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Evidence for two distinct G-protein-coupled ADP receptors mediating platelet activation
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Discovery and Optimization of a Novel Series of Thrombin Receptor (PAR-1) Antagonists: Potent, Selective Peptide Mimetics Based on Indole and Indazole Templates
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Novel Drimane Sesquiterpene Esters from Aspergillus ustus var. pseudodeflectus with Endothelin Receptor Binding Activity
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Extracellular Mutations of Protease-Activated Receptor-1 Result in Differential Activation by Thrombin and Thrombin Receptor Agonist Peptide
Blackhart, B D, Ruslim-Litrus, L, Lu, C C, Alves, V L, Teng, W, Scarborough, R M, Reynolds, E E, Oksenberg, D
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Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y12)
SCARBOROUGH, Robert M, LAIBELMAN, Alan M, CLIZBE, Lane A, FRETTO, Larry J, CONLEY, Pamela B, REYNOLDS, Elwood E, SEDLOCK, David M, JANTZEN, Hans-Michael
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Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line
Rebois, Robert V, Reynolds, Elwood E, Toll, Lawrence, Howard, Bruce D
Published in Biochemistry (Easton) (18.03.1980)
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Endothelin is a positive inotropic agent in human and rat heart in vitro
SCHOMISCH MORAVEC, C, REYNOLDS, E. E, STEWART, R. W, BOND, M
Published in Biochemical and biophysical research communications (28.02.1989)
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Structure-activity relationships of a novel series of orally active nonpeptide ETA and ETA/B endothelin receptor-selective antagonists
Doherty, A M, Patt, W C, Repine, J, Edmunds, J J, Berryman, K A, Reisdorph, B R, Walker, D M, Haleen, S J, Keiser, J A, Flynn, M A
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Structure−Activity Relationships in a Series of Orally Active γ-Hydroxy Butenolide Endothelin Antagonists
Patt, William C, Edmunds, Jeremy J, Repine, Joseph T, Berryman, Kent A, Reisdorph, Billy R, Lee, Chet, Plummer, Mark S, Shahripour, Aurash, Haleen, Stephen J, Keiser, Joan A, Flynn, Mike A, Welch, Kathleen M, Reynolds, Elwood E, Rubin, Ron, Tobias, Brian, Hallak, Hussein, Doherty, Annette M
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Phorbol ester dissociates endothelin-stimulated phosphoinositide hydrolysis and arachidonic acid release in vascular smooth muscle cells
Reynolds, Elwood E., Mok, Lester L.S., Kurokawa, Shingo
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Structure-activity relationships of the potent combined endothelinA/endothelinB receptor antagonist Ac-DDip16-Leu-Asp-Ile-Ile-Trp21 (PD 142893): development of endothelinB receptor selective antagonists
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Adenosine 5'-triphosphate independent secretion from PC12 pheochromocytoma cells
Reynolds, Elwood E, Melega, William P, Howard, Bruce D
Published in Biochemistry (Easton) (14.09.1982)
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Discovery of a Novel Series of Orally Active Non-Peptide Endothelin-A (ETA) Receptor-Selective Antagonists
Doherty, Annette M, Patt, William C, Edmunds, Jeremy J, Berryman, Kent A, Reisdorph, Billy R, Plummer, Mark S, Shahripour, Aurash, Lee, Chet, Cheng, Xue-Min
Published in Journal of medicinal chemistry (01.04.1995)
Published in Journal of medicinal chemistry (01.04.1995)
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Design of a functional hexapeptide antagonist of endothelin
Cody, Wayne L, Doherty, Annette M, He, John X, DePue, Patricia L, Rapundalo, Stephen T, Hingorani, Gary A, Major, Terry C, Panek, Robert L, Dudley, David T
Published in Journal of medicinal chemistry (01.08.1992)
Published in Journal of medicinal chemistry (01.08.1992)
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STRUCTURE-ACTIVITY-RELATIONSHIPS OF THE POTENT COMBINED ENDOTHELIN-A ENDOTHELIN-B RECEPTOR ANTAGONIST AC-DDIP(16)-LEU-ASP-ILE-ILE-TRP(21) - DEVELOPMENT OF ENDOTHELIN-B RECEPTOR-SELECTIVE ANTAGONISTS
CODY, WL, HE, JX, DEPUE, PL, WAITE, LA, LEONARD, DM, SEFLER, AM, KALTENBRONN, JS, HALEEN, SJ, WALKER, DM, FLYNN, MA, WELCH, KM, REYNOLDS, EE, DOHERTY, AM
Published in Journal of medicinal chemistry (21.07.1995)
Published in Journal of medicinal chemistry (21.07.1995)
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Pharmacological Differences Between Rat and Human Endothelin B Receptors
Reynolds, E.E., Hwang, O., Flynn, M.A., Welch, K.M., Cody, W.L., Steinbaugh, B., He, J.X., Chung, F.Z., Doherty, A.M.
Published in Biochemical and biophysical research communications (17.04.1995)
Published in Biochemical and biophysical research communications (17.04.1995)
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Endothelin and PDGF enhance arachidonic acid release and DNA synthesis in vascular smooth muscle cells
Irons, C E, Flynn, M A, Mok, L M, Reynolds, E E
Published in The American journal of physiology (01.06.1996)
Published in The American journal of physiology (01.06.1996)
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