Search Results - "REN, Chaowei" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase

Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase

by Zhao, Quanju, Ren, Chaowei, Liu, Linyi, Chen, Jinju, Shao, Yubao, Sun, Ning, Sun, Renhong, Kong, Ying, Ding, Xinyu, Zhang, Xianfang, Xu, Youwei, Yang, Bei, Yin, Qianqian, Yang, Xiaobao, Jiang, Biao
Published in Journal of medicinal chemistry (24.10.2019)

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Journal Article

Construction of an IMiD-based azide library as a kit for PROTAC research

Construction of an IMiD-based azide library as a kit for PROTAC research

by Liu, Haixia, Sun, Renhong, Ren, Chaowei, Qiu, Xing, Yang, Xiaobao, Jiang, Biao
Published in Organic & biomolecular chemistry (06.01.2021)

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Journal Article

Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation

Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation

by Liu, Haixia, Ding, Xinyu, Liu, Linyi, Mi, Qianglong, Zhao, Quanju, Shao, YuBao, Ren, Chaowei, Chen, Jinju, Kong, Ying, Qiu, Xing, Elvassore, Nicola, Yang, Xiaobao, Yin, Qianqian, Jiang, Biao
Published in European journal of medicinal chemistry (05.11.2021)

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Journal Article

Reactive oxygen species-responsive Pre-PROTAC for tumor-specific protein degradation

Reactive oxygen species-responsive Pre-PROTAC for tumor-specific protein degradation

by Liu, Haixia, Ren, Chaowei, Sun, Renhong, Wang, Huihui, Zhan, Yuexiong, Yang, Xiaobao, Jiang, Biao, Chen, Hongli
Published in Chemical communications (Cambridge, England) (08.09.2022)

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Journal Article

Development of a Brigatinib degrader (SIAIS117) as a potential treatment for ALK positive cancer resistance

Development of a Brigatinib degrader (SIAIS117) as a potential treatment for ALK positive cancer resistance

by Sun, Ning, Ren, Chaowei, Kong, Ying, Zhong, Hui, Chen, Jinju, Li, Yan, Zhang, Jianshui, Zhou, Yuedong, Qiu, Xing, Lin, Haifan, Song, Xiaoling, Yang, Xiaobao, Jiang, Biao
Published in European journal of medicinal chemistry (01.05.2020)

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Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib

Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib

by Ren, Chaowei, Sun, Ning, Kong, Ying, Qu, Xiaojuan, Liu, Haixia, Zhong, Hui, Song, Xiaoling, Yang, Xiaobao, Jiang, Biao
Published in European journal of medicinal chemistry (05.05.2021)

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Design, synthesis and biological evaluation of novel quinazolinone derivatives as CRBN E3 ligase modulators

Design, synthesis and biological evaluation of novel quinazolinone derivatives as CRBN E3 ligase modulators

by Liu, Linyi, Sun, Renhong, Liu, Haixia, Ren, Chaowei, Zhou, Yuedong, Qiu, Xing, Kong, Ying, Jiang, Biao, Yang, Xiaobao
Published in European journal of medicinal chemistry (05.02.2023)

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Journal Article

Discovery of a Brigatinib Degrader SIAIS164018 with Destroying Metastasis-Related Oncoproteins and a Reshuffling Kinome Profile

by Ren, Chaowei, Sun, Ning, Liu, Haixia, Kong, Ying, Sun, Renhong, Qiu, Xing, Chen, Jinju, Li, Yan, Zhang, Jianshui, Zhou, Yuedong, Zhong, Hui, Yin, Qianqian, Song, Xiaoling, Yang, Xiaobao, Jiang, Biao
Published in Journal of medicinal chemistry (08.07.2021)

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Journal Article

Discovery and characterization of novel potent BCR-ABL degraders by conjugating allosteric inhibitor

Discovery and characterization of novel potent BCR-ABL degraders by conjugating allosteric inhibitor

by Liu, Haixia, Mi, Qianglong, Ding, Xinyu, Lin, Chencen, Liu, Linyi, Ren, Chaowei, Shen, ShuTing, Shao, YuBao, Chen, Jinju, Zhou, Yongqi, Ji, Liting, Zhang, Heqiao, Bai, Fang, Yang, Xiaobao, Yin, Qianqian, Jiang, Biao
Published in European journal of medicinal chemistry (15.12.2022)

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Journal Article

Corrigendum to “Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation” [Eur. J. Med. Chem. 223 (2021) 11–05 113645]

Corrigendum to “Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation” [Eur. J. Med. Chem. 223 (2021) 11–05 113645]

by Liu, Haixia, Ding, Xinyu, Liu, Linyi, Mi, Qianglong, Zhao, Quanju, Shao, YuBao, Ren, Chaowei, Chen, Jinju, Kong, Ying, Qiu, Xing, Elvassore, Nicola, Yang, Xiaobao, Yin, Qianqian, Jiang, Biao
Published in European journal of medicinal chemistry (05.04.2023)

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Journal Article

SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF

SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF

by LIU LINYI, YANG XIAOBAO, JIANG BIAO, SUN NING, SUN RENHONG, REN CHAOWEI, QIU XING
Year of Publication 21.02.2024

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Patent

글루타르이미드 골격을 기초로 하는 화합물 및 그 응용

글루타르이미드 골격을 기초로 하는 화합물 및 그 응용

by YANG XIAOBAO, JIANG BIAO, SUN NING, SUN RENHONG, REN CHAOWEI, QIU XING
Year of Publication 28.10.2022

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Patent

ALK 단백질 분해제 및 암 치료에서의 이의 용도

ALK 단백질 분해제 및 암 치료에서의 이의 용도

by YANG XIAOBAO, JIANG BIAO, LIN HAIFAN, SUN NING, CHEN JINJU, SONG XIAOLING, KONG YING, REN CHAOWEI, QIU XING
Year of Publication 21.09.2020

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Patent

표적 단백질 분해 화합물, 이의 항종양 응용, 이의 중간체 및 중간체의 응용

표적 단백질 분해 화합물, 이의 항종양 응용, 이의 중간체 및 중간체의 응용

by YANG XIAOBAO, JIANG BIAO, SUN NING, SUN RENHONG, CHEN JINJU, SONG XIAOLING, LI YAN, YIN QIANQIAN, KONG YING, ZHAO QUANJU, REN CHAOWEI, QIU XING
Year of Publication 18.01.2021

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Patent

IMMUNOREGULATORY COMPOUNDS AND ANTI-TUMOR APPLICATION THEREOF

IMMUNOREGULATORY COMPOUNDS AND ANTI-TUMOR APPLICATION THEREOF

by QIU, Xing, YANG, Xiaobao, JIANG, Biao, REN, Chaowei, LIU, Linyi
Year of Publication 29.08.2024

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Patent

IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF

IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF

by QIU, Xing, YANG, Xiaobao, JIANG, Biao, REN, Chaowei, LIU, Linyi
Year of Publication 10.01.2024

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Patent

IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF

IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF

by QIU, Xing, YANG, Xiaobao, JIANG, Biao, REN, Chaowei, LIU, Linyi
Year of Publication 28.09.2023

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Patent

IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF

IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF

by QIU, Xing, YANG, Xiaobao, JIANG, Biao, REN, Chaowei, LIU, Linyi
Year of Publication 21.06.2023

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Patent

Immunoregulatory compound and antitumor application thereof

Immunoregulatory compound and antitumor application thereof

by QIU, Xing, YANG, Xiaobao, JIANG, Biao, REN, Chaowei, LIU, Linyi
Year of Publication 13.04.2023

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Patent

HETEROCYCLE AND GLUTARIMIDE SKELETON-BASED COMPOUNDS AND APPLICATIONS THEREOF

HETEROCYCLE AND GLUTARIMIDE SKELETON-BASED COMPOUNDS AND APPLICATIONS THEREOF

by QIU, Xing, SUN, Renhong, YANG, Xiaobao, LIU, Haixia, JIANG, Biao, REN, Chaowei, LIU, Linyi, SUN, Ning
Year of Publication 14.12.2023

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Patent

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