Asymmetric Synthesis of Akt Kinase Inhibitor Ipatasertib
Han, Chong, Savage, Scott, Al-Sayah, Mohammad, Yajima, Herbert, Remarchuk, Travis, Reents, Reinhard, Wirz, Beat, Iding, Hans, Bachmann, Stephan, Fantasia, Serena M, Scalone, Michelangelo, Hell, André, Hidber, Pirmin, Gosselin, Francis
Published in Organic letters (15.09.2017)
Published in Organic letters (15.09.2017)
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Journal Article
Catalysis of Enantioselective [2+1]-Cycloaddition Reactions of Ethyl Diazoacetate and Terminal Acetylenes Using Mixed-Ligand Complexes of the Series Rh2(RCO2) n (L4 - n ). Stereochemical Heuristics for Ligand Exchange and Catalyst Synthesis
Lou, Yan, Remarchuk, Travis P, Corey, E. J
Published in Journal of the American Chemical Society (19.10.2005)
Published in Journal of the American Chemical Society (19.10.2005)
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Journal Article
Synthesis of Akt Inhibitor Ipatasertib. Part 2. Total Synthesis and First Kilogram Scale-up
Remarchuk, Travis, St-Jean, Frederic, Carrera, Diane, Savage, Scott, Yajima, Herbert, Wong, Brian, Babu, Srinivasan, Deese, Alan, Stults, Jeffrey, Dong, Michael W, Askin, David, Lane, Jonathan W, Spencer, Keith L
Published in Organic process research & development (19.12.2014)
Published in Organic process research & development (19.12.2014)
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Journal Article
Synthesis of Akt Inhibitor Ipatasertib. Part 1. Route Scouting and Early Process Development of a Challenging Cyclopentylpyrimidine Intermediate
Lane, Jonathan W, Spencer, Keith L, Shakya, Sagar R, Kallan, Nicholas C, Stengel, Peter J, Remarchuk, Travis
Published in Organic process research & development (19.12.2014)
Published in Organic process research & development (19.12.2014)
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Journal Article
Absorption, metabolism, and excretion of taselisib (GDC-0032), a PI3K inhibitor, in rats, dogs, and humans
Ma, Shuguang, Salphati, Laurent, Srikumar, Srikumar, Takahashi, Ryan, Ding, Xiao, Pang, Jodie, Wang, Bing, Remarchuk, Travis, Hsu, Jerry, Hop, Cornelis (Marcel), Ware, Joseph A., Khojasteh, S. Cyrus
Published in Drug metabolism and pharmacokinetics (01.01.2017)
Published in Drug metabolism and pharmacokinetics (01.01.2017)
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Journal Article
A synthesis of the HIV-protease inhibitor nelfinavir from d-tartaric acid
Albizati, Kim F, Babu, Srinivasan, Birchler, Angela, Busse, Juliette K, Fugett, Michelle, Grubbs, Alan, Haddach, Aubrey, Pagan, Miguel, Potts, Barbara, Remarchuk, Travis, Rieger, Dale, Rodriguez, Rick, Shanley, Jim, Szendroi, Robert, Tibbetts, Tony, Whitten, Kathleen, Borer, Bennett C
Published in Tetrahedron letters (10.09.2001)
Published in Tetrahedron letters (10.09.2001)
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Journal Article
An Efficient Catalytic Asymmetric Synthesis of a β2‑Amino Acid on Multikilogram Scale
Remarchuk, Travis, Babu, Srinivasan, Stults, Jeffrey, Zanotti-Gerosa, Antonio, Roseblade, Stephen, Yang, Shaohui, Huang, Ping, Sha, Chunbo, Wang, Youchu
Published in Organic process research & development (17.01.2014)
Published in Organic process research & development (17.01.2014)
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Journal Article
Stereoselective Synthesis of the IDO Inhibitor Navoximod
St-Jean, Frédéric, Angelaud, Rémy, Bachmann, Stephan, Carrera, Diane E, Remarchuk, Travis, Piechowicz, Katarzyna A, Niedermann, Katrin, Iding, Hans, Meier, Roland, Hou, Haiyun, Sirois, Lauren E, Xu, Jie, Olbrich, Martin, Rege, Pankaj, Guillemot-Plass, Maud, Gosselin, Francis
Published in Journal of organic chemistry (01.04.2022)
Published in Journal of organic chemistry (01.04.2022)
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Journal Article
피리미디닐아미노-피라졸 화합물의 변형 방출 제제, 및 치료 방법
RAVIVARAPU HARISH, SUDHAKAR ANANTHA, REMARCHUK TRAVIS, WONG BRADLEY K
Year of Publication 08.02.2022
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Year of Publication 08.02.2022
Patent
Manufacture of the PI3K β‑Sparing Inhibitor Taselisib. Part 1: Early-Stage Development Routes to the Bromobenzoxazepine Core
Remarchuk, Travis, Angelaud, Rémy, Askin, David, Kumar, Archana, Thompson, Andrew S, Cheng, Hua, Reichwein, John F, Chen, Yanping, St-Jean, Frédéric
Published in Organic process research & development (17.05.2019)
Published in Organic process research & development (17.05.2019)
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Journal Article
Manufacture of the PI3K β‑Sparing Inhibitor Taselisib. Part 2: Development of a Highly Efficient and Regioselective Late-Stage Process
St-Jean, Frédéric, Remarchuk, Travis, Angelaud, Rémy, Carrera, Diane E, Beaudry, Danial, Malhotra, Sushant, McClory, Andrew, Kumar, Archana, Ohlenbusch, Gerd, Schuster, Andreas M, Gosselin, Francis
Published in Organic process research & development (17.05.2019)
Published in Organic process research & development (17.05.2019)
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Journal Article
An Efficient Catalytic Asymmetric Synthesis of a β 2 -Amino Acid on Multikilogram Scale
Remarchuk, Travis, Babu, Srinivasan, Stults, Jeffrey, Zanotti-Gerosa, Antonio, Roseblade, Stephen, Yang, Shaohui, Huang, Ping, Sha, Chunbo, Wang, Youchu
Published in Organic process research & development (17.01.2014)
Published in Organic process research & development (17.01.2014)
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Journal Article