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Allahyar, Amin, Vermeulen, Carlo, Bouwman, Britta A M, Krijger, Peter H L, Verstegen, Marjon J A M, Geeven, Geert, van Kranenburg, Melissa, Pieterse, Mark, Straver, Roy, Haarhuis, Judith H I, Jalink, Kees, Teunissen, Hans, Renkens, Ivo J, Kloosterman, Wigard P, Rowland, Benjamin D, de Wit, Elzo, de Ridder, Jeroen, de Laat, Wouter
Published in Nature genetics (01.08.2018)
Published in Nature genetics (01.08.2018)
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Mapping and phasing of structural variation in patient genomes using nanopore sequencing
Cretu Stancu, Mircea, van Roosmalen, Markus J, Renkens, Ivo, Nieboer, Marleen M, Middelkamp, Sjors, de Ligt, Joep, Pregno, Giulia, Giachino, Daniela, Mandrile, Giorgia, Espejo Valle-Inclan, Jose, Korzelius, Jerome, de Bruijn, Ewart, Cuppen, Edwin, Talkowski, Michael E, Marschall, Tobias, de Ridder, Jeroen, Kloosterman, Wigard P
Published in Nature communications (06.11.2017)
Published in Nature communications (06.11.2017)
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Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing
Stangl, Christina, de Blank, Sam, Renkens, Ivo, Westera, Liset, Verbeek, Tamara, Valle-Inclan, Jose Espejo, González, Rocio Chamorro, Henssen, Anton G., van Roosmalen, Markus J., Stam, Ronald W., Voest, Emile E., Kloosterman, Wigard P., van Haaften, Gijs, Monroe, Glen R.
Published in Nature communications (05.06.2020)
Published in Nature communications (05.06.2020)
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Micronuclei-based model system reveals functional consequences of chromothripsis in human cells
Kneissig, Maja, Keuper, Kristina, de Pagter, Mirjam S, van Roosmalen, Markus J, Martin, Jana, Otto, Hannah, Passerini, Verena, Campos Sparr, Aline, Renkens, Ivo, Kropveld, Fenna, Vasudevan, Anand, Sheltzer, Jason M, Kloosterman, Wigard P, Storchova, Zuzana
Published in eLife (28.11.2019)
Published in eLife (28.11.2019)
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Chromothripsis in Healthy Individuals Affects Multiple Protein-Coding Genes and Can Result in Severe Congenital Abnormalities in Offspring
de Pagter, Mirjam S., van Roosmalen, Markus J., Baas, Annette F., Renkens, Ivo, Duran, Karen J., van Binsbergen, Ellen, Tavakoli-Yaraki, Masoumeh, Hochstenbach, Ron, van der Veken, Lars T., Cuppen, Edwin, Kloosterman, Wigard P.
Published in American journal of human genetics (02.04.2015)
Published in American journal of human genetics (02.04.2015)
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Multi-contact 4C: long-molecule sequencing of complex proximity ligation products to uncover local cooperative and competitive chromatin topologies
Vermeulen, Carlo, Allahyar, Amin, Bouwman, Britta A M, Krijger, Peter H L, Verstegen, Marjon J A M, Geeven, Geert, Valdes-Quezada, Christian, Renkens, Ivo, Straver, Roy, Kloosterman, Wigard P, de Ridder, Jeroen, de Laat, Wouter
Published in Nature protocols (01.02.2020)
Published in Nature protocols (01.02.2020)
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Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
Kloosterman, Wigard P, Hoogstraat, Marlous, Paling, Oscar, Tavakoli-Yaraki, Masoumeh, Renkens, Ivo, Vermaat, Joost S, van Roosmalen, Markus J, van Lieshout, Stef, Nijman, Isaac J, Roessingh, Wijnand, van’t Slot, Ruben, van de Belt, José, Guryev, Victor, Koudijs, Marco, Voest, Emile, Cuppen, Edwin
Published in Genome Biology (19.10.2011)
Published in Genome Biology (19.10.2011)
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Constitutional Chromothripsis Rearrangements Involve Clustered Double-Stranded DNA Breaks and Nonhomologous Repair Mechanisms
Kloosterman, Wigard P., Tavakoli-Yaraki, Masoumeh, van Roosmalen, Markus J., van Binsbergen, Ellen, Renkens, Ivo, Duran, Karen, Ballarati, Lucia, Vergult, Sarah, Giardino, Daniela, Hansson, Kerstin, Ruivenkamp, Claudia A.L., Jager, Myrthe, van Haeringen, Arie, Ippel, Elly F., Haaf, Thomas, Passarge, Eberhard, Hochstenbach, Ron, Menten, Björn, Larizza, Lidia, Guryev, Victor, Poot, Martin, Cuppen, Edwin
Published in Cell reports (Cambridge) (28.06.2012)
Published in Cell reports (Cambridge) (28.06.2012)
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Genomic and transcriptomic plasticity in treatment-naive ovarian cancer
Hoogstraat, Marlous, de Pagter, Mirjam S, Cirkel, Geert A, van Roosmalen, Markus J, Harkins, Timothy T, Duran, Karen, Kreeftmeijer, Jennifer, Renkens, Ivo, Witteveen, Petronella O, Lee, Clarence C, Nijman, Isaac J, Guy, Tanisha, van 't Slot, Ruben, Jonges, Trudy N, Lolkema, Martijn P, Koudijs, Marco J, Zweemer, Ronald P, Voest, Emile E, Cuppen, Edwin, Kloosterman, Wigard P
Published in Genome research (01.02.2014)
Published in Genome research (01.02.2014)
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Multiplexed array-based and in-solution genomic enrichment for flexible and cost-effective targeted next-generation sequencing
Harakalova, Magdalena, Mokry, Michal, Hrdlickova, Barbara, Renkens, Ivo, Duran, Karen, van Roekel, Henk, Lansu, Nico, van Roosmalen, Mark, de Bruijn, Ewart, Nijman, Isaac J, Kloosterman, Wigard P, Cuppen, Edwin
Published in Nature protocols (01.12.2011)
Published in Nature protocols (01.12.2011)
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Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients
Valle-Inclan, Jose Espejo, Stangl, Christina, de Jong, Anouk C, van Dessel, Lisanne F, van Roosmalen, Markus J, Helmijr, Jean C A, Renkens, Ivo, Janssen, Roel, de Blank, Sam, de Witte, Chris J, Martens, John W M, Jansen, Maurice P H M, Lolkema, Martijn P, Kloosterman, Wigard P
Published in Genome medicine (18.05.2021)
Published in Genome medicine (18.05.2021)
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Accurate detection of circulating tumor DNA using nanopore consensus sequencing
Marcozzi, Alessio, Jager, Myrthe, Elferink, Martin, Straver, Roy, van Ginkel, Joost H, Peltenburg, Boris, Chen, Li-Ting, Renkens, Ivo, van Kuik, Joyce, Terhaard, Chris, de Bree, Remco, Devriese, Lot A, Willems, Stefan M, Kloosterman, Wigard P, de Ridder, Jeroen
Published in Npj genomic medicine (09.12.2021)
Published in Npj genomic medicine (09.12.2021)
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A multi-platform reference for somatic structural variation detection
Espejo Valle-Inclan, Jose, Besselink, Nicolle J.M., de Bruijn, Ewart, Cameron, Daniel L., Ebler, Jana, Kutzera, Joachim, van Lieshout, Stef, Marschall, Tobias, Nelen, Marcel, Priestley, Peter, Renkens, Ivo, Roemer, Margaretha G.M., van Roosmalen, Markus J., Wenger, Aaron M., Ylstra, Bauke, Fijneman, Remond J.A., Kloosterman, Wigard P., Cuppen, Edwin
Published in Cell genomics (08.06.2022)
Published in Cell genomics (08.06.2022)
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Author Correction: Accurate detection of circulating tumor DNA using nanopore consensus sequencing
Marcozzi, Alessio, Jager, Myrthe, Elferink, Martin, Straver, Roy, van Ginkel, Joost H, Peltenburg, Boris, Chen, Li-Ting, Renkens, Ivo, van Kuik, Joyce, Terhaard, Chris, de Bree, Remco, Devriese, Lot A, Willems, Stefan M, Kloosterman, Wigard P, de Ridder, Jeroen
Published in Npj genomic medicine (07.06.2023)
Published in Npj genomic medicine (07.06.2023)
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Genomic and Functional Overlap between Somatic and Germline Chromosomal Rearrangements
van Heesch, Sebastiaan, Simonis, Marieke, van Roosmalen, Markus J., Pillalamarri, Vamsee, Brand, Harrison, Kuijk, Ewart W., de Luca, Kim L., Lansu, Nico, Braat, A. Koen, Menelaou, Androniki, Hao, Wensi, Korving, Jeroen, Snijder, Simone, van der Veken, Lars T., Hochstenbach, Ron, Knegt, Alida C., Duran, Karen, Renkens, Ivo, Alekozai, Najla, Jager, Myrthe, Vergult, Sarah, Menten, Björn, de Bruijn, Ewart, Boymans, Sander, Ippel, Elly, van Binsbergen, Ellen, Talkowski, Michael E., Lichtenbelt, Klaske, Cuppen, Edwin, Kloosterman, Wigard P.
Published in Cell reports (Cambridge) (24.12.2014)
Published in Cell reports (Cambridge) (24.12.2014)
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Genomic DNA Pooling Strategy for Next-Generation Sequencing-Based Rare Variant Discovery in Abdominal Aortic Aneurysm Regions of Interest—Challenges and Limitations
Harakalova, Magdalena, Nijman, Isaäc J., Medic, Jelena, Mokry, Michal, Renkens, Ivo, Blankensteijn, Jan D., Kloosterman, Wigard, Baas, Annette F., Cuppen, Edwin
Published in Journal of cardiovascular translational research (01.06.2011)
Published in Journal of cardiovascular translational research (01.06.2011)
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Genome-wide patterns and properties of de novo mutations in humans
Francioli, Laurent C, Polak, Paz P, Koren, Amnon, Menelaou, Androniki, Chun, Sung, Renkens, Ivo, van Duijn, Cornelia M, Swertz, Morris, Wijmenga, Cisca, van Ommen, Gertjan, Slagboom, P Eline, Boomsma, Dorret I, Ye, Kai, Guryev, Victor, Arndt, Peter F, Kloosterman, Wigard P, de Bakker, Paul I W, Sunyaev, Shamil R
Published in Nature genetics (01.07.2015)
Published in Nature genetics (01.07.2015)
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CRISPR‐Cas9 enrichment, a new strategy in microbial metagenomics to investigate complex genomic regions: The case of an environmental integron
Sandoval‐Quintana, Eva, Stangl, Christina, Huang, Lionel, Renkens, Ivo, Duran, Robert, Haaften, Gijs, Monroe, Glen, Lauga, Béatrice, Cagnon, Christine
Published in Molecular ecology resources (01.08.2023)
Published in Molecular ecology resources (01.08.2023)
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Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML
Mulet-Lazaro, Roger, van Herk, Stanley, Erpelinck, Claudia, Bindels, Eric, Sanders, Mathijs A., Vermeulen, Carlo, Renkens, Ivo, Valk, Peter, Melnick, Ari M., de Ridder, Jeroen, Rehli, Michael, Gebhard, Claudia, Delwel, Ruud, Wouters, Bas J.
Published in Blood (15.07.2021)
Published in Blood (15.07.2021)
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A high-quality human reference panel reveals the complexity and distribution of genomic structural variants
Hehir-Kwa, Jayne Y, Marschall, Tobias, Kloosterman, Wigard P, Francioli, Laurent C, Baaijens, Jasmijn A, Dijkstra, Louis J, Abdellaoui, Abdel, Koval, Vyacheslav, Thung, Djie Tjwan, Wardenaar, René, Renkens, Ivo, Coe, Bradley P, Deelen, Patrick, de Ligt, Joep, Lameijer, Eric-Wubbo, van Dijk, Freerk, Hormozdiari, Fereydoun, Uitterlinden, André G, van Duijn, Cornelia M, Eichler, Evan E, de Bakker, Paul I W, Swertz, Morris A, Wijmenga, Cisca, van Ommen, Gert-Jan B, Slagboom, P Eline, Boomsma, Dorret I, Schönhuth, Alexander, Ye, Kai, Guryev, Victor
Published in Nature communications (06.10.2016)
Published in Nature communications (06.10.2016)
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