Highly specific off-target binding identified and eliminated during the humanization of an antibody against FGF receptor 4
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Published in mAbs (01.07.2011)
Published in mAbs (01.07.2011)
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Onartuzumab (MetMAb): Using Nonclinical Pharmacokinetic and Concentration―Effect Data to Support Clinical Development
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Published in Clinical cancer research (15.09.2013)
Published in Clinical cancer research (15.09.2013)
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A therapeutic anti-VEGF antibody with increased potency independent of pharmacokinetic half-life
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Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Complex formation of anti‐VEGF‐C with VEGF‐C released during blood coagulation resulted in an artifact in its serum pharmacokinetics
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Published in Pharmacology research & perspectives (01.04.2020)
Published in Pharmacology research & perspectives (01.04.2020)
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Death receptor 5 agonistic antibody PRO95780: preclinical pharmacokinetics and concentration–effect relationship support clinical dose and regimen selection
Xiang, Hong, Reyes, Arthur E., Eppler, Steve, Kelley, Sean, Damico-Beyer, Lisa A.
Published in Cancer chemotherapy and pharmacology (01.08.2013)
Published in Cancer chemotherapy and pharmacology (01.08.2013)
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The pharmacokinetics of an albumin-binding Fab (AB.Fab) can be modulated as a function of affinity for albumin
Nguyen, Allen, Reyes, Arthur E., Zhang, Min, McDonald, Paul, Wong, Wai Lee T., Damico, Lisa A., Dennis, Mark S.
Published in Protein engineering, design and selection (01.07.2006)
Published in Protein engineering, design and selection (01.07.2006)
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TREATMENT METHOD
PETERSON AMY C, HEGDE PRITI, REYES ARTHUR E. II, EPPLER STEVE, JUMBE NELSON L, XIANG HONG, BENDER BRENDAN C, MERCHANT MARK
Year of Publication 22.06.2011
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Year of Publication 22.06.2011
Patent
Death receptor 5 agonistic antibody PR095780: preclinical pharmacokinetics and concentration-effect relationship support clinical dose and regimen selection
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Published in Cancer chemotherapy and pharmacology (2013)
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Published in Cancer chemotherapy and pharmacology (2013)
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EPPLER, STEVE, XIANG, HONG, HEGDE, PRITI, REYES, ARTHUR E. II, MERCHANT, MARK, JUMBE, NELSON L, PETERSON, AMY C, BENDER, BRENDAN C
Year of Publication 20.07.2011
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Year of Publication 20.07.2011
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TREATMENT METHOD
EPPLER, STEVE, XIANG, HONG, HEGDE, PRITI, REYES, ARTHUR E. II, MERCHANT, MARK, JUMBE, NELSON L, PETERSON, AMY C, BENDER, BRENDAN C
Year of Publication 10.09.2010
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Year of Publication 10.09.2010
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EPPLER, STEVE, XIANG, HONG, HEGDE, PRITI, REYES, ARTHUR E., II, MERCHANT, MARK, JUMBE, NELSON L, PETERSON, AMY C, BENDER, BRENDAN C
Year of Publication 22.04.2010
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Year of Publication 22.04.2010
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PRITI HEGDE, AMY C. PETERSON, ARTHUR E. REYES II, HONG XIANG, STEVE EPPLER, NELSON L. JUMBE, MARK MERCHANT, BRENDAN C. BENDER
Year of Publication 22.04.2010
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Year of Publication 22.04.2010
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EPPLER, STEVE, XIANG, HONG, HEGDE, PRITI, REYES, ARTHUR E. II, MERCHANT, MARK, JUMBE, NELSON L, PETERSON, AMY C, BENDER, BRENDAN C
Year of Publication 22.04.2010
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Year of Publication 22.04.2010
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método para tratar câncer, método para avaliação de um paciente submetido ao tratamento de câncer, método para avaliação de um paciente que tem ou com suspeita de ter câncer e uso de um anticorpo anti-c-met
AMY C. PETERSON, PRITI HEGDE, ARTHUR E. REYES II, HONG XIANG, STEVE EPPLER, NELSON L. JUMBE, MARK MERCHANT, BRENDAN C. BENDER
Year of Publication 16.02.2016
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Year of Publication 16.02.2016
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Metodo para tratar cancer en un sujeto mediante la administracion de un anticuerpo anti-cmet solo en conjunto con un antagonista del receptor del factor de crecimiento epidermico (egfr)
EPPLER STEVE, HEGDE PRITI, JUMBE NELSON L.MERCHANT MARK, PETERSON AMY C, REYES ARTHUR E II, XIANG HONG, BENDER BRENDAN C
Year of Publication 03.02.2012
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Year of Publication 03.02.2012
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PETERSON AMY C, HEGDE PRITI, REYES ARTHUR E. II, EPPLER STEVE, JUMBE NELSON L, XIANG HONG, BENDER BRENDAN C, MERCHANT MARK
Year of Publication 12.10.2011
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Year of Publication 12.10.2011
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EPPLER, STEVE, XIANG, HONG, HEGDE, PRITI, REYES, ARTHUR E. II, MERCHANT, MARK, JUMBE, NELSON L, PETERSON, AMY C, BENDER, BRENDAN C
Year of Publication 10.05.2011
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Year of Publication 10.05.2011
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EPPLER, STEVE, XIANG, HONG, HEGDE, PRITI, REYES, ARTHUR E. II, MERCHANT, MARK, JUMBE, NELSON L, PETERSON, AMY C, BENDER, BRENDAN C
Year of Publication 16.06.2010
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Year of Publication 16.06.2010
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REYES 11 ARTHUR E, PETERSON AMY C, HEGDE PRITI, EPPLER STEVE, JUMBE NELSON L, XIANG HONG, BENDER BRENDAN C, MERCHANT MARK
Year of Publication 27.06.2012
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Year of Publication 27.06.2012
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