DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells
Bruyer, Angelique, Maes, Ken, Herviou, Laurie, Kassambara, Alboukadel, Seckinger, Anja, Cartron, Guillaume, Rème, Thierry, Robert, Nicolas, Requirand, Guilhem, Boireau, Stéphanie, Müller-Tidow, Carsten, Veyrune, Jean-luc, Vincent, Laure, Bouhya, Salahedine, Goldschmidt, Hartmut, Vanderkerken, Karin, Hose, Dirk, Klein, Bernard, De Bruyne, Elke, Moreaux, Jerome
Published in British journal of cancer (01.04.2018)
Published in British journal of cancer (01.04.2018)
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The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance
Ovejero, Sara, Viziteu, Elena, Dutrieux, Laure, Devin, Julie, Lin, Yea-Lih, Alaterre, Elina, Jourdan, Michel, Basbous, Jihane, Requirand, Guilhem, Robert, Nicolas, de Boussac, Hugues, Seckinger, Anja, Hose, Dirk, Vincent, Laure, Herbaux, Charles, Constantinou, Angelos, Pasero, Philippe, Moreaux, Jérôme
Published in Frontiers in immunology (09.12.2022)
Published in Frontiers in immunology (09.12.2022)
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Journal Article
Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma
Bruyer, Angélique, Dutrieux, Laure, de Boussac, Hugues, Martin, Thibaut, Chemlal, Djamila, Robert, Nicolas, Requirand, Guilhem, Cartron, Guillaume, Vincent, Laure, Herbaux, Charles, Lutzmann, Malik, Bret, Caroline, Pasero, Philippe, Moreaux, Jérôme, Ovejero, Sara
Published in Frontiers in oncology (06.12.2023)
Published in Frontiers in oncology (06.12.2023)
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Journal Article
Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors
Moreaux, Jérôme, Rème, Thierry, Leonard, Wim, Veyrune, Jean-Luc, Requirand, Guilhem, Goldschmidt, Hartmut, Hose, Dirk, Klein, Bernard
Published in Molecular cancer therapeutics (01.12.2012)
Published in Molecular cancer therapeutics (01.12.2012)
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Journal Article
Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration
Moreaux, Jerome, Hose, Dirk, Kassambara, Alboukadel, Reme, Thierry, Moine, Philippe, Requirand, Guilhem, Goldschmidt, Hartmut, Klein, Bernard
Published in Blood (27.01.2011)
Published in Blood (27.01.2011)
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Journal Article
PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs
Herviou, Laurie, Kassambara, Alboukadel, Boireau, Stéphanie, Robert, Nicolas, Requirand, Guilhem, Müller-Tidow, Carsten, Vincent, Laure, Seckinger, Anja, Goldschmidt, Hartmut, Cartron, Guillaume, Hose, Dirk, Cavalli, Giacomo, Moreaux, Jerome
Published in Clinical epigenetics (03.10.2018)
Published in Clinical epigenetics (03.10.2018)
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Journal Article
Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays
DE VOS, John, THYKJAER, Thomas, ROSSI, Jean-Francois, ØRNTOFT, Torben, KLEIN, Bernard, TARTE, Karin, ENSSLEN, Matthias, RAYNAUD, Pierre, REQUIRAND, Guilhem, PELLET, Florence, PANTESCO, Véronique, REME, Thierry, JOURDAN, Michel
Published in Oncogene (03.10.2002)
Published in Oncogene (03.10.2002)
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Journal Article
Integrative Multi-Omics Analysis of Tumor-Immune Microenvironment in Multiple Myeloma: Novel Insights and Therapeutic Implications
Alaterre, Elina, Robert, Nicolas, Requirand, Guilhem, Machura, Amélie, De Boussac, Hugues, Vincent, Laure, Herbaux, Charles, Bruyer, Angélique, Moreaux, Jerome
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Translation Inhibition through eIF4A1 Targeting in Multiple Myeloma Is a Promising Therapeutic Strategy
Dutrieux, Laure, Loughran, Elle, Choquet, Armelle, Herault, Hélène, Guillemin, Antoine, Robert, Nicolas, Requirand, Guilhem, Cartron, Guillaume, Vincent, Laure, Herbaux, Charles, Rivals, Eric, David, Alexandre, Moreaux, Jerome
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Characterization of a New Metabolic Score Correlated with CD38 Cell-Surface Expression and Response to Daratumumab Treatment in Multiple Myeloma
Steer, Alizée, Alaterre, Elina, Chamlal, Djamila, Varlet, Emmanuel, Machura, Amélie, Kassambara, Alboukadel, Requirand, Guilhem, Robert, Nicolas, Vincent, Laure, Herbaux, Charles, De Boussac, Hugues, Bruyer, Angélique, Moreaux, Jerome
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Lipid-Mediated Modulation of DNA Damage Signaling As a Prognostic and Therapeutic Strategy Against Multiple Myeloma
Garcia De Paco, Elvira, Soulet, Caroline, Requirand, Guilhem, Robert, Nicolas, Cartron, Guillaume, Vincent, Laure, Herbaux, Charles, Moriel-Carretero, Maria, Moreaux, Jerome
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Development of a Robust BH3 Profiling Toolkit for Precision Medicine in Hematologic Malignancies
Jacquier, Valentin, Guillemin, Antoine, Ovejero-Merino, Sara, Requirand, Guilhem, Karmous-Gadacha, Ouissem, Dutrieux, Laure, Romero, Andrea, Steer, Alizée, Machura, Amelie, De Boussac, Hugues, Moreaux, Jerome, Herbaux, Charles
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
EZH2 Targeting Induces CD38 Upregulation and Response to Anti-CD38 Antibodies in Multiple Myeloma
Chemlal, Djamila, Varlet, Emmanuel, Machura, Amelie, Requirand, Guilhem, Robert, Nicolas, Alaterre, Elina, Vincent, Laure, Herbaux, Charles, Cavalli, Giacomo, Bruyer, Angélique, De Boussac, Hugues, Moreaux, Jerome
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma
Chemlal, Djamila, Varlet, Emmanuel, Machura, Amelie, Ovejero, Sara, Requirand, Guilhem, Robert, Nicolas, Cartron, Guillaume, Alaterre, Elina, Bret, Caroline, Vincent, Laure, Herbaux, Charles, Cavalli, Giacomo, Bruyer, Angélique, De Boussac, Hugues, Moreaux, Jerome
Published in Leukemia (02.08.2023)
Published in Leukemia (02.08.2023)
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Journal Article
Genomic Characterization of in Vitro Acquired-Resistance to Proteasome Inhibitors
De Boussac, Hugues, Kassambara, Alboukadel, Machura, Amelie, Chemlal, Djamila, Gourzones, Claire, Requirand, Guilhem, Robert, Nicolas, Vincent, Laure, Herbaux, Charles, Bruyer, Angélique, Moreaux, Jerome
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Exploiting Transcription-Replication Conflicts As a Novel Therapeutic Intervention in Multiple Myeloma
Dutrieux, Laure, Lin, Yea-Lih, Lutzmann, Malik, Requirand, Guilhem, Robert, Nicolas, Vincent, Laure, Cartron, Guillaume, Herbaux, Charles, Rodriguez, Raphael, Cogne, Michel, Pasero, Philippe, Moreaux, Jerome
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin ( CALR ) in exon 3
Bonnet, Sarah, Carillo, Serge, Legrand, Baptiste, Burroni, Barbara, Lavabre-Bertrand, Thierry, Requirand, Guilhem, Robert, Nicolas, Fornero, Lea, Al Mansoori, Ahmed, Moreaux, Jérôme, Cartron, Guillaume, Gabellier, Ludovic, Herbaux, Charles
Published in European journal of haematology (02.11.2023)
Published in European journal of haematology (02.11.2023)
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Journal Article
EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma
Chemlal, Djamila, Varlet, Emmanuel, Machura, Amelie, Ovejero, Sara, Requirand, Guilhem, Robert, Nicolas, Cartron, Guillaume, Alaterre, Elina, Bret, Caroline, Vincent, Laure, Herbaux, Charles, Cavalli, Giacomo, Bruyer, Angélique, de Boussac, Hugues, Moreaux, Jerome
Published in Leukemia (02.08.2023)
Published in Leukemia (02.08.2023)
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Journal Article
Ironomycin Induces Mantle Cell Lymphoma Cell Death By Targeting Iron Metabolism Addiction
ovejero-Merino, Sara, Alibert, Laura, Devin, Julie, Cañeque, Tatiana, Karmous Gadacha, Ouissem, Abouladze, Matthieu, Requirand, Guilhem, Robert, Nicolas, De Boussac, Hugues, Cartron, Guillaume, Herbaux, Charles, Rodriguez, Raphael, Moreaux, Jerome, Bret, Caroline
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Targeting Iron Homeostasis As a Therapeutic Strategy in Multiple Myeloma
ovejero-Merino, Sara, Devin, Julie, Cañeque, Tatiana, Alibert, Laura, Requirand, Guilhem, Robert, Nicolas, Steer, Alizée, Machura, Amelie, Hirtz, Christophe, Bruyer, Angélique, Vincent, Laure, Cartron, Guillaume, Herbaux, Charles, Rodriguez, Raphael, Bret, Caroline, Moreaux, Jerome
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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