Mechanism of Active Renal Tubular Efflux of Tenofovir
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Xu, Lianhong, Liu, Hongtao, Murray, Bernard P, Callebaut, Christian, Lee, Melody S, Hong, Allen, Strickley, Robert G, Tsai, Luong K, Stray, Kirsten M, Wang, Yujin, Rhodes, Gerry R, Desai, Manoj C
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Published in ACS medicinal chemistry letters (12.08.2010)
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Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)
Xu, Lianhong, Liu, Hongtao, Hong, Allen, Vivian, Randy, Murray, Bernard P., Callebaut, Christian, Choi, You-Chul, Lee, Melody S., Chau, Jennifer, Tsai, Luong K., Stray, Kirsten M., Strickley, Robert G., Wang, Jianhong, Tong, Leah, Swaminathan, Swami, Rhodes, Gerry R., Desai, Manoj C.
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge
GUANG YANG, PEVEAR, Daniel C, HUGGINS, John W, BAKER, Robert O, BULLER, R. L, TOUCHETTE, Erin, WALLER, Kem, SCHRIEWER, Jill, NEYTS, Johan, DECLERCQ, Erik, JONES, Kevin, HRUBY, Dennis, DAVIES, Marc H, JORDAN, Robert, COLLETT, Marc S, BAILEY, Tom, RIPPEN, Susan, BARONE, Linda, BURNS, Chris, RHODES, Gerry, TOHAN, Sanjeev
Published in Journal of Virology (01.10.2005)
Published in Journal of Virology (01.10.2005)
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Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers, part I: Core region
Liu, Hongtao, Xu, Lianhong, Hui, Hon, Vivian, Randy, Callebaut, Christian, Murray, Bernard P., Hong, Allen, Lee, Melody S., Tsai, Luong K., Chau, Jennifer K., Stray, Kirsten M., Cannizzaro, Carina, Choi, You-Chul, Rhodes, Gerry R., Desai, Manoj C.
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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Nucleotide Analogue Prodrug Tenofovir Disoproxil Enhances Lymphoid Cell Loading following Oral Administration in Monkeys
Durand-Gasselin, Lucie, Van Rompay, Koen K. A, Vela, Jennifer E, Henne, Ilana N, Lee, William A, Rhodes, Gerry R, Ray, Adrian S
Published in Molecular pharmaceutics (03.08.2009)
Published in Molecular pharmaceutics (03.08.2009)
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Prediction of bictegravir human pharmacokinetics from protein binding and in vitro-in vivo correlation
Wang, Jianhong, Lazerwith, Scott, Jin, Haolun, Morganelli, Philip, Pyun, Peter, Tang, Jennifer, Matles, Mike, Mwangi, Judy, Wang, Kelly, Eisenberg, Gene, Murray, Bernard P., Rhodes, Gerry, Zhang, Heather, Custodio, Joseph
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Published in Drug metabolism and pharmacokinetics (01.01.2018)
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Human pharmacokinetics prediction with an in vitro-in vivo correction factor approach and in vitro drug-drug interaction profile of bictegravir, a potent integrase-strand transfer inhibitor component in approved biktarvy® for the treatment of HIV-1 infection
Subramanian, Raju, Wang, Jianhong, Murray, Bernard, Custodio, Joseph, Hao, Jia, Lazerwith, Scott, MacLennan Staiger, Kelly, Mwangi, Judy, Sun, Hailing, Tang, Jennifer, Wang, Kelly, Rhodes, Gerry, Wijaya, Samantha, Zhang, Heather, Smith, Bill J.
Published in Xenobiotica (02.12.2022)
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Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late I Nai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties
Zablocki, Jeff A, Elzein, Elfatih, Li, Xiaofen, Koltun, Dmitry O, Parkhill, Eric Q, Kobayashi, Tetsuya, Martinez, Ruben, Corkey, Britton, Jiang, Haibo, Perry, Thao, Kalla, Rao, Notte, Gregory T, Saunders, Oliver, Graupe, Michael, Lu, Yafan, Venkataramani, Chandru, Guerrero, Juan, Perry, Jason, Osier, Mark, Strickley, Robert, Liu, Gongxin, Wang, Wei-Qun, Hu, Lufei, Li, Xiao-Jun, El-Bizri, Nesrine, Hirakawa, Ryoko, Kahlig, Kris, Xie, Cheng, Li, Cindy Hong, Dhalla, Arvinder K, Rajamani, Sridharan, Mollova, Nevena, Soohoo, Daniel, Lepist, Eve-Irene, Murray, Bernard, Rhodes, Gerry, Belardinelli, Luiz, Desai, Manoj C
Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
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Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late I(Na)i), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties
Zablocki, Jeff A., Elzein, Elfatih, Li, Xiaofen, Koltun, Dmitry O., Parkhill, Eric Q., Kobayashi, Tetsuya, Martinez, Ruben, Corkey, Britton, Jiang, Haibo, Perry, Thao, Kalla, Rao, Notte, Gregory T., Saunders, Oliver, Graupe, Michael, Lu, Yafan, Venkataramani, Chandru, Guerrero, Juan, Perry, Jason, Osier, Mark, Strickley, Robert, Liu, Gongxin, Wang, Wei-Qun, Hu, Lufei, Li, Xiao-Jun, El-Bizri, Nesrine, Hirakawa, Ryoko, Kahlig, Kris, Xie, Cheng, Li, Cindy Hong, Dhalla, Arvinder K., Rajamani, Sridharan, Mollova, Nevena, Soohoo, Daniel, Lepist, Eve-Irene, Murray, Bernard, Rhodes, Gerry, Belardinelle, Luiz, Desai, Manoj C.
Published in Journal of medicinal chemistry (13.10.2016)
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Preclinical characterization of the novel HCV NS3 protease inhibitor GS-9256
Yang, Huiling, Yang, Chris, Wang, Yujin, Rhodes, Gerry, Robinson, Margaret, Cheng, Guofeng, Qi, Xiaoping, Mo, Hongmei, Tian, Yang, Pakdaman, Rowchanak, Sheng, X Christopher, Kim, Choung U, Delaney, 4th, William E
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Published in Antiviral therapy (01.01.2017)
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N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of Novel Orthopoxvirus Egress Inhibitors
Bailey, Thomas R, Rippin, Susan R, Opsitnick, Elizabeth, Burns, Christopher J, Pevear, Daniel C, Collett, Marc S, Rhodes, Gerry, Tohan, Sanjeev, Huggins, John W, Baker, Robert O, Kern, Earl R, Keith, Kathy A, Dai, Dongcheng, Yang, Guang, Hruby, Dennis, Jordan, Robert
Published in Journal of medicinal chemistry (05.04.2007)
Published in Journal of medicinal chemistry (05.04.2007)
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The discovery and structure–activity relationships of pyrano[3,4- b]indole based inhibitors of hepatitis C virus NS5B polymerase
LaPorte, Matthew G., Draper, Tandy L., Miller, Lori E., Blackledge, Charles W., Leister, Lara K., Amparo, Eugene, Hussey, Alison R., Young, Dorothy C., Chunduru, Srinivas K., Benetatos, Christopher A., Rhodes, Gerry, Gopalsamy, Ariamala, Herbertz, Torsten, Burns, Christopher J., Condon, Stephen M.
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase
Mitchell, Michael L., Son, Jong Chan, Guo, Hongyan, Im, Yun-A, Cho, Eun Jung, Wang, Jianhong, Hayes, Jaclyn, Wang, Michael, Paul, Amber, Lansdon, Eric B., Chen, James M., Graupe, Doris, Rhodes, Gerry, He, Gong-Xin, Geleziunas, Romas, Xu, Lianhong, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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The effect of oral pleconaril on hepatic cytochrome P450 3A activity in healthy adults using intravenous midazolam as a probe
Ma, Joseph D, Nafziger, Anne N, Rhodes, Gerry, Liu, Siyu, Gartung, Anne M, Bertino, Jr, Joseph S
Published in Journal of clinical pharmacology (01.01.2006)
Published in Journal of clinical pharmacology (01.01.2006)
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The Discovery of Pyrano[3,4-b]indole-Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity
LaPorte, Matthew G., Jackson, Randy W., Draper, Tandy L., Gaboury, Janet A., Galie, Kristin, Herbertz, Torsten, Hussey, Alison R., Rippin, Susan R., Benetatos, Christopher A., Chunduru, Srinivas K., Christensen, Joel S., Coburn, Glen A., Rizzo, Christopher J., Rhodes, Gerry, O'Connell, John, Howe, Anita Y. M., Mansour, Tarek S., Collett, Marc S., Pevear, Daniel C., Young, Dorothy C., Gao, Tiejun, Tyrrell , D. Lorne J., Kneteman, Norman M., Burns, Christopher J., Condon, Stephen M.
Published in ChemMedChem (20.10.2008)
Published in ChemMedChem (20.10.2008)
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NOVEL HIV REVERSE TRANSCRIPTASE INHIBITORS
GUO HONGYAN, SON, JONG CHAN, MITCHELL MICHAEL L, LEE, ILL YOUNG, KIM CHOUNG U, RHODES GERRY, XU LIANHONG
Year of Publication 22.04.2010
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Year of Publication 22.04.2010
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