2008)
Published in The Journal of biological chemistry (06.06.2008)
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Journal Article
Development of an analytical reversed-phase high-performance liquid chromatography–electrospray ionization mass spectrometry method for characterization of recombinant antibodies
Dillon, Thomas M., Bondarenko, Pavel V., Speed Ricci, Margaret
Published in Journal of Chromatography A (22.10.2004)
Published in Journal of Chromatography A (22.10.2004)
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Journal Article
Effects of excipients on the hydrogen peroxide-induced oxidation of methionine residues in granulocyte colony-stimulating factor
Yin, Jin, Chu, Jhih-Wei, Ricci, Margaret Speed, Brems, David N, Wang, Daniel I C, Trout, Bernhardt L
Published in Pharmaceutical research (01.01.2005)
Published in Pharmaceutical research (01.01.2005)
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Journal Article
Effects of antioxidants on the hydrogen peroxide-mediated oxidation of methionine residues in granulocyte colony-stimulating factor and human parathyroid hormone fragment 13-34
Yin, Jin, Chu, Jhih-Wei, Ricci, Margaret Speed, Brems, David N, Wang, Daniel I C, Trout, Bernhardt L
Published in Pharmaceutical research (01.12.2004)
Published in Pharmaceutical research (01.12.2004)
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Journal Article
HOMOGENEOUS ANTIBODY POPULATION
ALAIN BALLAND, AMY GUO, JETTE WYPYCH, SHEN WENYAN, SUN JEONGHOON, MARTIN ALLEN, RICCI MARGARET SPEED, PAVEL BONDARENKO, THOMAS M DILLON, CHRIS VEZINA
Year of Publication 04.01.2022
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Year of Publication 04.01.2022
Patent
HOMOGENEOUS ANTIBODY POPULATIONS
ALAIN BALLAND, AMY GUO, JETTE WYPYCH, SHEN WENYAN, SUN JEONGHOON, MARTIN ALLEN, RICCI MARGARET SPEED, PAVEL BONDARENKO, THOMAS M DILLON, CHRIS VEZINA
Year of Publication 23.04.2020
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Year of Publication 23.04.2020
Patent
HOMOGENEOUS ANTIBODY POPULATION
ALAIN BALLAND, AMY GUO, JETTE WYPYCH, SHEN WENYAN, SUN JEONGHOON, MARTIN ALLEN, RICCI MARGARET SPEED, PAVEL BONDARENKO, THOMAS M DILLON, CHRIS VEZINA
Year of Publication 07.06.2018
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Year of Publication 07.06.2018
Patent
HOMOGENEOUS ANTIBODY POPULATION
ALAIN BALLAND, AMY GUO, JETTE WYPYCH, SHEN WENYAN, SUN JEONGHOON, MARTIN ALLEN, RICCI MARGARET SPEED, PAVEL BONDARENKO, THOMAS M DILLON, CHRIS VEZINA
Year of Publication 12.08.2016
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Year of Publication 12.08.2016
Patent
Rational design of lyophilized high concentration protein formulations-mitigating the challenge of slow reconstitution with multidisciplinary strategies
Cao, Wenjin, Krishnan, Sampathkumar, Ricci, Margaret Speed, Shih, Liang-Yu, Liu, Dingjiang, Gu, Jian Hua, Jameel, Feroz
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2013)
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2013)
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Journal Article
In-use physicochemical and microbiological stability of biological parenteral products
RICCI, MARGARET SPEED, FRAZIER, MICHELLE, MOORE, JAMIE, CROMWELL, MARY, GALUSH, WILLIAM J, PATEL, ANKIT R, ADLER, MICHAEL, ALTENBURGER, ULRIKE, GRAUSCHOPF, ULLA, GOLDBACH, PIERRE, FAST, JONAS L, KRÄMER, IRENE, MAHLER, HANNS-CHRISTIAN
Published in American journal of health-system pharmacy (01.03.2015)
Published in American journal of health-system pharmacy (01.03.2015)
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Journal Article
A Case Study of Nondelamination Glass Dissolution Resulting in Visible Particles: Implications for Neutral pH Formulations
Ratnaswamy, Gayathri, Hair, Alison, Li, Gary, Thirumangalathu, Renuka, Nashed-Samuel, Yasser, Brych, Lejla, Dharmavaram, Vasumathi, Wen, Zai-Qing, Fujimori, Kiyoshi, Jing, Wendy, Sethuraman, Ananth, Swift, Rob, Ricci, Margaret Speed, Piedmonte, Deirdre Murphy
Published in Journal of pharmaceutical sciences (01.04.2014)
Published in Journal of pharmaceutical sciences (01.04.2014)
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Journal Article
Oxidation of Methionine Residues in Recombinant Human Interleukin-1 Receptor Antagonist: Implications of Conformational Stability on Protein Oxidation Kinetics
Thirumangalathu, Renuka, Krishnan, Sampathkumar, Bondarenko, Pavel, Speed-Ricci, Margaret, Randolph, Theodore W, Carpenter, John F, Brems, David N
Published in Biochemistry (Easton) (29.05.2007)
Published in Biochemistry (Easton) (29.05.2007)
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Journal Article
A comprehensive picture of non‐site specific oxidation of methionine residues by peroxides in protein pharmaceuticals
Chu, Jhih‐Wei, Yin, Jin, Brooks, Bernard R., Wang, Daniel I.C., Ricci, Margaret Speed, Brems, David N., Trout, Bernhardt L.
Published in Journal of pharmaceutical sciences (01.12.2004)
Published in Journal of pharmaceutical sciences (01.12.2004)
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Journal Article